Clu (NM_013492) Mouse Untagged Clone
CAT#: MC203543
Clu (untagged) - Mouse clusterin (Clu), (10ug)
CNY 5,488.00
Cited in 2 publications. |
Product images
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | A; AI893575; ApoJ; C; Cli; D14Ucl; D14Ucla3; Sg; Sgp; Sgp-2; Sgp2; SP-; SP-40; Sugp; Sugp-2 |
Vector | PCMV6-Kan/Neo |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>BC075668
CCAGGAGGAGCGCACTGGAGCCAAGCCGCAGACCGGACTCCAGATTCCAAGGAGGCCACGCCATGAAGAT TCTCCTGCTGTGCGTGGCACTGCTGCTGATCTGGGACAATGGCATGGTCCTGGGAGAGCAGGAGGTCTCT GACAATGAGCTCCAAGAACTGTCCACTCAAGGGAGTAGGTATATTAATAAGGAGATTCAGAACGCCGTCC AGGGAGTGAAGCACATAAAAACTCTCATAGAAAAAACCAACGCAGAGCGCAAGTCCTTGCTCAACAGTTT AGAGGAAGCCAAGAAGAAGAAAGAGGATGCTCTGGAGGACACTAGGGATTCTGAAATGAAGCTGAAGGCA TTCCCGGAAGTGTGTAACGAGACCATGATGGCCCTCTGGGAGGAGTGCAAGCCCTGCCTGAAGCATACCT GCATGAAGTTCTATGCACGTGTCTGCAGGAGCGGCTCAGGGCTGGTCGGCCAGCAGCTAGAGGAGTTTCT AAACCAGAGCTCACCCTTCTACTTCTGGATGAACGGCGACCGCATCGACTCCCTGCTGGAGAGTGACCGG CAGCAGAGCCAAGTCCTGGATGCCATGCAGGACAGCTTTGCTCGGGCATCTGGCATCATAGACACGCTCT TTCAGGACCGGTTCTTCGCCCGTGAGCTTCATGACCCCCACTACTTCTCCCCCATCGGCTTCCCACACAA GAGGCCTCATTTCTTATATCCCAAGTCCCGCTTGGTCCGCAGCCTCATGTCTCCCTCCCACTATGGGCCT CCGAGCTTCCACAACATGTTCCAGCCTTTCTTTGAGATGATCCACCAGGCTCAACAGGCCATGGATGTCC AGCTCCACAGCCCAGCCTTCCAGTTCCCAGACGTGGATTTCTTAAGAGAAGGTGAAGATGACCGCACTGT GTGCAAGGAGATCCGCCGCAACTCCACAGGATGCCTGAAGATGAAGGGCCAGTGTGAAAAGTGCCAGGAG ATCTTGTCTGTGGACTGTTCAACCAACAATCCTGCCCAGGCTAACCTGCGCCAGGAGCTGAACGACTCGC TCCAGGTGGCCGAGAGGCTGACAGAGCAGTACAAGGAGCTGCTGCAGTCCTTCCAGTCGAAGATGCTCAA CACCTCATCCCTGCTGGAGCAGCTGAACGACCAGTTCAACTGGGTGTCCCAGCTGGCTAACCTCACACAG GGCGAAGACAAGTACTACCTTCGGGTCTCCACCGTGACCACCCATTCCTCTGACTCAGAGGTCCCCTCCC GTGTCACTGAGGTGGTGGTGAAGCTGTTTGACTCTGACCCCATCACAGTGGTGTTACCAGAAGAAGTCTC TAAGGATAACCCTAAGTTTATGGACACAGTGGCGGAGAAGGCGCTACAGGAATACCGCAGGAAAAGCCGT GCGGAATGAGATAGAAGCATCACCTTCCTATATGTAGGAGTGTCTGGGAGGGAATCTCCCAGCTCCCCGA GGTGGCTGCAGACCCCTATAGAACTCCACATGTCTCCAGGCGAGTAGGCCTCACCCAAGCAGCCTGCCCT TCCTCTGGATTCTGTACACTAATGCCTGCACTTGCTGCTCTCGGGAAGAACTGATTCCCCCACGCAACTA ATCCAATAAAAGCCGCCTTGCGATACGTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAA |
Restriction Sites | AscI-NotI |
ACCN | NM_013492 |
Insert Size | 1347 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | BC075668, AAH75668 |
RefSeq Size | 1684 bp |
RefSeq ORF | 1347 bp |
Locus ID | 12759 |
UniProt ID | Q06890 |
Gene Summary | The protein encoded by this gene is a secreted chaperone that can, under some stress conditions, also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. The encoded preproprotein undergoes proteolytic processing to generate a disulfide-linked heterodimeric mature protein comprised of alpha and beta subunits. Mice lacking the encoded protein exhibit increased severity of autoimmune myocarditis, faster progression of the acute inflammation to myocardial scarring and decreased brain injury following neonatal hypoxic-ischemic injury. [provided by RefSeq, Nov 2015] |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
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Clusterin and FOXL2 Act Concordantly to Regulate Pituitary Gonadotroph Adenoma Growth
,Vera Chesnokova, Svetlana Zonis, Kolja Wawrowsky, Yuji Tani, Anat Ben-Shlomo, Vladimir Ljubimov, Adam Mamelak, Serguei Bannykh, and Shlomo Melmed,
Mol. Endocrinol., Dec 2012; 26: 2092 - 2103.
[CLU]
|
PCSK9 reduces the protein levels of the LDL receptor in mouse brain during development and after ischemic stroke
,null,
Journal of Lipid Research
,PubMed ID 21518694
[Clu]
|
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MR207148L4 | Lenti ORF clone of Clu (mGFP-tagged) - Mouse clusterin (Clu) |
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