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Relb (NM_009046) Mouse Untagged Clone
CAT＃: MC203717
Relb (untagged) - Mouse avian reticuloendotheliosis viral (v-rel) oncogene related B (Relb), (10ug)
CNY 4,160.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | shep |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC019765
GCCCGCCGCCCGCTCGGCCCGGCGCCCCCCGCAGCCCCGGGCGCCGTGCGTCCAGCCCGGCCTTCGGCCC TAGCCTTGCACCGCTTGCCCGGCCGGTGATCGTCCCAGCCGACCGGGCTGTCCGACTGCCCGGCTTGCCC TCGTGTGCGCTCGCCCTGAGCTGGCCTTCGGGCTGTCGGTCCCTACGGGCCGGGCCATGCCGAGTCGCCG CGCTGCCAGAGAGTCCGCGCCCGAGCTAGGGGCCTTGGGTTCCAGTGACCTCTCTTCCCTGTCACTAACG GTCTCCAGGACCACAGATGAATTGGAAATCATCGACGAATACATTAAGGAGAACGGCTTTGGCCTGGACG GGACACAGCTGAGTGAGATGCCGCGCCTGGTGCCCCGCGGGCCCGCCTCACTGAGCAGCGTCACGCTGGG CCCTGCTGCACCACCGCCTCCGGCCACGCCGTCCTGGAGCTGCACACTGGGCAGGCTGGTGTCACCCGGC CCGTGCCCACGGCCGTACCTGGTCATCACAGAGCAGCCAAAGCAGCGTGGCATGCGCTTCCGCTACGAGT GCGAGGGCCGCTCGGCCGGCAGCATCCTCGGGGAGAGCAGCACCGAAGCCAGCAAGACCCTGCCCGCCAT CGAGCTTCGAGACTGTGGCGGGCTGCGGGAGGTGGAGGTGACGGCGTGCCTGGTGTGGAAGGACTGGCCA CACCGGGTACACCCACATAGCCTCGTGGGGAAAGACTGCACGGACGGCGTCTGCAGGGTGCGGCTGCGGC CTCACGTCAGCCCCCGGCACAGCTTTAACAACCTGGGCATCCAGTGTGTTAGGAAGAAGGAAATTGAAGC TGCCATTGAGCGGAAGATCCAGCTGGGAATTGACCCCTACAATGCTGGCTCCCTGAAGAACCATCAGGAG GTCGACATGAATGTCGTCAGGATCTGCTTCCAGGCCTCCTATCGGGACCAGCAGGGACATCTGCACCGCA TGGACCCCATCCTCTCTGAGCCTGTCTACGACAAGAAGTCCACCAACACATCGGAGCTGCGGATTTGCCG AATCAACAAGGAGAGCGGGCCGTGCACAGGTGGTGAGGAGCTGTACTTGCTCTGTGACAAGGTGCAAAAA GAGGACATATCCGTGGTGTTCAGCACAGCTTCCTGGGAAGGCCGTGCCGACTTCTCTCAAGCTGATGTGC ACCGGCAGATCGCCATTGTGTTCAAAACGCCACCCTACGAGGACCTGGAGATCTCAGAGCCCGTGACTGT CAATGTGTTCTTGCAGCGGCTCACGGATGGGGTGTGCAGCGAGCCGCTGCCCTTCACGTACCTGCCTCGG GATCATGACAGCTACGGTGTGGACAAGAAGCGAAAGCGGGGACTGCCTGATGTCCTTGGAGAGTTGAGCA GCTCTGATCCACATGGAATCGAGAGCAAACGAAGGAAAAAGAAACCAGTGTTCTTGGACCACTTCCTGCC TGGCCACAGCTCAGGCCTGTTCCTCCCACCATCGGCTCTGCAGCCGGCAGACTCTGATTTCTTCCCTGCT TCCATATCCCTTCCTGGGCTGGAGCCTCCTGGTGGACCCGATCTCCTGGACGATGGCTTTGCCTATGATC CTTCTGCCCCCACGCTCTTCACTATGTTGGACCTGCTGCCCCCAGCACCACCACTTGCCAGTGCTGTGGT GGGTAGCGGGGGTGCAGGGGCCACCGTTGTGGAGTCTTCTGGCCCAGAGCCCCTATCACTGGACTCTTTT GCAGCGCCGGGCCCCGGGGATGTTGGTACTGCTAGCCTTGTGGGCAGCAACATGTTTCCCAACCAGTACC GAGAGGCAGCTTTCGGGGGTGGCCTCCTATCTCCAGGGCCTGAAGCCACGTAGCCTCTGAGGTAACAGAG GAGGCACTGGGTGAGGTATGTGGTATAGCACTCCATTCCGAAGCCAACCTTGATCAGTCTTCCAGCTTCC TCATCCTGAATCGGACATCTGCAGCGCTGGTGGGAAGATGGGGAGCACTCCGGTTCTCTTTGAGCCCATT TTACAGAATGCTGAGTCCGAAGAGGAAAAGGGGCTCCTGCAGATGGACCCCTTCTCAGGACAGATTCTCA GAGATTGTACATAGGGGAGGAGGGAGCAGGTCCCCAGCCTTCTCCCCTAATCCTGAAGAAGGCAGTGGAT TGTTCAGTTTTCCCAATAAAAATTAGTTTTTTGAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_009046 |
| Insert Size | 1677 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC019765, AAH19765 |
| RefSeq Size | 2218 bp |
| RefSeq ORF | 1677 bp |
| Locus ID | 19698 |
| UniProt ID | Q04863 |
| Gene Summary | NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. NF-kappa-B heterodimeric RelB-p50 and RelB-p52 complexes are transcriptional activators. RELB neither associates with DNA nor with RELA/p65 or REL. Stimulates promoter activity in the presence of NFKB2/p49 (By similarity). As a member of the NUPR1/RELB/IER3 survival pathway, may allow the development of pancreatic intraepithelial neoplasias. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer in a CRY1/CRY2 independent manner. Increased repression of the heterodimer is seen in the presence of NFKB2/p52. Is required for both T and B lymphocyte maturation and function (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG208842 | Relb (tGFP-tagged) - Mouse avian reticuloendotheliosis viral (v-rel) oncogene related B (Relb) |
CNY 5,760.00 |
|
| MR208842 | Relb (Myc-DDK-tagged) - Mouse avian reticuloendotheliosis viral (v-rel) oncogene related B (Relb) |
CNY 4,160.00 |
|
| MR208842L3 | Lenti ORF clone of Relb (Myc-DDK-tagged) - Mouse avian reticuloendotheliosis viral (v-rel) oncogene related B (Relb) |
CNY 6,460.00 |
|
| MR208842L4 | Lenti ORF clone of Relb (mGFP-tagged) - Mouse avian reticuloendotheliosis viral (v-rel) oncogene related B (Relb) |
CNY 6,460.00 |
