HIPPI (IFT57) (NM_018010) Human 3' UTR Clone

Specifications

Product Data
Product Name	HIPPI (IFT57) (NM_018010) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ESRRBL1; HIPPI; MHS4R2; OFD18
ACCN	NM_018010
Insert Size	1695 bp
Sequence Data	Insert Sequence (showhide) >SC215991 3’UTR clone of NM_018010 The sequence shown below is from the reference sequence of NM_018010. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATTCCAGAACCAGCAACAGGCTTTTATTAAAACATACTGGTTTTCATGTTTCTGATTAGTTGGGTTTTT TATATCAAACTATATTTCATGTTGCATAGATTTCAAAACATAATTTTATGTTCAATGGGTATTTTTTTA CATATACATACTCACATATTATATCATGGTGATTATGATGGTTAAAGCCTTTACACTGAATGTAATGTT TAATAAAGAAATTACAAATTCTCACTTTCTAAGAAGCTTTCACTAATCATTACCTATGTTAAAGCTCCC ACCTGGTGGCTCATTTTTCATAGCATTCCTTGTGTAAGCCAAGGTATATGACCTGCGTTTTCTGCAGAT GCTGCTGCTGTCACAACATGAACTGCTGACACAGTCCTTTACCTTGCTCCACCTCTGCAGTGATCATAA GTGCTTTGTGCCCAGAGGCCACTGAAGATGGTAGGCAGGATTCTTTCCAAGAACCCAAACTGCCTTTGC CTCAGCTTTATGGTTACCTAAAATTGCCACTTTTTTTAGGTTAAAAAAAACTTCAGTATCCTCATTAAC ATTTGAAGTTGGTTTCTTATGAATATTTCGTGGCTAAAATGATTTTATAGGGAATCTATCTTCTAGGAT CTAAGCCACTAAATAAAAGGATAAATGAATGATGATAAGTCAGTCACTCATGTTTGACTCTGTTCTTAG AATGAAGAGAAGGTGCATATGCATGTCTCAATTTCTACCTTTTTCTGTGGTATCGGCTATACTAGGGAA CCATTTTGTAGAAGAAGGAACGATGACAGGTCGCATGAAGATCAGCCTCTAGTACTGATGATCTTTACT TATGCATCTTCCTGAGCAACTTTCTAGGCTAGGATTTCTAAATTGGTGAAAAAAGCAGCATTAGAGTGC CAGAATTAGCACTGGGGAAAACTGGCCAGGGGAACACAAAGCAGGAGACAGCCTGCGTTAATTTTTTTT TTTTAATAATTTTCAAAAGCAGTGGTAGAAAATTTGATAAGAATGCTTTATGTTTAGGACAACAAAAAT AATTTTAAAAAGTTATTTTTTACCCTAATACTTTTCTCCACTGAATATTATTATTTTTTTCTTAGCTTT TTCTTTCTAGATGTATTCCCCAACATGCTCACATACACAGATCTTTCCCTTTCCTTACTAGACCTCTCT TTAGTTTAAGATAAGTTTAGACAGGAGAAAGTGTATGTAAACTACCTGAAAGGATGACAATCAATACAA TGACAAATATGCCAGTTTATTTAATTTGTTTAAAAAAAAAAAGGCAGAAAACCCACCATGGGAAAATAA GCATTTTTTAAAATCTGAAGTTGCTCTTTTCCTGTGTGGTCTTTGGGAGGAGTCTAATACAAAAACTGA AAACCTTTGGTCCTGGGAATTTATTTTCATGGCTGTTGTCATGGCTGAGTAGTTTTTTGATGAATTCAA TCAATGCAGAGAACGCTTTTAGATAAATCAGAACTCTCCTTAAAATGCATTTCAATCAGAAGCAAAGTA CACCCATTATTTATGCAGACATGTAAAAAATCTAAAAATTCTTGCAATGAGTAGTATAAGCCACCTATT TTTACTTCCTTCTCTGAAATATTCCAGTTAACTCAGCTTGGGTTCTGTGCTCCTCCTCTCTTCCTATAG AACACTGTGCATACCTTGAATAAAGAGCTTATTATACTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_018010.4
Synonyms	ESRRBL1; HIPPI; MHS4R2; OFD18
Summary	Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.[UniProtKB/Swiss-Prot Function]
Locus ID	55081
MW	65.7

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.