Neurofilament (NEFL) (NM_006158) Human 3' UTR Clone

Specifications

Product Data
Product Name	Neurofilament (NEFL) (NM_006158) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CMT1F; CMT2E; CMTDIG; NF-L; NF68; NFL; PPP1R110
ACCN	NM_006158
Insert Size	1885 bp
Sequence Data	Insert Sequence (showhide) >SC216811 3’UTR clone of NM_006158 The sequence shown below is from the reference sequence of NM_006158. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAGGAACAAGCAGCTAAGAAGAAAGATTGAACCCCCATTTCCTTAATTATTTCAGGAATAATTCTCCCG AAATCAGGTCAACCCCATCACCAACCAACCAACCAGTTGAGTTCCAGATTCTATGTGAATTAAAAAGTC AATATATGTATAATTCTGAGATGACTTAGGTTGGACATTCAATGTTGTGCTATGAATTTCCTCTTTATG CAGAGTATCTGTTTGCTTGCAGAGTGGCTTTCTGGCTTGCTGCCAGCCTGTGCATGGACCACGCTTATG AGTTCAGGATCTACGGCAATGTGAATCATTCAGATGTTTACAATAAAAAACACCACATGAGTAAATGAA TTCACTAATGTTAATGTTAAACTTCATGGAAAAATAGTCCTTTGAACCTTCGGTGGTTAGCAATTAAAG ACCCTGAGTTATGTGCAATAAATAGTAAATAAAGTTATACCGAATGATGTATTTTTTGCTGTGGTTGTT ACTTAATTAAAATACCTTAAAGATGGCACCAATATAAAGTATATACCAGTGGACTATTGACCTCCAATT TTTTAAAAAGTTGAAATTTTAACAATTACCAATACTTTTTTTTCTTCCTTCAATTGGAAATTCTGAGGG ATACAGTTATGTCATGATTACTTGTGAAATCTCTCCCCACAAAAATTTTACTGATAATAAACATGAGTA AATGAGAAAGTCTATAAATAACAATAGACTTTGCCTCATAACACGTGTTGTGTTAGGTTTTGGGATGGC TTTCTAGGGAGCAATTCTGAAATTACTTGACAGATACACTCTTTATGGTAAACAGGTCATTTCAGAGTC TAGAGTGCTAACCATTACACTATGGAACCATGATAAATAGGTCATTTCAAACTGATATGTCACAATGCA ATATGGATAGAATATGAATCCCATACATTCATCCCTATAACTGCATTTTAAAATATAGTCTAAATATCA TGGGAGGAGGTTAAAACCTGAGAACATGGTACAATAAGAAGGAATAATTTTTTATCTATATATAATTTC AGGAGAAGGGATTAAAACTACCAAAGGTTATTTGCCACTCCACTGCAAACATGTTGCCTGCAATCCTGA GCTCATGATTTAGTGTGTTGTTAAGCGTAATTCTGTTGCCTCAAGTAAATACCACTTAATGCTACACAT TTTTAAACCTTTAAAAGCTACAGACACAAGTAATGAAATTATGAGTCACTTAAGGGGGGAGGTAATATG CTTGTATGTTACATTGACATTGCTCTGCATGTCTCTACTGGGAGATATTTGGATTTCAATGATAGCTTG ACTGGTTGGACATTGCATCAAATACACGCCCCATGTATCCTTTCTGTCGTAAAGTTAAGAACGCTCTTG CATTTGATGTGGAATAAATATAGATGATATTACTATCTGCTATTCTGCCTTTGTTCTGAAACAATTGCT TTGTCAGCTAATTTCATTCAATATTTGTTTTTTAGACGATCTCTATAAGTTATTAATTTAACCTGAAAC CAAAGTGGTCTCCATTTAAAGTTACTTAATCCCTTTGTACCACCTATTTCTAGTTAAATATATGTTGCT ATGCAAATAGGTAAAGTGCTTCCTTGCCATGATGGTAATGGATTGGAACTATGAAGGCTCTCAGTGTAT TGGCTTCTGTAAAGATGAGGCGTCTCCTCAGAAACAAAACTTTTCACATTTCTGCTTACTAGACCTGGG TTGATGTACATGGTAAGTCTCAAACAGATGCAAGCTATGTGCAAAAAGTAACTTTAGCCAAATGGAAAT AGCTGGATGCTTTGAGAATTACTTGGTTGAAGTAAGAAAACTGTACCATCCTCTATCCTGTGTGCCATA ATAAAATAGTAAAAAACCTAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006158.5
Synonyms	CMT1F; CMT2E; CMTDIG; NF-L; NF68; NFL; PPP1R110
Summary	Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
Locus ID	4747
MW	72.2

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