United States
Germany
Japan
United Kingdom
China
Mcl1 (NM_008562) Mouse Untagged Clone
CAT＃: MC200829
Mcl1 (untagged) - Mouse myeloid cell leukemia sequence 1 (Mcl1), nuclear gene encoding mitochondrial protein, (10ug)
CNY 3,600.00
| Cited in 3 publications. |
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AW556805; Mcl-1 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC021638 sequence for NM_008562
CCACGCGTCCGGCCTGCCTCCGGTCTGGAGTCGCGGCCTTCCCCGCTCCTTCCCCTCAGCCTGCGGCGTC CGACCATGTTTGGCCTGCGGAGAAACGCGGTCATCGGCTTGAACCTGTACTGCGGCGGCGCCAGCCTCGG CGCGGGCGGCGGTTCTCCGGCAGGGGCGCGCCTGGTGGCCGAGGAGGCCAAGGCGCGGCGCGAGGGGGGA GGGGAGGCCGCCCTGCTGCCCGGCGCGCGGGTGGTCGCCCGGCCGCCGCCCGTGGGCGCCGAGGACCCCG ACGTCACCGCGTCGGCCGAAAGGCGGCTGCATAAGTCGCCCGGCCTCCTCGCCGTGCCGCCCGAGGAGAT GGCCGCGTCGGCCGCCGCCGCCATCGTGTCTCCGGAGGAGGAACTGGACGGCTGCGAGCCGGAGGCCATC GGCAAGCGCCCGGCCGTGCTGCCCCTCCTGGAGCGCGTGAGCGAGGCGGCCAAGAGCTCCGGGGCCGACG GCTCTCTGCCCTCCACGCCGCCGCCGCCCGAGGAGGAAGAGGACGACCTATACCGCCAGTCGCTGGAGAT CATCTCGCGCTACTTGCGGGAGCAGGCGACCGGCTCCAAGGACTCGAAGCCTCTGGGCGAGGCGGGCGCG GCGGGCCGGAGAGCGCTGGAGACCCTGCGGCGCGTGGGCGACGGCGTGCAGCGCAACCACGAGACGGCCT TCCAGGGCATGCTCCGGAAACTGGACATTAAAAACGAAGGCGATGTTAAATCTTTTTCTCGAGTAATGGT CCATGTTTTCAAAGATGGCGTAACAAACTGGGGCAGGATTGTGACTCTTATTTCTTTCGGTGCCTTTGTG GCCAAACACTTAAAGAGCGTAAACCAAGAAAGCTTCATCGAACCATTAGCAGAAACTATCACAGATGTTC TTGTAAGGACGAAACGGGACTGGCTTGTCAAACAAAGAGGCTGGGATGGGTTTGTGGAGTTCTTCCACGT ACAGGACCTAGAAGGCGGCATCAGAAATGTGCTGCTGGCTTTTGCGGGTGTTGCTGGAGTAGGGGCTGGT CTGGCATATCTAATAAGATAGCCTTGTGAGTGCAATAGGGGACTCTTAAAGCTCCAGCCACCAAACTACA TGCATCTGTGAAAACATGTGTATTTATGAAGGTGGACTTGAAGCTGCCCAGGATTTTAACAGTCCAGTTC TACTGTAGCAACATAGCAAAAAGAAAGTGGCTACAGGATTGTGGCTAACAAGAATAAATACATGGGAAAA GTGCTCCCCCTGGAAGAGTCACTGTCTGAATGAAGCAAAGTTCCCTCTCAGCAAACACTGAGAGGCCATG GAGAAGGACTTCTAGAATGAATGAAAGGGGTGGATGGAAAGGTTTGATTTCCTATCTAGAGATGGAAGAG GGGCCAGTCATCAGGCTAGTCACAAAGCTCAATAAATATCCATTACTCTGCTCAGAGTGTTGAGAGAGAA GCCCTAATTAACAACGTTGGTGACTTGTGTAAAATGGATTTGTAACCTACAAGTCACCAAACGATGACTA GAAGCTGCAGTGCTGTACAGGAATGTGAAGGGAGGCCTCTGAGCAGTCCAGGGTGTGCTTGACAAAGTCC CAAGTGCTCAGGACTTTTAGCCCTGTCTACTTTGGCTTGGTTTGGATGATTCTTAAGTTTATTAGCCTAG TGATGGCCAAAAAGTACTTGACTTAAGGTTCACTAATTAGTTACAAAACTGAACAGCCTCGATTTTTAAG AAAATTTATGAAATGTATTTGTCTGTAAAAATTGTATATATTTTTACAGAAAGTCTATTTCTTTGAACAT AAGAGGGAAGTCTTGGATTTAGTTTTTTTCCATACCCTTTTGAAATTTGCAGCTTCTCTAGTTAGAAATG TATTTCTTACAGCTTTTTAAGACTTTGTCATCCGTTCTAGTGTATATGCAGAGCCTGTTGTGTGTGTGGA CTGGTTATAGATTTATAACTATGCAGGGTTAATTATCCAATCTTTTTTTTTTGTATTTAAAGATCACAGG TAGATAGATGTAAGACATTTGATCCCCTGTTGACTTACAAAATTGTAAATGGTAAAGCAGGCTAGAGTCT TAACCATGGTGCTATTCACTGGGTTTACTTGTTTAACACAAGTTTATACCTGGTGTCAATAAAACAAATA TGTATTTCTTGTCTACTAAGGATTGCCAAGCTTTGTTTTGAATTTCTGTATTGGTCTCTAGGTGTAGCCT TTACTTCCTTTACTGTTGGCGTGTTATGCTCCCAGTTCCCCTATAGAGTCGTCTACACTTCCTCCCTGTG CTCTTCACTGGCCATTTTAGTTATCTGCATTAGAACTCTCACCCCAACCCCCCCAAAACTTTGAACCTAA ATAACCCCTCCCCCATCCTAATCAGAGTCAGCACAGCTTTCCTGTCAGAGGATAGGAACACTTGCTCTTT GAGCCCCGTGACCGACAGTGACCAGGGATTGGCATTCTTGGATTGGCATGCTTTCCATTGTTACTTTGTC TATTTTGGTAAGAAAAACATCAAAGGTCCCCTTGGGAATTTCAAAGGTTGGAAATTATACGTTTATACTT TTATTAGTTTGCTCCAAGTATGACTGTGTTCACTTAAGTTTAGAGAAACACTGGGTTTTGCTAAACTCGG TTAACAAAAGCCACTGGTAACTGAAGGTATTTAAGCTAGGGTCATTTGAAAGCTTCAGCCTCAGAATGTG ACCTTTAGTCAGGGCTGCAGATAAAAATAGGCAGGAATCAAATGACTAAGAATGTAATAGGGAAGAAGTG CCCTGCCTGCCAGCTTGGGAGTGATTTGTACCTGTGTATTTATCCTTGATCATAGTTTGCTTATTTATGT TTAACTCTTCGGACTTCAGAGCACTTTATGTAGTTGAATAAACCCTAGAGGTTGAGGTGACTAAAAGGTT AGCCTCTCATAACCCAGCCATGGAAGTTTTGTTTACTAGGAGCCTGACTTCCCAGCTCACAAAGGGTGAA ATGAAAGCTGAAGTACAGACAGGATCTTAGTAGGTATTTTAGGTCCAGGGCCATGAAGACTTGGAGAGCG CAGTGGCTGGGCAAGGGGCTGCTTTGGAGGGAAGAAGCATGTGGTCTGAGTGCTGACTAGATGAATAGTT GAGGCACATCCTTCAGAGAAGAGGGAGGGGCTGCTTGGAAAGATGGCTCTCAGCAAAATCTGTTTGTCTT ACACGTCTCTCAGGGAAAAAACATGCAGTCTTCAAGCATCTTCCATGTACATTCTATCTGGGTGAACACC TTCATTCTGGTAGAGCACCTAACACTTTAACAGCTGTTCCCGAAAGGGTTAGGACCAACTGCAAGTTAAT GTGGGTTGTAAATGTTCCCCTAACTTCTGTTTCTTCTGAAGAGAAAATAAACTTTTTTCCCCCCAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_008562 |
| Insert Size | 996 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC021638, AAH21638 |
| RefSeq Size | 3464 bp |
| RefSeq ORF | 996 bp |
| Locus ID | 17210 |
| UniProt ID | P97287 |
| Gene Summary | Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 2 has antiapoptotic activity.[UniProtKB/Swiss-Prot Function] |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Angiotensin II degrades myeloid cell leukemia 1 in human umbilical vein endothelial cells
,Zhang, W;Yang, R;Feng, Y;Hu, B;Zhang, J;Zhang, Q;Rong, N;,
IUBMB Life
,PubMed ID 28261909
[MCL1]
|
|
Bok Is Not Pro-Apoptotic But Suppresses Poly ADP-Ribose Polymerase-Dependent Cell Death Pathways and Protects against Excitotoxic and Seizure-Induced Neuronal Injury
,D'Orsi, B;Engel, T;Pfeiffer, S;Nandi, S;Kaufmann, T;Henshall, DC;Prehn, JH;,
J. Neurosci.
,PubMed ID 27098698
[MCL1]
|
|
AMP-activated protein kinase (AMPK)-induced preconditioning in primary cortical neurons involves activation of MCL-1.
,null,
Journal of neurochemistry
,PubMed ID 23199202
[Mcl1]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG204868 | Mcl1 (tGFP-tagged) - Mouse myeloid cell leukemia sequence 1 (Mcl1) |
CNY 5,200.00 |
|
| MR204868 | Mcl1 (Myc-DDK-tagged) - Mouse myeloid cell leukemia sequence 1 (Mcl1), nuclear gene encoding mitochondrial protein |
CNY 3,600.00 |
|
| MR204868L1 | Lenti ORF clone of Mcl1 (Myc-DDK-tagged) - Mouse myeloid cell leukemia sequence 1 (Mcl1), nuclear gene encoding mitochondrial protein |
CNY 6,000.00 |
|
| MR204868L2 | Lenti ORF clone of Mcl1 (mGFP-tagged) - Mouse myeloid cell leukemia sequence 1 (Mcl1), nuclear gene encoding mitochondrial protein |
CNY 6,000.00 |
|
| MR204868L3 | Lenti ORF clone of Mcl1 (Myc-DDK-tagged) - Mouse myeloid cell leukemia sequence 1 (Mcl1), nuclear gene encoding mitochondrial protein |
CNY 6,000.00 |
|
| MR204868L4 | Lenti ORF clone of Mcl1 (mGFP-tagged) - Mouse myeloid cell leukemia sequence 1 (Mcl1), nuclear gene encoding mitochondrial protein |
CNY 6,000.00 |
