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Zfand2b (NM_026846) Mouse Untagged Clone
CAT＃: MC201128
Zfand2b (untagged) - Mouse zinc finger, AN1 type domain 2B (Zfand2b), transcript variant 1, (10ug)
CNY 2,400.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 1110060O18Rik; C81256 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC011495 sequence for NM_026846
AACCTGTGCTGGGCGGGGGAGAGGAAGGGGCGGGGCGGGGAGCCCCCCGGAGTTGCTGTGTTGCGGACGG GGCCCGGAGCGGGAGTCCTTGGCACGCTCAGCTCTCGTTTCTTCCCCGCAGCAGGCCCCGCACGGCCAGG CGATGGAGTTTCCGGACCTCGGGGCTCACTGTTCCGAGCCGAGCTGTCAGCGCTTGGATTTTTTGCCACT CAAGTGCGATGCCTGCTCGGGCATCTTCTGCGCAGACCATGTGGCCTACGCCCAGCATCACTGTGGATCA GCTTACCAAAAGGATATCCAGGTACCTGTGTGCCCTCTCTGTAATGTGCCTGTGCCGGTGGCCAGAGGAG AGCCTCCTGACCGTGCTGTGGGAGAGCACATTGACAGAGACTGTCGTTCTGACCCAGCACAGCAAAAACG CAAGATCTTCACCAATAAGTGTGAACGTTCTGGCTGCCGGCAGCGGGAGATGATGAAACTGACTTGTGAT CGCTGTGGCCGAAACTTCTGCATCAAGCACCGTCATCCCCTGGACCATGAATGCTCTGGGGAAGGTCATC AGACCAGCAGGGCAGGGCTTGCTGCTATTTCTAGAGCACAAGGTCTGGCTTCTACAAGCACCGCCCCCAG TCCAAGCCGGACCTTGCCTTCATCATCCTCCCCAAGCAGAGCTACACCCCAGCTTCCAACCAGGACAGCC TCTCCTGTTATTGCTTTGCAGAATGGCTTGAGTGAGGATGAGGCCCTGCAGCGTGCCCTGGAACTGTCCC TTGCGGAGGCTAAACCCCAGGTTCTAAGTTCTCAGGAGGAAGACGACTTGGCGTTAGCACAGGCACTGTC AGCCAGTGAGGCAGAATACCAACAGCAGCAGGCGCAGAGTCGTAGCTTGAAGCCGTCCAACTGCAGCCTG TGCTAGGGCCCTGGGCTTGGGGAGAGAGGCTCACCCAAGGACTGTGACCCTCACATCTCCAGGGTCCACA GGGAAAGGAAGCACAGAGAAGCCTGGACAGCAGTGCCAAGCAGGAGTGACGTGGAGGACGCTCCATGGAG CCCGGAGAGGAAGGACACTCATGCAGCTAAGCTAGCTCTGCTGCTGCAGAAGAGGGTGGCCGGGAAGTGC TCTCTGGTTGGGGCCTTGGTAGGTGCTAACCAGACTCAATCCCTACAGCCTTTTTCATCATGTTACTCCC TTTTCCCTGGGGCTGCCACATGTAGCAGACAGGGAGAGGGCCGGGAAGAGTAAAGACTGGCAATCAGTAA AAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_026846 |
| Insert Size | 774 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | BC011495, AAH11495 |
| RefSeq Size | 1274 bp |
| RefSeq ORF | 774 bp |
| Locus ID | 68818 |
| UniProt ID | Q91X58 |
| Gene Summary | Plays a role in protein homeostasis by regulating both the translocation and the ubiquitin-mediated proteasomal degradation of nascent proteins at the endoplasmic reticulum (PubMed:24160817, PubMed:26337389, PubMed:26692333). It is involved in the regulation of signal-mediated translocation of proteins into the endoplasmic reticulum (PubMed:24160817). It also plays a role in the ubiquitin-mediated proteasomal degradation of proteins for which signal-mediated translocation to the endoplasmic reticulum has failed (PubMed:18467495, PubMed:26337389). May therefore function in the endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for proteasomal degradation (PubMed:24160817, PubMed:26337389). By controlling the steady-state expression of the IGF1R receptor, indirectly regulates the insulin-like growth factor receptor signaling pathway (PubMed:26692333).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript. All three transcripts encode the same protein. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG203320 | Zfand2b (tGFP-tagged) - Mouse zinc finger, AN1 type domain 2B (Zfand2b) |
CNY 2,850.00 |
|
| MG219158 | Zfand2b (tGFP-tagged) - Mouse zinc finger AN1 type domain 2B (Zfand2b) transcript variant 1, (10ug) |
CNY 2,850.00 |
|
| MR219158 | Zfand2b (Myc-DDK-tagged) - Mouse zinc finger, AN1 type domain 2B (Zfand2b), transcript variant 1 |
CNY 2,400.00 |
|
| MR219158L3 | Lenti ORF clone of Zfand2b (Myc-DDK-tagged) - Mouse zinc finger, AN1 type domain 2B (Zfand2b), transcript variant 1 |
CNY 4,750.00 |
|
| MR219158L4 | Lenti ORF clone of Zfand2b (mGFP-tagged) - Mouse zinc finger, AN1 type domain 2B (Zfand2b), transcript variant 1 |
CNY 4,750.00 |
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