STAT1 (NM_007315) Human 3' UTR Clone

Specifications

Product Data
Product Name	STAT1 (NM_007315) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91
ACCN	NM_007315
Insert Size	1584 bp
Sequence Data	Insert Sequence (showhide) >SC215993 3’UTR clone of NM_007315 The sequence shown below is from the reference sequence of NM_007315. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAATTCGACAGTATGATGAACACAGTATAGAGCATGAATTTTTTTCATCTTCTCTGGCGACAGTTTTCC TTCTCATCTGTGATTCCCTCCTGCTACTCTGTTCCTTCACATCCTGTGTTTCTAGGGAAATGAAAGAAA GGCCAGCAAATTCGCTGCAACCTGTTGATAGCAAGTGAATTTTTCTCTAACTCAGAAACATCAGTTACT CTGAAGGGCATCATGCATCTTACTGAAGGTAAAATTGAAAGGCATTCTCTGAAGAGTGGGTTTCACAAG TGAAAAACATCCAGATACACCCAAAGTATCAGGACGAGAATGAGGGTCCTTTGGGAAAGGAGAAGTTAA GCAACATCTAGCAAATGTTATGCATAAAGTCAGTGCCCAACTGTTATAGGTTGTTGGATAAATCAGTGG TTATTTAGGGAACTGCTTGACGTAGGAACGGTAAATTTCTGTGGGAGAATTCTTACATGTTTTCTTTGC TTTAAGTGTAACTGGCAGTTTTCCATTGGTTTACCTGTGAAATAGTTCAAAGCCAAGTTTATATACAAT TATATCAGTCCTCTTTCAAAGGTAGCCATCATGGATCTGGTAGGGGGAAAATGTGTATTTTATTACATC TTTCACATTGGCTATTTAAAGACAAAGACAAATTCTGTTTCTTGAGAAGAGAATATTAGCTTTACTGTT TGTTATGGCTTAATGACACTAGCTAATATCAATAGAAGGATGTACATTTCCAAATTCACAAGTTGTGTT TGATATCCAAAGCTGAATACATTCTGCTTTCATCTTGGTCACATACAATTATTTTTACAGTTCTCCCAA GGGAGTTAGGCTATTCACAACCACTCATTCAAAAGTTGAAATTAACCATAGATGTAGATAAACTCAGAA ATTTAATTCATGTTTCTTAAATGGGCTACTTTGTCCTTTTTGTTATTAGGGTGGTATTTAGTCTATTAG CCACAAAATTGGGAAAGGAGTAGAAAAAGCAGTAACTGACAACTTGAATAATACACCAGAGATAATATG AGAATCAGATCATTTCAAAACTCATTTCCTATGTAACTGCATTGAGAACTGCATATGTTTCGCTGATAT ATGTGTTTTTCACATTTGCGAATGGTTCCATTCTCTCTCCTGTACTTTTTCCAGACACTTTTTTGAGTG GATGATGTTTCGTGAAGTATACTGTATTTTTACCTTTTTCCTTCCTTATCACTGACACAAAAAGTAGAT TAAGAGATGGGTTTGACAAGGTTCTTCCCTTTTACATACTGCTGTCTATGTGGCTGTATCTTGTTTTTC CACTACTGCTACCACAACTATATTATCATGCAAATGCTGTATTCTTCTTTGGTGGAGATAAAGATTTCT TGAGTTTTGTTTTAAAATTAAAGCTAAAGTATCTGTATTGCATTAAATATAATATGCACACAGTGCTTT CCGTGGCACTGCATACAATCTGAGGCCTCCTCTCTCAGTTTTTATATAGATGGCGAGAACCTAAGTTTC AGTTGATTTTACAATTGAAATGACTAAAAAACAAAGAAGACAACATTAAAACAATATTGTTTCTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Reference Data
RefSeq	NM_007315.4
Synonyms	CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91
Summary	The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. The protein encoded by this gene can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. The protein plays an important role in immune responses to viral, fungal and mycobacterial pathogens. Mutations in this gene are associated with Immunodeficiency 31B, 31A, and 31C. [provided by RefSeq, Jun 2020]
Locus ID	6772
MW	62

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