Thymine DNA glycosylase (TDG) (NM_003211) Human 3' UTR Clone

Specifications

Product Data
Product Name	Thymine DNA glycosylase (TDG) (NM_003211) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	hTDG
ACCN	NM_003211
Insert Size	1814 bp
Sequence Data	Insert Sequence (showhide) >SC216483 3’UTR clone of NM_003211 The sequence shown below is from the reference sequence of NM_003211. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CAAGAACAGGAAGAAGAAAGCCATGCTTAAGAATGGTGCTTCTCAGCTCTGCTTAAATGCTGCAGTTTT AATGCAGTTGTCAACAAGTAGAACCTCAGTTTGCTAACTGAAGTGTTTTATTAGTATTTTACTCTAGTG GTGTAATTGTAATGTAGAACAGTTGTGTGGTAGTGTGAACCGTATGAACCTAAGTAGTTTGGAAGAAAA AGTAGGGTTTTTGTATACTAGCTTTTGTATTTGAATTAATTATCATTCCAGCTTTTTATATACTATATT TCATTTATGAAGAAATTGATTTTCTTTTGGGAGTCACTTTTAATCTGTAATTTTAAAATACAAGTCTGA ATATTTATAGTTGATTCTTAACTGCATAAACCTAGATATACCATTATCCCTTTTATACCTAAGAAGGGC ATGCTAATAATTACCACTGTCAAAGAGGCAAAGGTGTTGATTTTTGTATATGAAGTTAAGCCTCAGTGG AGTCTCATTTGTTAGTTTTTAGTGGTAACTAAGGGTAAACTCAGGGTTCCCTGAGCTATATGCACACTC AGACCTCTTTGCTTTACCAGTGGTGTTTGTGAGTTGCTCAGTAGTAAAAACTGGCCCTTACCTGACAGA GCCCTGGCTTTGACCTGCTCAGCCCTGTGTGTTAATCCTCTAGTAGCCAATTAACTACTCTGGGGTGGC AGGTTCCAGAGAATGCAGTAGACCTTTTGCCACTCATCTGTGTTTTACTTGAGACATGTAAATATGATA GGGAAGGAACTGAATTTCTCCATTCATATTTATAACCATTCTAGTTTTATCTTCCTTGGCTTTAAGAGT GTGCCATGGAAAGTGATAAGAAATGAACTTCTAGGCTAAGCAAAAAGATGCTGGAGATATTTGATACTC TCATTTAAACTGGTGCTTTATGTACATGAGATGTACTAAAATAAGTAATATAGAATTTTTCTTGCTAGG TAAATCCAGTAAGCCAATAATTTTAAAGATTCTTTATCTGCATCATTGCTGTTTGTTACTATAAATTAA ATGAACCTCATGGAAAGGTTGAGGTGTATACCTTTGTGATTTTCTAATGAGTTTTCCATGGTGCTACAA ATAATCCAGACTACCAGGTCTGGTAGATATTAAAGCTGGGTACTAAGAAATGTTATTTGCATCCTCTCA GTTACTCCTGAATATTCTGATTTCATACGTACCCAGGGAGCATGCTGTTTTGTCAATCAATATAAAATA TTTATGAGGTCTCCCCCACCCCCAGGAGGTTATATGATTGCTCTTCTCTTTATAATAAGAGAAACAAAT TCTTATTGTGAATCTTAACATGCTTTTTAGCTGTGGCTATGATGGATTTTATTTTTTCCTAGGTCAAGC TGTGTAAAAGTCATTTATGTTATTTAAATGATGTACTGTACTGCTGTTTACATGGACGTTTTGTGCGGG TGCTTTGAAGTGCCTTGCATCAGGGATTAGGAGCAATTAAATTATTTTTTCACGGGACTGTGTAAAGCA TGTAACTAGGTATTGCTTTGGTATATAACTATTGTAGCTTTACAAGAGATTGTTTTATTTGAATGGGGA AAATACCCTTTAAATTATGACGGACATCCACTAGAGATGGGTTTGAGGATTTTCCAAGCGTGTAATAAT GATGTTTTTCCTAACATGACAGATGAGTAGTAAATGTTGATATATCCTATACATGACAGTGTGAGACTT TTTCATTAAATAATATTGAAAGATTTTAAAATTCATTTGAAAGTCTGATGGCTTTTACAATAAAAGATA TTAAGAATTGTTATCCTTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003211.6
Synonyms	hTDG
Summary	The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008]
Locus ID	6996
MW	71.1

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