SET (NM_001122821) Human 3' UTR Clone

Specifications

Product Data
Product Name	SET (NM_001122821) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	2PP2A; I2PP2A; IGAAD; IPP2A2; MRD58; PHAPII; TAF-I; TAF-IBETA
ACCN	NM_001122821
Insert Size	1762 bp
Sequence Data	Insert Sequence (showhide) >SC216281 3’UTR clone of NM_001122821 The sequence shown below is from the reference sequence of NM_001122821. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GGAGAGGAGGATGAAGGAGAAGATGACTAAATAGAACACTGATGGATTCCAACCTTCCTTTTTTTAAAT TTTCTCCAGTCCCTGGGAGCAAGTTGCAGTCTTTTTTTTTTTTTTTTTTTTTTTTCCCTCTTGTGCTCA GTCGCCCTGTTCTTGAGGTCTCTTTTCTCTACTCCATGGTTCTCAATTTATTTGGGGGGAAATACCTTG AGCAGAATACAATGGGAAAAGAGTCTCTACCCCTTTCTGTTCGAAGTTCATTTTTATCCCTTCCTGTCT GAACAAAAACTGTATGGAATCAACACCACCGAGCTCTGTGGGAAAAAAGAAAAACCTGCTCCCTTCGCT CTGCTGGAAGCTGGAGGGTGCTAGGCCCCTGTGTAGTAGTGCATAGAATTCTAGCTTTTTTCCTCCTTT CTCTGTATATTGGGCTCAGAGAGTACACTGTGTCTCTATGTGAATATGGACAGTTAGCATTTACCAACA TGTATCTGTCTACTTTCTCTTGTTTAAAAAAAGAAAAAAAAACTTAAAAAAATGGGGTTATAGAAGGTC AGCAAAGGGTGGGTTTGAGATGTTTGGGTGGGTTAAGTGGGCATTTTGACAACATGGCTTCTCCTTTGG CATGTTTAATTGTGATATTTGACAGACATCCTTGCAGTTTAAGATGACACTTTTAAAATAAATTCTCTC CTAATGATGACTTGAGCCCTGCCACTCAATGGGAGAATCAGCAGAACCTGTAGGATCTTATTTGGAATT GACATTCTCTATTGTAATTTTGTTCCTGTTTATTTTTAAATTTTCTTTTTGTTTCACTGGAAAGGAAAG ATGATGCTCAGTTTTAAACGTTAAAAGTGTACAAGTTGCTTTGTTACAATAAAACTAAATGTGTACACA AAGGATTTGATGCTTTTCTCTCAGCATAGGTATGCTTACTATGACCTTCCAAGTTTGACTTGTATAACA TCACTGTCAAACTTTGTCACCCTAACTTCGTATTTTTTGATACGCACTTTGCAGGATGACCTCAGGGCT ATGTGGATTGAGTAATGGGATTTGAATCAATGTATTAATATCTCCATAGCTGGGAAACGTGGGTTCAAT TTGCCATTGGTTTCTGAAAGTATTCACATCATTTGGGATACCAGATAGCTCAATACTCTCTGAGTACAT TGTGCCCTTGATTTTTATCTCCAAGTGGCAGTTTTTAAAATTGGCCTTTTACCTGGATATAAATTAATT GTGCCTGCCACCACCATCCAACAGACCTGGTGCTCTAATGCCAAGTTATACACGGGACAGTTGCTGGCA TGTCTTCATTGGCTATATAAAATGTGGCCAAGAAGATAGGCTCTCAGTAAGAAGTCTGATGGTGAGCAG TAACTGTCCCTGCTTTCTGGTATAAAGCTCTCAAATGTGACCATGTGAATCTGGGTGGGATAATGGACT CAGCTCTGTCTGCTCAATGCCATTGTGCAGAGAAGCACCCTAATGCATAAGCTTTTTAATGCTGTAAAA TATAGTCGCTGAAATTAAATGCCACTTTTTCAGAGGTGAATTAATGGACAGTCTGGTGAACTTCAAAAG CTTTTTGATGTATAAAACTTGATAAATGGAACTATTCCATCAATAGGCAAAAGTGTAACAACCTATCTA GATGGATAGTATGTAATTTCTGCACAGGTCTCTGTTTAGTAAATACATCACTGTATACCGATCAGGAAT CTTGCTCCAATAAAGGAACATAAAGATTTTTTTTGGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001122821.2
Synonyms	2PP2A; I2PP2A; IGAAD; IPP2A2; MRD58; PHAPII; TAF-I; TAF-IBETA
Summary	The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Locus ID	6418
MW	67.6

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