Derl3 (NM_024440) Mouse Untagged Clone
CAT#: MC211061
Derl3 (untagged) - Mouse Der1-like domain family, member 3 (Derl3), (10ug)
CNY 3,990.00
Product images
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | 1810006I20Rik; 1810063P04Rik; derlin-3; IZP6 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC211061 representing NM_024440
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCTGGGCAGAGGCTGGCGGCGGGCTTCCTGCAGGTGCCCGCGGTGACACGCGCCTACACCGCGGCCT GCGTCCTCACCACGGCCGCAGTGCAGCTGGAGCTCCTCAGCCCCTTCCAGCTCTACTTCAACCCGCACCT GGTGTTCCGGAAGTTCCAGGTCTGGAGGCTCATCACCACCTTCCTCTTCTTCGGGCCCCTGGGATTCGGC TTCTTTTTCAACATGCTCTTCGTGTTCCGCTACTGCCGCATGCTGGAGGAGGGTTCTTTCCGTGGCCGCA AGGCTGACTTCGTTTTCATGTTTCTCTTCGGTGGTGTTCTTATGACTCTGCTGGGATTCCTGGGCAGCCT GTTTTTCCTGGGACAGGCCCTCATGGCCATGCTGGTCTATGTATGGAGCCGTCGCAGCCCTCACGTGAGG GTCAACTTCTTCGGCTTACTCAACTTCCAGGCACCATTCCTGCCCTGGGCCCTCATGGGCTTCTCGCTGC TGCTGGGCAACTCGGTTGTCACAGACCTGTTAGGGATCCTTGTGGGCCACATCTACTACTTCCTAGAAGA CGTCTTTCCCAACCAGCCCGGAGGCAAGAGACTGCTGCTGACCCCCAGCGTGTTGAAGCTGCTACTAGAT GACCCTCAGGAAGACCCCGATTACCTGCCCCTTCCCGAAGAGCAGCCAGAGCTCTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_024440 |
Insert Size | 687 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_024440.2, NP_077760.1 |
RefSeq Size | 1336 bp |
RefSeq ORF | 687 bp |
Locus ID | 70377 |
UniProt ID | Q9D8K3 |
Gene Summary | Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the misfolded glycoproteins. May be involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for proteasomal degradation.[UniProtKB/Swiss-Prot Function] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG222306 | Derl3 (tGFP-tagged) - Mouse Der1-like domain family member 3 (Derl3), (10ug) |
CNY 2,850.00 |
|
MR222306 | Derl3 (Myc-DDK-tagged) - Mouse Der1-like domain family, member 3 (Derl3) |
CNY 2,400.00 |
|
MR222306L3 | Lenti ORF clone of Derl3 (Myc-DDK-tagged) - Mouse Der1-like domain family, member 3 (Derl3) |
CNY 4,750.00 |
|
MR222306L4 | Lenti ORF clone of Derl3 (mGFP-tagged) - Mouse Der1-like domain family, member 3 (Derl3) |
CNY 4,750.00 |