B7-2 (CD86) (NM_175862) Human 3' UTR Clone

Specifications

Product Data
Product Name	B7-2 (CD86) (NM_175862) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	B7-2; B7.2; B70; CD28LG2; LAB72
ACCN	NM_175862
Insert Size	1632 bp
Sequence Data	Insert Sequence (showhide) >SC215946 3’UTR clone of NM_175862 The sequence shown below is from the reference sequence of NM_175862. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCATGCGACAAAAGTGATACATGTTTTTAATTAAAGAGTAAAGCCCATACAAGTATTCATTTTTTCTAC CCTTTCCTTTGTAAGTTCCTGGGCAACCTTTTTGATTTCTTCCAGAAGGCAAAAAGACATTACCATGAG TAATAAGGGGGCTCCAGGACTCCCTCTAAGTGGAATAGCCTCCCTGTAACTCCAGCTCTGCTCCGTATG CCAAGAGGAGACTTTAATTCTCTTACTGCTTCTTTTCACTTCAGAGCACACTTATGGGCCAAGCCCAGC TTAATGGCTCATGACCTGGAAATAAAATTTAGGACCAATACCTCCTCCAGATCAGATTCTTCTCTTAAT TTCATAGATTGTGTTTTTTTTTTAAATAGACCTCTCAATTTCTGGAAAACTGCCTTTTATCTGCCCAGA ATTCTAAGCTGGTGCCCCACTGAATTTTGTGTGTACCTGTGACTAAACAACTACCTCCTCAGTCTGGGT GGGACTTATGTATTTATGACCTTATAGTGTTAATATCTTGAAACATAGAGATCTATGTACTGTAATAGT GTGATTACTATGCTCTAGAGAAAAGTCTACCCCTGCTAAGGAGTTCTCATCCCTCTGTCAGGGTCAGTA AGGAAAACGGTGGCCTAGGGTACAGGCAACAATGAGCAGACCAACCTAAATTTGGGGAAATTAGGAGAG GCAGAGATAGAACCTGGAGCCACTTCTATCTGGGCTGTTGCTAATATTGAGGAGGCTTGCCCCACCCAA CAAGCCATAGTGGAGAGAACTGAATAAACAGGAAAATGCCAGAGCTTGTGAACCCTGTTTCTCTTGAAG AACTGACTAGTGAGATGGCCTGGGGAAGCTGTGAAAGAACCAAAAGAGATCACAATACTCAAAAGAGAG AGAGAGAGAAAAAAGAGAGATCTTGATCCACAGAAATACATGAAATGTCTGGTCTGTCCACCCCATCAA CAAGTCTTGAAACAAGCAACAGATGGATAGTCTGTCCAAATGGACATAAGACAGACAGCAGTTTCCCTG GTGGTCAGGGAGGGGTTTTGGTGATACCCAAGTTATTGGGATGTCATCTTCCTGGAAGCAGAGCTGGGG AGGGAGAGCCATCACCTTGATAATGGGATGAATGGAAGGAGGCTTAGGACTTTCCACTCCTGGCTGAGA GAGGAAGAGCTGCAACGGAATTAGGAAGACCAAGACACAGATCACCCGGGGCTTACTTAGCCTACAGAT GTCCTACGGGAACGTGGGCTGGCCCAGCATAGGGCTAGCAAATTTGAGTTGGATGATTGTTTTTGCTCA AGGCAACCAGAGGAAACTTGCATACAGAGACAGATATACTGGGAGAAATGACTTTGAAAACCTGGCTCT AAGGTGGGATCACTAAGGGATGGGGCAGTCTCTGCCCAAACATAAAGAGAACTCTGGGGAGCCTGAGCC ACAAAAATGTTCCTTTATTTTATGTAAACCCTCAAGGGTTATAGACTGCCATGCTAGACAAGCTTGTCC ATGTAATATTCCCATGTTTTTACCCTGCCCCTGCCTTGATTAGACTCCTAGCACCTGGCTAGTTTCTAA CATGTTTTGTGCAGCACAGTTTTTAATAAATGCTTGTTACATTCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_175862.5
Synonyms	B7-2; B7.2; B70; CD28LG2; LAB72
Summary	This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
Locus ID	942
MW	62.7

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