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Cd33 (NM_001111058) Mouse Untagged Clone
CAT＃: MC208244
Cd33 (untagged) - Mouse CD33 antigen (Cd33), transcript variant 1, (10ug)
CNY 5,488.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | gp67; Siglec-3 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC208244 representing NM_001111058
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCTGTGGCCACTGCCGCTGTTCTTGCTGTGTGCAGGCTCCCTGGCTCAGGATTTAGAATTCCAGCTGG TGGCGCCCGAGTCAGTGACAGTCGAGGAGGGCCTATGTGTCCATGTGCCCTGCAGTGTTTTCTACCCCTC CATTAAGCTCACTTTAGGACCTGTGACCGGCTCCTGGCTCCGGAAAGGGGTCAGTCTCCATGAAGACTCT CCAGTGGCCACAAGTGACCCCAGACAACTAGTGCAGAAGGCAACACAGGGCAGATTCCAACTCCTTGGGG ACCCACAGAAACATGACTGTTCCCTGTTCATCAGAGATGCACAGAAAAATGACACAGGAATGTACTTCTT CAGAGTGGTCAGAGAACCTTTTGTGAGATATTCTTACAAAAAAAGCCAGCTGTCACTGCATGTGACCTCT CTATCACGGACTCCTGACATTATAATCCCGGGGACCCTGGAGGCTGGCTATCCTAGCAATCTCACCTGCT CTGTGCCCTGGGCTTGTGAGCAGGGGACACCCCCTACTTTCTCCTGGATGTCAACTGCCCTCACCTCCTT GAGTTCCCGAACCACAGACTCCTCCGTGCTGACGTTCACACCTCAGCCTCAGGACCATGGTACCAAACTC ACCTGCTTGGTGACCTTCTCTGGAGCAGGTGTCACTGTGGAAAGGACCATCCAGCTCAATGTTACCCGGA AATCAGGCCAGATGAGAGAGCTGGTCCTGGTGGCTGTGGGGGAGGCAACGGTCAAGCTCCTGATTCTTGG GCTCTGTCTCGTGTTTCTCATTGTGATGTTCTGCAGAAGGAAGACAACAAAGCTGTCAGTGCACATGGGC TGTGAAAATCCTATCAAGAGGCAGGAAGCGATCACATCCTATAATCACTGCCTATCTCCAACTGCATCTG ATGCTGTGACTCCAGGATGTTCCATACACAGGCTCATCAGCAGGACTCCAAGGTGCACAGCAATCCTGAG AATCCAAGACCCTTACAGAAGGACTCACCTCAGGAACAGAGCAGTGTCCACACTAAGATTTCCTTGGATT TCATGGGAGGGAAGCCTCAGGAGTACTCAGAGATCTAAATGCACCAAGCTTTGCTCTCCTGTGAAGAACC TGTGTCCTCTATGGCTTCCTGTGGATAATTCCTGCATCCCTCTGATCCCAGAGTGGGTTATGCTGCTGTG TGTGAGTCTTACACTCAGTTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001111058 |
| Insert Size | 1212 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001111058.1, NP_001104528.1 |
| RefSeq Size | 2571 bp |
| RefSeq ORF | 1212 bp |
| Locus ID | 12489 |
| UniProt ID | Q63994 |
| Gene Summary | Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state (By similarity). Preferentially binds sialic acid to the short O-linked glycans of certain mucins (PubMed:12773563).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Gene therapy for Alzheimer\'s Disease targeting CD33 reduces amyloid beta accumulation and neuroinflammation
,Griciuc, A;Federico, AN;Natasan, J;Forte, AM;McGinty, D;Nguyen, H;Volak, A;LeRoy, S;Gandhi, S;Lerner, EP;Hudry, E;Tanzi, RE;Maguire, CA;,
Hum. Mol. Genet.
,PubMed ID 32803224
[CD33]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG219965 | Cd33 (tGFP-tagged) - Mouse CD33 antigen (Cd33) transcript variant 1, (10ug) |
CNY 7,088.00 |
|
| MR219965 | Cd33 (Myc-DDK-tagged) - Mouse CD33 antigen (Cd33), transcript variant 1 |
CNY 5,488.00 |
|
| MR219965L3 | Lenti ORF clone of Cd33 (Myc-DDK-tagged) - Mouse CD33 antigen (Cd33), transcript variant 1 |
CNY 5,890.00 |
|
| MR219965L4 | Lenti ORF clone of Cd33 (mGFP-tagged) - Mouse CD33 antigen (Cd33), transcript variant 1 |
CNY 5,890.00 |
