SynGAP (SYNGAP1) (NM_006772) Human 3' UTR Clone

Specifications

Product Data
Product Name	SynGAP (SYNGAP1) (NM_006772) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	MRD5; RASA1; RASA5; SYNGAP
ACCN	NM_006772
Insert Size	1813 bp
Sequence Data	Insert Sequence (showhide) >SC216425 3’UTR clone of NM_006772 The sequence shown below is from the reference sequence of NM_006772. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GGCGAGTTCCGAAACACCGCAGACCACTAGCCCACCCAGCATCAGAGACCTTCTCTTCCTTTCCTGTGC ACCCCACCCTGTAACAGCACCAACCACCAGGATTGGACATCACCGAGGAACAGCGGGATTGCCTCCCCG AATGCCTCCCTGGGAGGCACACTGATTGCCCACCCCCACCACTGCACCATTTCCAGGAGGGAGAGTGGG GACCCTCAGCCGCCCCCTTTTCCTTCCCATTGGGGTGCTGCCCTCTCTTTGACCCCCAGGGACCCTTGC CCCAGGACACCGCCTACCCCGTACAGACCCCTTCACTCCGGGGTGCTATCCCCATCCTCTGCCTCATCG TTCCCCTGAGCACTGGGGGACAGACCCTCACCCCCACCCTGGGGGTGTGGCACCTCCAAACTTTCAACT TCAGGGTGATTTTTTTAGCAGTAACCAGAGCTGACAATCTAACTCCCCTCCACCGCCCCATTTTGGCCT CCCCTGCCCCCCTTGTTATGGGGAGGGGACCCCGGGTGAGGGGGCCCTATTACCCCTTGATTTCTCAGG AGCGTCTGGGGGGGCTCAGCACGCACAAACTCCTTCTCCTTCTACCACTCTTAAATTTACTCCCTCCCC ACCCAGAACCCAGATGGGGTGGAGGGGGCCACCGGGGCAGGGAGGGGGCGGCAAGGGGGGAATGGGAGT TGTCTCCCCTTCTCCCCACACCTGATCTGCTCTCGGCTGGTCCCAGAGCGGGGTGAGGGGGCTTATGCC CCCCCCTCCCCCAGTGTGTTGGGTGGGGTGGAATTGAGGTTAGGGTGAGGGGTCAGGGTTTAGGAGGGT GTGTATGTTGGGAGGACAGGCTAGTTGATCTGTCCTACTCTGACACACAGTCCCCTCTGCCCCTTCCTT CTCTCTTCTTGGTCTCTACTCCCAGGGGGAGGGGGGAACTTACTCTAGGAAAAGCCATGTCTCTCTCCC CCAGGGTGGGGGGACCTGTGTTGGAGGAGGGGTGTTGGGGGGCCCCCTTCCATGACTCTGTCCCCTGGG GGAGGTAGGACAGGGCTGGGCTTCCCTCTCATCCTCCCCCTCCCAATCTCCTTCCACCTCCCTCCCTCC CGCCAGCTCCACGATTTTTCGGTGTTTCTCTGTACATAGTTTTCTGGCGGGATAGGGGAGGTAGGATGG ATGGGGTTTGGGGTGGGTAGGCCATGGGAGGGGAGAAGCCCCTCCTTGGCACCCCCTCTTCCCTGACTG CTGTCCCCTACCCAGCCTTGCCCCCTTCATCCTTTTGCGTTTGGTATTGAGACTCTCCTAGACTCTACT CCTCTTTCTTTTGTATGGACAGTTCCCCTTCAGTCCCATCCCCCTACACATACACCCAGCCGGGGCCAA ATTTATACTTATATAAAAGTTGTAAATATGTGAAATTTTATCCCTGTGCCCTTTCCCCACCTCAGGCCC TACCCCTGGACCCTCCCCAACCTTCCTTCTCTCTTCTTTGGCTGTTGTAATTATCTGGGGTTTGTACTG TACATATCCGGGGTGTGTGTGTGTGGGCTGGGGGCAACCCTTCTGTACAGAGCTTCCTGGCCCCCTCCC CCCCCGCCCCTCTGCTTCCCTCCCCACCCACCACCTCAAGGGTAGGGAGTTGCTCTTCCTACCTGTTTT ATTTTGTTTTCTCGTTCTCCCTCCCCACCCCACTCCCAGCCTTATCTATCCCCCCTCACTGTCCCCTTT TCTCCACTCCCAGCCCCATTTCCTTTTTTTCTGGAGTGTGTGGTGAAACAGAAAAAAACATGTTTAATA AACGGAGATTGTTCTTTTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006772.3
Synonyms	MRD5; RASA1; RASA5; SYNGAP
Summary	This gene encodes a Ras GTPase activating protein that is a member of the N-methyl-D-aspartate receptor complex. The N-terminal domain of the protein contains a Ras-GAP domain, a pleckstrin homology domain, and a C2 domain that may be involved in binding of calcium and phospholipids. The C-terminal domain consists of a ten histidine repeat region, serine and tyrosine phosphorylation sites, and a T/SXV motif required for postsynaptic scaffold protein interaction. The encoded protein negatively regulates Ras, Rap and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor trafficking to the postsynaptic membrane to regulate synaptic plasticity and neuronal homeostasis. Allelic variants of this gene are associated with intellectual disability and autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
Locus ID	8831
MW	64.7

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