CD46 (NM_172358) Human 3' UTR Clone

Specifications

Product Data
Product Name	CD46 (NM_172358) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AHUS2; MCP; MIC10; TLX; TRA2.10
ACCN	NM_172358
Insert Size	1939 bp
Sequence Data	Insert Sequence (showhide) >SC217030 3’UTR clone of NM_172358 The sequence shown below is from the reference sequence of NM_172358. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCACTCCAGCAGAGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTA TTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGTGCAACTGTGGCTTAGCTAATATT GCAATGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAA CAGATTGCCTGCTTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGT ATTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATTAGAGAAATATAGTTCACAATGAAATT ATATTTTCTTTGTAAAGAAAGTGGCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGATT ATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTTAAAAATATGTGTA TACTACTTTGGCTCTTGTGCATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTTGGCTTCT TTAACCAAGAATATTATTGGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTTTGTAATGTG TTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGTGGCATTTGTTTTCACTTTTTAAAACATCCCTAAC TGATCGAATATATCAGTAATTTCAGAATCAGATGCATCCTTTCATAAGAAGTGAGAGGACTCTGACAGC CATAACAGGAGTGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAAAGAGAACTC CGTATGTTCTCTTAGGTTGAGTAACCCACTCTGAATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAA ATAAAGAGAGGGGTTAAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATAAC CTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAAAAGCCATCTATGTATATGTC TTACCTCATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTGTC TATTTGCTGTTGATTGTACCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGC AGATCTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCAAAGAAGCCAGCAGGCGAAAAGCA GGGACTGCCACTGCATTTCATATCACACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCACA AATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGAAGAATAAATA CTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAA GATGCTTTAGGAAGATAAAAGTTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTTGAAGTT TATACCCGTTTCACATGCTTTTCAAGAATGTCGCAATTACTAAGAAGCAGATAATGGTGTTTTTTAGAA ACCTAATTGAAGTATATTCAACCAAATACTTTAATGTATAAAATAAATATTATACAATATACTTGTATA GCAGTTTCTGCTTCACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGTATAAAT ATGTATTTTGTCAAATTTGTTACTTAAATATATAGAGACCAGTTTTCTCTGGAAGTTTGTTTAAATGAC AGAAGCGTATATGAATTCAAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAAATGAGAAGTCTCAC TGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTGTTAAAATAAAATTGTAC ATTTGGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_172358.3
Synonyms	AHUS2; MCP; MIC10; TLX; TRA2.10
Summary	The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
Locus ID	4179
MW	74.9

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