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Cd177 (NM_026862) Mouse Untagged Clone
CAT＃: MC201519
Cd177 (untagged) - Mouse CD177 antigen (Cd177), (10ug)
CNY 5,992.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 1190003K14Rik; Pdp3 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC027283 sequence for NM_026862
AAATTTCCAGCCACAGACTGGTATCATGAATTCTATACCAGTGCTGACCCTTCTGGGGGTCACGGCCTTG CTACCCTGTGTCCCAGCTCTGACCTGCCAGAAAAGCAGCGCACAGGCTGTGAGGAATGTGGCAGAGCTGC CCCTCAGGTGGTGGGGAGCTGGTGAGAAAACCTGCGAGGTTAGCGAGGGTTGCCAAGACTTGATAATGCT CCTGTATAATGGACCCAAGGTCAACTTGGTGATCATCAAGGGCTGCACCGAGGTTGAGGACCAAGAGCCG AAGGTGATCTGGCTCAGGACAGGCCCTGGGCTCTCTGTGGTGTCCTACACCCGTGTGTGTCGCCATGGTG ACCTCTGCAATGATGTGAACAGCACTAAGATCCTTGAGGAGCTACCTACACCCACAGTTCCAGGGTCCCT GCGCTGCCCACTCTGCCTTTCTAATGACAGCTGTGAGAATGCACCGGAGCAGGTCTGCCCTGTGGGAAGC ACACACTGCTACGATGGAGTCCTCAGGCTCAGGGGAGATGGCATCAGGACCAATCTCAAGGTGCAGGGCT GCATGGCCCAGCCAGACTGCAACCTGCTTAATGGCACCCAGGCGATTGGGACCTTGTATATGAGCGAAAA CTGTGATCTTATAGGTCCACAGGCTCTGGATTGCAATAGTGGGAGCTTGGAAACTGTGAGGAATGTATCA GATCTGCACTTGAGCTGGACGACTGGCTGGCAAACCTGTGAGGCTGGCGAGGGGTGTTATGAAACAGTGA TGCTAATACAAAATGGACATGAATTTCACATGGTTCTCACTAAGGGATGTACTAGGGATATGAACAAAAA GGCTCGGCTCACCAGGCATAGAACAGGCCCAGGGATCTCCATCGTCTCCTACGTGCATGTGTGCCGCGAC AGGGACTTCTGTAATGACCTGTCTACAACAGACCCTCTTTGGACCCCGCCCCCTGACACAGAGCTAGGGA CCCTGCGCTGCCGACACTGCCTTTCAACCGGCAGCTGTGTGAGTGCATCCGAGCTGGTCTGCCCCGCAGG CAGCACACACTGCTACAGTGGAGTCCTCAGCCTCAGGGGAGGAGGGGTCATTTCTGATCTGAAGGTACAG GGATGCATATCGCAGTCCCAGCCAGGATGCAACCTGCTCAACGGTACCCAGACAATCGGACCCGTGGATG TGCGTGAGGACTGCGGTCTTCAGTTAGATGCTCTGAAATGCCAGCATGGGACGCTGAAGACCATCCAGGA TATATCGAAGCTGCCTCTCCAGTGGACGGCTGGCCAGAAAATCTGTAATGTGGGTGAAGGCTGCCAAGAC ACACTGATGTTGATAGAGAACGGAGAGCAGGTGAACTTGGTTCTCACGAAAGGCTGCACTACCGCAAAGG ACCAAGAGGCCAAAGTCACGGAGCACAGAACTGGACCAGGGCTGTCTGTCACCTCCTACACCCGAGTGTG CCGTAAAAAAGACTTCTGCAATGACCTGTCTACCACAGCCCCTCTCTGGGCTCCACCTCCAGTGACAGCC CCAGGGACCACTCGCTGCCCTCTCTGCTTTTCTGAACAAGCCTGTGAGAATGCACCGGAGCAGGTCTGCC CTGCAGGCAGCACACACTGCTACAGTGGAGTCCTCAGCCTCAGGGGAGGAGGGATCATCTCTGATCTGAA GGTGCAGGGCTGTATGTCCCAGCCAGGATGCAACCTGCTCAACGGTACCCAGACAATCGGACCCGTGGAT GTGAGCGAGCGCTGCAGTCCTCCGTCAGAAACAACAGAGTTGTCCTGTTACAGGGGTGTGATGTTTGAGC TTGGCAATGGCTTTGCGGAGGAACCTGTCAAGTGGACGGCACCAGGGTCTCAGGTGTGTGCACCTGATGA GATTTGTCAAGAGACGCTGCTGCTCATAGACGTAGGACAAAAATCAGCCTTCCTGGGGAGTAAAGGCTGC AGCAGTCCTGGGGCGCAGGACAATATTGGTGTCTCCATATTCTCCCGGCTCCCTGGGATGCTGGTAGCTT CCTATACCAAATTCTGTTCTTCCCACCTGTGCAATGGAGCCGACAGCAGCAGTGTCCTTCTAAGCATCCT CCCTCGTCCAGATGTTCCTCCCCCAGGAGATGTGCAGTGCCCCATGTGTGTAGAGTTATTTGGATCCTGC AAGAGCACTGACTCTGTCACCTGCCCTAGGGGTGCCACTCACTGTTATAAAGGTGACATTGCACTACAGG GAGGTGGACTGACTACCAGAGTGAGCATTCAGGGGTGCATGGCCCCACCTATCAAACCTTTACTGGGTGA CTCCAAAACAATCGGTATCTTCTCGGCAGAGGAGAGCTCTAACTATCGACATGAGGATGATGTTACCTCG GCCCCTTCCCTGGCCTGGACCTTACGGCTATCGGCCTGGATGTTAGGGCTATCGGCTCTTCTCAGCTCTT TGTATGCTGGGATCTGTCCTCTCTGCTGAACCCATTTCCTGACCATTCTTAATCCCTCTTGGCCACCCAG ACCCAGCCCTCCTCTGACTTCAAAGACCTGAGGCTGGGCGCTGTCGGCCTGCGCTGTCGGGCGCCCTCAT CCCTCACCCACACACCTCTGCCCCTCATGCTTAGACTTGGGAGCCACTGAACCCAGCCGGCTCCAGAGCA GACAAGCACACGTTGACCACGTGTGGAAAAATAAAGTTGCTGTTGTTTGTCCAAAAAAAAAAAAAAAAAA AAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_026862 |
| Insert Size | 2454 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC027283, AAH27283 |
| RefSeq Size | 2733 bp |
| RefSeq ORF | 2454 bp |
| Locus ID | 68891 |
| UniProt ID | Q8R2S8 |
| Gene Summary | In association with beta-2 integrin heterodimer ITGAM/CD11b and ITGB2/CD18, mediates activation of TNF-alpha primed neutrophils including degranulation and superoxide production (By similarity). In addition, by preventing beta-2 integrin internalization and attenuating chemokine signaling favors adhesion over migration (By similarity). Heterophilic interaction with PECAM1 on endothelial cells plays a role in neutrophil transendothelial migration in vitro (By similarity). However, appears to be dispensable for neutrophil recruitment caused by bacterial infection in vivo (PubMed:25359465). Acts as a receptor for the mature form of protease PRTN3 allowing its display at the cell surface of neutrophils (By similarity). By displaying PRTN3 at the neutrophil cell surface, may play a role in enhancing endothelial cell junctional integrity and thus vascular integrity during neutrophil diapedesis (By similarity).[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
CD177-mediated nanoparticle targeting of human and mouse neutrophils
,null,
PLoS ONE
,PubMed ID 29990379
[Cd177]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MR210799 | Cd177 (Myc-DDK-tagged) - Mouse CD177 antigen (Cd177) |
CNY 5,992.00 |
|
| MR210799L3 | Lenti ORF clone of Cd177 (Myc-DDK-tagged) - Mouse CD177 antigen (Cd177) |
CNY 9,120.00 |
|
| MR210799L4 | Lenti ORF clone of Cd177 (mGFP-tagged) - Mouse CD177 antigen (Cd177) |
CNY 9,120.00 |
