EHD3 (NM_014600) Human 3' UTR Clone

Specifications

Product Data
Product Name	EHD3 (NM_014600) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	PAST3
ACCN	NM_014600
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC216018 3’UTR clone of NM_014600 The sequence shown below is from the reference sequence of NM_014600. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCCCCGTCCAAGAGGAAAGTTGCCGAGTGATGGGGTGGGGGGACATTCAGACGGGCAGTGTTAGAGGAG GAGATGGGAGCGGTGACTACACACACACACACACACACACACACACACACAAACATGCACACACACATA TGCATATCTTGACATTGCTCTGTAGGTGAGAGAGGACCATGACGCCCATGTTTGCAGCTGATACTTGTT TGGGCACACCTCCAAGTTCTCGGGATTAGAAGGACAAGAGCACTCCCAGGCCCCAGAGTCTAAGCCTAA GTCTCTATCGCTCTTCCCCTCTCCTCGGCCACTCCCCAGATACCAGACCTGAGGCAATTCACTTGCCAG CACAGATGGCCAACCCACCTCCAGATTCCCCAGTGCTTCCACACCCGGGCTCTGAGCAAATGGAAAAGA CTTTTCATTTAGTAGACAATTCACTTCTTTTTCTGTGCTTCCCCTATCTGCTTTGGCTTCCTAATAAGA AATCCATTCAAGAGCTAGGAGATCTGAGGGCAGGCGGGCAGCTGCAGGGAGGAGAGGTGAGAAAGGAAG CGTCTTCTAGAGACATTGGCCCAGGAGCTCTGTTCTTTCCTAATCTAAGCCTCTGTCTTCTTCGGCAAA CCTTGCTTTGAACTCTGCCAGTATTTCATTTTAAAGAATCCCAGAGCGGGAGAGAGAAGAGAAAAAAAT TGATAAGAGTGAGGAAATTGTCCTGTAGTCTATTGAAAACCAGTCAAGGTGGTTTTAGTTCATAGATTT TGTTAGATGTTCTTTCCACCTGGCCTATGATGTTTAGATGTTCATACTTGACTCACATTTACCCAGCCC CTCCTGCGTACCAGGAGCTGTGTTAGGCACTTTATATACATTATTCTATGTGGCCCTCACTGATGCCCC AGGGAAGTATGCATTAGCCTTCCCATTTTGCAGTTGAGGAGGCTGAGTAGCCTCAGAAGGGTTTAGGCG ACCTTCTGAAACTCACAGAAGTCACGTGATGGAGAGAGGATTCAAAGCCAGGGCCTCAGACCCTCACAC ACTTGTCTGTGCTATGATGTATGCAGGATCCCAGCATTGATACCCAATGACAAACTATGGAGAACAAGC AAAGTATGCAGGCCCCCTGCAGCCTCCCAGGACAGGCTGGCAAGGGAGGAGGGCCGGCCAGCATTTGGT GGCCCATCAGTCTGGCCATCTGTCACGTCACAGAAGCAAACCGTGCCTTCTGGCTCTGCGCCCCATATT CCCAGCATCATAGACATCCAACAGCACCAGCAGGAGAGTGGGCTAGCCTGCTGGATGCTGTTCGTGCCT GTCCCTGCTCTGCCTCCCACCCAGTTGCCTGAATCATCCCAGCTCAGATGCAGCCACTGTCTCTTGTCA AGTGGGACCTCATACTATTCTCAGAAGGCTAACTTGAGAGGTTTGGGGCCTTGTTCCCCAGAGGGTCCC CAGGGACTCTGCAGTGTCCTTGGCAAATCCCCACTGTACTCAATGCCCTACATTCTCTTCTGTGGTCTC TCCCCTGGCTTGCTTCATGGCCACTGAACCAATCACTTTGTATGCTATGCTCCTACTGTGATGGAAAAC AAAATGAGTATAACTTATTTTATATCCATATTCAGACTATATAGAGAATATTCTATGCATCTATGACGT GCTTACTACTGCAGTGCATTTGTCATTAGTCTTCATGTTAATACAGTACATTTATTCTTTGGTACCTGC CTGGCCACAGAGCATCATTCAATGGAGGCTGAGGGAGAAGGGCTGGGTTCTTACTTGGAGTTCCTGGTG AAATCTTTGGCTGGAAAGGGCTCACTGGGGCCACCCAATGGCCAGCATCCACAACCAGCTTCCCAGTGG GCTGGAGTTTGTCTAGGCTCAGTGACCAACCCAGGCACAGCTGGTGGAGCCACCGCTCCCTGCTCCTCT GGAGTGAAGATGTTCCCTAAGCCCCTGGGCTTCCTTCTGCAAATACACATTTCTCTTTCACATGAAAT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_014600.3
Synonyms	PAST3
Summary	ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis (PubMed:25686250). In vitro causes tubulation of endocytic membranes (PubMed:24019528). Binding to phosphatidic acid induces its membrane tubulation activity (By similarity). Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport. Involved in the regulation of Golgi maintenance and morphology (PubMed:16251358, PubMed:17233914, PubMed:19139087, PubMed:23781025). Involved in the recycling of internalized D1 dopamine receptor (PubMed:21791287). Plays a role in cardiac protein trafficking probably implicating ANK2 (PubMed:20489164). Involved in the ventricular membrane targeting of SLC8A1 and CACNA1C and probably the atrial membrane localization of CACNA1GG and CACNA1H implicated in the regulation of atrial myocyte excitability and cardiac conduction (By similarity). In conjunction with EHD4 may be involved in endocytic trafficking of KDR/VEGFR2 implicated in control of glomerular function (By similarity). Involved in the rapid recycling of integrin beta-3 implicated in cell adhesion maintenance (PubMed:23781025). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing (By similarity). Plays a role in the formation of the ciliary vesicle, an early step in cilium biogenesis; possibly sharing redundant functions with EHD1 (PubMed:25686250).[UniProtKB/Swiss-Prot Function]
Locus ID	30845
MW	74.4

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