Cldn2 (BC015252) Mouse Untagged Clone
CAT#: MC206508
Cldn2 (untagged) - Mouse claudin 2 (cDNA clone MGC:18348 IMAGE:4223446), (10ug)
CNY 2,400.00
货期*
现货
规格
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经常一起买 (3)
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | AL022813 |
Vector | PCMV6-Kan/Neo |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>BC015252
GAAAGAAGTCAGCTTGCCAGAGACACTGTGAAATAAGGGATTAGAGGCTCGGATCCAAGAAGCAAGAGCA GCAGCCAAACGACAAGCAAACAGGCTCCGAAGATACTTCTACTGAGAGGTCTGCCATGGCCTCCCTTGGC GTTCAACTGGTGGGCTACATCCTAGGCCTTTTGGGGCTGTTAGGCACATCCATTGCCATGCTGCTTCCCA ACTGGCGAACGAGTTCCTATGTTGGTGCCAGCATTGTGACGGCGGTTGGCTTTTCCAAGGGCCTCTGGAT GGAGTGTGCGACACACAGCACAGGCATCACCCAGTGCGATATCTACAGTACCCTTTTAGGACTTCCTGCT GACATCCAGGCTGCCCAGGCCATGATGGTGACGTCCAGTGCAATGTCCTCGCTGGCTTGTATTATCTCTG TGGTGGGCATGAGATGCACCGTGTTCTGCCAGGATTCTCGAGCTAAGGACAGAGTGGCTGTAGTGGGTGG AGTCTTTTTCATCCTTGGTGGCATCCTGGGCTTTATCCCAGTTGCTTGGAATCTTCATGGCATCCTTCGG GACTTCTACTCGCCGCTGGTTCCTGACAGCATGAAATTTGAGATTGGAGAGGCTCTGTACTTGGGCATCA TCTCAGCCCTGTTTTCTTTGGTAGCCGGAGTCATCCTTTGCTTTTCCTGCTCGCCCCAGGGCAATCGTAC CAACTACTATGATGGCTACCAGGCCCAGCCTCTTGCCACTAGGAGCTCTCCAAGATCTGCTCAACAGCCC AAAGCCAAGAGTGAGTTCAACTCATACAGCCTGACTGGGTATGTGTGAAGAACCAGGGGCCAGAGCTGGG GGTAGGGTGGGGTAGTGGCTGGGACTATATATATAAAAAAAAGCAGTGGACAATGCCCCCAGGGTCACAA GCAAAGGACATTGCCACTGAATCATGTGTAAGGTGCTGCTGAGGGTAGAATGACTTTGGCCATTGGATGG AGTGAAGGCAGAGATGAGAAGAGGGGTGTCAGCATGTAGATGGCATTGCCAAGGACGCTTGCCAAGCTAG CTTTTCTATTTCCCTCACCTGACCTCACTAAAGTACCTCCTGTGCTTTGAATGCTCAACCCAAAAGCCCA AATCCCATCTCTGCCACTTTAGGCTATGCCCAGAGGCTCTCTTCTGCCCTTTGGTTTACTTGGAGATCTG TCCCCAAACCAATCATATCCTGTTGACTAATCACCTGTGATCAAAAGACCCTCTCCCTCTGGCTGAGGTT GGCTCTTAACTCAATTACTAAGGGACAGAGAGAAGAAAGAGTGGTGGCTTCTGTGAGGACATTTCTAGCT CCCTTCTCAAATCTCCAGCCAAAGAAATGGATTAGTCAGTAATGGGCCCTGAAGCTTCTCTTCCAGTTTT GCTATGAATGCAGTATGTCCAGACTGCATTGTGAATGAACTGAAGGAAAGCTATCTCATGGCATCCAGCA GAATACAGCTGGGTGCAGGATGGGAGGCAACCTGGGATCTAAAGAAACAAAACAAACAGCAAAACCCGAC AGAATCCCTTCTCAGGCCATCTCCTATAATTCCCGTACATTTGTGGGTCAGGGATGGAAGCACTGCTAAG GAAAGCACAAGAAGCCAAGGGAAAGCACATGGCTGCTGCCCTCTGACTCCACAGAGGAATTGCCCAGAAG CCAAGGTGAACACGGACCACTGAAAGCTCTGCCTCCCACTGGGGTGTCTGACCCAGCTTCCTGCTAAACC ACAAGACTTGGAGCCCTAGACAAGGGTTTCCTTAAGGACAATAAACCAGTTTTTCTAGAACTGCCCTTTG ACATGCGAGTTGCAGAAGGCTTAAAAAAAATACTACCCTTTAGCCCTGACCGAGAAAGAATAAGGGCTTG GGTATCAAAGAACCGGACAGAGATGTGTGGTAGCTGTTATGTGTGCTCCTACTGTTTCAGAGAGGCAGCC CTACCAGATACTTTAGACTTGATGGAAGACCAACCCATCAGGGTCTATGTCTCAGCACTACAGAGCCTCT GAAAGACCACAGCACCAGAGAGGTCCTTTGTCACTTTTCACACTTGAGTCATCGCCCATCAGAAGATATT CTCACAGGTATGCAAAGTCTCCAGTGTGGAACATCTGTGACCAAGGTGTTGTGTTCATGACCTGAGCAAT TGGTGAACTTCTGCCTGGGATTGTGCTTGAGGTGGGAGAACGGAGACTGGTTCCCTGTCCAACAGTTTTA TTTCCACGGTCTTAAAATGCTCCATTTCTTCTGTGGTAGATGGGGGTCATAAACCAGAGACATTTCCCCA CCACCAGCAGCTTAATATCACCAGCTTCAGAAGATCCCCAGCGCACCTCATCAAAACTTCAGCACCGGCA AGAGAGGCCCATATGTGAGGTTTCCCTTAACATGCCTTTCCTATTTCCACCATATTACTTGTGTTCAAGC TGATATGCTGACCTGGAAGCCATTTCCTTTTAACTAAGTCATCCCCATGCTTGGAGAACTTGCTCATTGA GCCTTCTCTGACCACTCCTTCCTGTTCTTTCCTTTCCCTCCTCCAACTCCCAATATATAAATTGCCTAAT CCTCATCATTCATAATTTTGATTGATAGTTTATAGTTCTTGTATGTGCATTTGTGTGTGACTCTATCCGT CTGTCTGTCTGTGTGATCTCAAAAGTTCACTGTAAGTACTTGGAGGGCAATTGCTATATCTTAGACCTGT CCATATGTATACCCAAGACTGTAACAGTGCTGGGCACACACAAGGTGATCAATAAACGGATGTTGATTGA GTAAAAAAAAAAAAAAAAAAAAAAAAAA |
Restriction Sites | EcoRI-NotI |
ACCN | BC015252 |
Insert Size | 693 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | BC015252, AAH15252 |
RefSeq Size | 2828 bp |
RefSeq ORF | 693 bp |
Locus ID | 12738 |
Gene Summary | This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The knockout mice lacking this gene display normal appearance, activity, growth and behavior, but are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules. The proteins encoded by this gene and another family member Cldn12 are also critical for vitamin D-dependent Ca2+ absorption between enterocytes. [provided by RefSeq, Aug 2010] |
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