USP2 (NM_171997) Human 3' UTR Clone

Specifications

Product Data
Product Name	USP2 (NM_171997) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	UBP41; USP9
ACCN	NM_171997
Insert Size	1650 bp
Sequence Data	Insert Sequence (showhide) >SC215739 3’UTR clone of NM_171997 The sequence shown below is from the reference sequence of NM_171997. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAACTGGCCAGCCCGCCCTCCCGAATGTAGCGCCAGGAGCCACGTCCCTTCTCCCTTCCCCGTGGTGGC CCCGCTCCCTAAATTTTTTAAAAAGACAAAAACAAAACAACAACAACAACACACAAACCTGACAAGAGA AAAACAAACCTGAAGCTGCCGAGCAGGAGTGGATGCAGCCTGATCAGGGTCTGGAGCAAGGAGCCGGGC TTTCCTGAGCTGTGGCCCGGCAGGGAAGATCGCCTGGACGTGGAGCCAGCATCGCCCCGTGCCCTCGGC GTTTGCATTTGTAAACTTGTGGTCTTCCTATGTGTCAGAAACAACTGTGTCTTGGGGGGGAAGACCCTC GCTGCGCCGCTTCCCGCCGCAGCGCCCGCGCCTCCGAGGGGACAGCGCCCTCTGGAGCTCGCTGGGAGC ATCACCGCCTGGACGCCCGCGCCGCGGAGGAGCCGGCGCCCATCTCCACCCGCACGGCTCGCCGGTCCA GAGCCATGAGCCAAGAGCCCTCTTCACGCTGCTAACTCCAGGGGACAGACGAAGGGACATCTTTGGAAA ACGCTGGTTTTGGTTTTTAAAAAGCCCAACTTTTTTTTTTTAATTTCCATAACTAAAGTGTTCAGACTG GAGTGCTCTCCTTCAGGCCTCTTCATAGCTGGGACGTTGCACTGGTCCTTTTATTGCTTTTCCAAGTAC AACTTTCTAATGCTAGCCCTCCGTGGTGCTAGGTGGGCGTTGGCCAGGCCCCAAGCACAGCCACAGTAG ACCTGGGATCTAAAACAAGTTTCTGTTTTGGGGGTTTGGGTTTTTTTTTTTTTTTTTTAATGTTTTGAA TGGAATTTAGTTGCCTCCAAGAATTGTGCCTTATAGCATTTGGGGACCAGGGGGTAACTGCCCCTCCTG AAATATCCCTCAGCCTCTTCCCTTTTCCCCAGTGCTCTGTTCAAACCCGCCTGGGAAAGGGATCCTGCC CTTAGCCCTGGCTCGTTGTGCATTGCAGTGAGGCAAAGAAGAAAGCAGGTAGATTCCTTCCGACAGGGC ATCAAGTTCTTCCCGCCCACGTCCTCTAGCCCACCCCTGGTCTGCTCCCCAGCTGTTTGAAGGATAGCA CAAGCCCCTCGTCCCTAGAGCTTCTCTCCCTTTTATTTATTCTCTTAACATCCCTTTCCCCCTGGCCTT CCTGCCCCCGCCCCCTTCTCAGAGCCTCCTAGACAATAGGCCCTTTGGACCGAGTTTCTCAGGGATGCC CAGGCCACCCCTCAGCTCTTCTTAGCGCTGGTCTCCAGTCCTGCCCTGGGAGCTGGAGCCTGGGTATTT GGGGACATCTTGCCTCAGTTGTATGGTTCTTTCCTGTGGGCTCAATTTTGCCCTACATAGTTGGATAAA ACTCTGTGCTGTCCTGGAGAGTAAAGCTGTTCACCCACACAGCTGGGCCCGGCTTGTGCCCCGTGGAGC CTGGCACATTCCAGGCTCCTAGGAGGAGGCATCAGAGAAAGACACCCTGAGTTTTACTGGCCTGACACC CTTCTCCAGAGAAGACCTGTGAACCTGAGCCCAAGGGCAAGTGTACACTTGTTTACTGTGTAAGCAAGA GTAGAAGAATGTCTAATGTACAGTGGAACCTTGTACAGAATAAATAATAGCTTTGAGAAATCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_171997.3
Synonyms	UBP41; USP9
Summary	This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Locus ID	9099
MW	61.2

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