Gremlin 1 (GREM1) (NM_013372) Human 3' UTR Clone

Specifications

Product Data
Product Name	Gremlin 1 (GREM1) (NM_013372) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	C15DUPq; CKTSF1B1; CRAC1; CRCS4; DAND2; DRM; DUP15q; GREMLIN; HMPS; HMPS1; IHG-2; MPSH; PIG2
ACCN	NM_013372
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC220862 3’UTR clone of NM_013372 The sequence shown below is from the reference sequence of NM_013372. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TGTCGTTGCATATCCATCGATTTGGATTAAGCCAAATCCAGGTGCACCCAGCATGTCCTAGGAATGCAG CCCCAGGAAGTCCCAGACCTAAAACAACCAGATTCTTACTTGGCTTAAACCTAGAGGCCAGAAGAACCC CCAGCTGCCTCCTGGCAGGAGCCTGCTTGTGCGTAGTTCGTGTGCATGAGTGTGGATGGGTGCCTGTGG GTGTTTTTAGACACCAGAGAAAACACAGTCTCTGCTAGAGAGCACTCCCTATTTTGTAAACATATCTGC TTTAATGGGGATGTACCAGAAACCCACCTCACCCCGGCTCACATCTAAAGGGGCGGGGCCGTGGTCTGG TTCTGACTTTGTGTTTTTGTGCCCTCCTGGGGACCAGAATCTCCTTTCGGAATGAATGTTCATGGAAGA GGCTCCTCTGAGGGCAAGAGACCTGTTTTAGTGCTGCATTCGACATGGAAAAGTCCTTTTAACCTGTGC TTGCATCCTCCTTTCCTCCTCCTCCTCACAATCCATCTCTTCTTAAGTTGATAGTGACTATGTCAGTCT AATCTCTTGTTTGCCAAGGTTCCTAAATTAATTCACTTAACCATGATGCAAATGTTTTTCATTTTGTGA AGACCCTCCAGACTCTGGGAGAGGCTGGTGTGGGCAAGGACAAGCAGGATAGTGGAGTGAGAAAGGGAG GGTGGAGGGTGAGGCCAAATCAGGTCCAGCAAAAGTCAGTAGGGACATTGCAGAAGCTTGAAAGGCCAA TACCAGAACACAGGCTGATGCTTCTGAGAAAGTCTTTTCCTAGTATTTAACAGAACCCAAGTGAACAGA GGAGAAATGAGATTGCCAGAAAGTGATTAACTTTGGCCGTTGCAATCTGCTCAAACCTAACACCAAACT GAAAACATAAATACTGACCACTCCTATGTTCGGACCCAAGCAAGTTAGCTAAACCAAACCAACTCCTCT GCTTTGTCCCTCAGGTGGAAAAGAGAGGTAGTTTAGAACTCTCTGCATAGGGGTGGGAATTAATCAAAA ACCTCAGAGGCTGAAATTCCTAATACCTTTCCTTTATCGTGGTTATAGTCAGCTCATTTCCATTCCACT ATTTCCCATAATGCTTCTGAGAGCCACTAACTTGATTGATAAAGATCCTGCCTCTGCTGAGTGTACCTG ACAGTAGTCTAAGATGAGAGAGTTTAGGGACTACTCTGTTTTAGCAAGAGATATTTTGGGGGTCTTTTT GTTTTAACTATTGTCAGGAGATTGGGCTAAAGAGAAGACGACGAGAGTAAGGAAATAAAGGGAATTGCC TCTGGCTAGAGAGTAGTTAGGTGTTAATACCTGGTAGAGATGTAAGGGATATGACCTCCCTTTCTTTAT GTGCTCACTGAGGATCTGAGGGGACCCTGTTAGGAGAGCATAGCATCATGATGTATTAGCTGTTCATCT GCTACTGGTTGGATGGACATAACTATTGTAACTATTCAGTATTTACTGGTAGGCACTGTCCTCTGATTA AACTTGGCCTACTGGCAATGGCTACTTAGGATTGATCTAAGGGCCAAAGTGCAGGGTGGGTGAACTTTA TTGTACTTTGGATTTGGTTAACCTGTTTTCTTCAAGCCTGAGGTTTTATATACAAACTCCCTGAATACT CTTTTTGCCTTGTATCTTCTCAGCCTCCTAGCCAAGTCCTATGTAATATGGAAAACAAACACTGCAGAC TTGAGATTCAGTTGCCGATCAAGGCTCTGGCATTCAGAGAACCCTTGCAACTCGAGAAGCTGTTTTTAT TTCGTTTTTGTTTTGATCCAGTGCTCTCCCATCTAACAACTAAACAGGAGCCATTTCAAGGCGGGAGAT ATTTTAAACACCCAAAATGTTGGGTCTGATTTTCAAACTTTTAAACTCACTACTGATGATTCTCACGCT AGGCGAATTTGTCCAAACACATAGTGTGTGTGTTTTGTATACACTGTATGACCCCACCCCAAATCTTT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_013372.7
Synonyms	C15DUPq; CKTSF1B1; CRAC1; CRCS4; DAND2; DRM; DUP15q; GREMLIN; HMPS; HMPS1; IHG-2; MPSH; PIG2
Summary	This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Locus ID	26585
MW	75.7

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