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Hdac4 (NM_207225) Mouse Untagged Clone
CAT＃: MC202651
Hdac4 (untagged) - Mouse histone deacetylase 4 (Hdac4), (10ug)
CNY 11,248.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 4932408F19Rik; HD4 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC066052 sequence for NM_207225
CGGGCCTCCTCAATTTTGTTCCTGCATGTGCTGGTGGAAATTTGGAGTGTGTTGGAGCCACTGTTTACCT GGACATCTTGAGCCATTTTGAACTTAAGGCACTGACGCTGCTAGCAATGAGCTCCCAAAGCCATCCAGAT GGACTTTCTGGCCGAGACCAGCCTGTGGAGCTGCTGAATCCTGCCCGTGTGAACCACATGCCCAGCACGG TGGACGTGGCTACAGCGCTGCCTCTGCAAGTGGCCCCTACAGCAGTACCCATGGACCTGCGCTTGGACCA CCAGTTCTCACTGCCCTTGGAACCTGCATTGCGGGAGCAGCAACTGCAGCAGGAACTCCTAGCACTGAAA CAGAAGCAGCAGATCCAGCGGCAGATACTCATTGCAGAGTTCCAGCGTCAACATGAGCAGTTGTCCCGAC AGCATGAGGCACAGTTGCATGAACATATCAAGCAGCAGCAGGAGATGCTGGCCATGAAGCACCAGCAGGA GCTGCTGGAGCACCAGCGGAAACTGGAGCGGCACCGGCAAGAGCAGGAGCTGGAGAAGCAGCACCGTGAG CAGAAGCTGCAGCAGCTCAAGAACAAGGAGAAGGGCAAAGAGAGTGCTGTGGCGAGCACAGAGGTGAAGA TGAAGCTGCAGGAGTTTGTTCTCAACAAGAAGAAGGCTCTAGCCCACCGGAACCTGAACCACTGCATTTC CAGCGATCCCCGCTACTGGTATGGGAAGACACAGCACAGCTCCCTTGACCAGAGCTCTCCACCCCAGAGT GGGGTGTCAGCCTCCTACAACCACCCCGTCTTGGGAATGTACGACGCCAAAGATGACTTCCCTCTTAGGA AAACAGCTTCTGAACCTAACCTGAAATTACGCTCAAGGCTTAAGCAGAAAGTAGCTGAGAGACGGAGCAG CCCCCTGTTGCGCAGGAAAGATGGCCCTGTGGCCACTGCTCTAAAAAAGCGACCCCTGGATGTTACAGAC TCCGCATGCAGCAGCGCCCCTGGCTCCGGTCCCAGCTCTCCAAATAGCAGCTCTGGCAACGTCAGCACTG AGAATGGCATCGCACCCACTGTGCCCAGCGCTCCAGCTGAGACGAGCTTGGCACACAGACTTGTGACTCG AGAAGGCTCAGTCGCCCCACTTCCTCTCTACACGTCACCATCCTTACCCAACATCACCTTGGGACTTCCT GCCACTGGCCCTGCCGCTGGTGCGGCAGGTCAGCAGGATGCTGAGAGGCTTGCTCTCCCAGCTCTCCAGC AGCGGATCTTGTTCCCTGGGACCCACCTCACCCCGTACCTGAGCACCTCGCCCCTGGAGAGGGACGGTGC AGCAGCTCACAACCCCCTCCTGCAGCACATGGTCCTGCTGGAGCAGCCACCCACCCAGACACCCCTTGTC ACAGGCCTGGGGGCGCTGCCCCTCCACTCACAGTCCCTGGTTGGTGCGGACAGGGTGTCCCCATCCATTC ACAAGCTGCGGCAGCACCGCCCTCTGGGGCGCACGCAGTCAGCACCCCTGCCGCAGAACGCACAGGCCCT GCAGCACCTGGTGATCCAGCAGCAGCACCAGCAGTTCCTGGAGAAGCACAAGCAACAGTTCCAGCAGCAG CAGCTGCACCTCAGCAAGATAATCTCCAAACCTAGTGAGCCACCTCGGCAGCCTGAGAGCCACCCAGAGG AGACAGAGGAGGAGCTCCGTGAGCACCAGGCCTTGCTGGATGAGCCCTACCTAGATCGGCTACCTGGGCA GAAGGAGCCCTCCCTGGCTGGTGTGCAGGTGAAGCAGGAGCCCATTGAGAGTGAGGAGGAAGAAGCGGAG GCCACTCGAGAGACAGAGCCCGGCCAGCGCCCAGCCACTGAGCAGGAGCTGCTCTTCAGACAGCAAGCCC TCCTACTGGAGCAGCAGAGGATCCACCAGTTAAGAAACTACCAGGCATCTATGGAGGCTGCTGGCATCCC TGTGTCATTTGGCAGCCACAGACCTCTGTCTCGGGCACAGTCCTCCCCAGCATCTGCCACCTTCCCCATG TCAGTCCAGGAGCCCCCCACCAAGCCAAGGTTCACCACAGGTCTTGTGTATGACACACTGATGTTGAAGC ATCAGTGCACCTGTGGGAACACCAACAGCCACCCGGAGCATGCTGGGAGGATCCAGAGCATCTGGTCCCG CCTGCAGGAGACTGGACTCCGTGGCAAGTGTGAGTGCATCCGTGGACGCAAGGCCACATTGGAGGAGCTG CAGACAGTGCACTCGGAGGCCCACACACTCCTCTACGGCACAAATCCTCTCAACAGACAGAAACTGGACA GCTCGCTGACCTCAGTGTTCGTCAGGCTTCCTTGTGGTGGTGTTGGGGTGGATAGCGACACCATATGGAA TGAGGTGCACTCGTCTGGGGCAGCCCGCCTGGCTGTAGGCTGTGTAGTGGAGCTGGTCTTCAAGGTGGCC ACGGGAGAGCTAAAGAATGGCTTTGCTGTGGTTCGTCCCCCAGGACACCATGCCGAGGAGAGCACACCCA TGGGTTTCTGCTACTTTAACTCCGTGGCAGTTGCAGCCAAACTTCTCCAGCAGAGGCTGAATGTGAGCAA GATCCTCATTGTAGACTGGGATGTACATCATGGGAATGGGACCCAGCAGGCCTTCTACAATGACCCCAAT GTTCTCTACATGTCCCTGCACCGCTATGACGATGGGAACTTCTTCCCAGGAAGTGGAGCACCAGATGAGG TGGGCACAGGGCCAGGCGTGGGTTTCAATGTCAACATGGCTTTCACGGGTGGCCTCGAACCCCCCATGGG AGACGCTGAGTACTTGGCAGCCTTCAGAACGGTGGTTATGCCTATCGCAAATGAGTTTGCCCCAGATGTG GTACTGGTGTCATCGGGCTTCGATGCTGTGGAGGGCCACCCCACACCTCTTGGAGGGTACAATCTCTCTG CCAAATGTTTTGGGTACTTGACAAAACAGCTGATGGGCTTAGCTGGTGGCCGGCTTGTGCTGGCCCTTGA GGGAGGCCATGACCTGACAGCCATCTGTGATGCTTCTGAAGCCTGCGTGTCTGCTCTGCTGGGAAACGAG CTTGAGCCTCTGCCAGAAAAGGTTCTACATCAGAGACCCAATGCCAATGCTGTCCACTCCATGGAGAAAG TGATGGACATCCACAGCAAGTACTGGCGCTGCCTGCAGCGTCTGTCCTCCACGGTGGGGCACTCTCTGAT TGAGGCGCAAAAGTGTGAGAAGGAAGAAGCTGAGACAGTCACCGCCATGGCCTCGCTGTCTGTAGGCGTC AAACCTGCTGAGAAGAGATCTGAGGAGGAGCCCATGGAGGAGGAACCACCACTGTAGCCCGAAGCTGCTG TTCTCTCCTTTGTTTGTCTGTCTTGAAGCTCAGCCAAGAAACTTACCCGTATCACTCCTGCGTCCTGCCT TGGTGCTCTCTTGAGTACAAAGGGACAGCAGGCGTGCAGCAGCAACGGGAAGCCTTTCTGCCGCCCTGGA CCACAGGTCTGGAGACGCACACGGAACACCGGGTGTGGCAGATCACATGGAACACAGGACAGCGCGCAAC ACACGGGCACACAGACATGTGGAAGCCAAGCACACGCTGGTGGCTCCCCCTCCCCCTGGGAAGCCTCGAA GGAAGAAGCTTGTGGCAACTTGGGCAGAGTTGCTGAATCAAGTTGACATGAGGAAAATGAAAATCAAAGA TCTAATAATACAGAACAAACTTGATTAAAACTGGTGCTTAACATTTGATTCTTACCCACAATCCCACAGT CTCCGTGTAAACCACTCAACTCATCTTGTAGCTTTTTTTTTTTTTTAAACGAAAACAAAACCATTTTCTA TGGCTCTGGCCTGCCTTGTGAACCTTAGTGGGGTGCTGTGGGGGTTCACAGCTTAGTGAGGGACAGAGTT GGAAGAAAGTTTAAACGAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | AscI-NotI |
| ACCN | NM_207225 |
| Insert Size | 3231 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC066052, AAH66052 |
| RefSeq Size | 3960 bp |
| RefSeq ORF | 3231 bp |
| Locus ID | 208727 |
| UniProt ID | Q6NZM9 |
| Gene Summary | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Deacetylates HSPA1A and HSPA1A at 'Lys-77' leading to their preferential binding to co-chaperone STUB1.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG211598 | Hdac4 (tGFP-tagged) - Mouse histone deacetylase 4 (Hdac4) |
CNY 12,848.00 |
|
| MR211598 | Hdac4 (Myc-DDK-tagged) - Mouse histone deacetylase 4 (Hdac4) |
CNY 11,248.00 |
|
| MR211598L3 | Lenti ORF clone of Hdac4 (Myc-DDK-tagged) - Mouse histone deacetylase 4 (Hdac4) |
CNY 13,648.00 |
|
| MR211598L4 | Lenti ORF clone of Hdac4 (mGFP-tagged) - Mouse histone deacetylase 4 (Hdac4) |
CNY 13,648.00 |
