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Fbxl21 (NM_178674) Mouse Untagged Clone
CAT＃: MC215746
Fbxl21 (untagged) - Mouse F-box and leucine-rich repeat protein 21 (Fbxl21), (10ug)
CNY 5,610.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | D630045D17Rik; FBL3B; FBXL3B; Psttm |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC215746 representing NM_178674
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAAGAGGAATAATTTCTCTGCCGTGAATAAGGTTGTCCAGTCGTCACCAGTAGTGAAACAGCCCAAAC GTGGGCTCTGCTCTTCCCTCCGCCAGACCCATGCGCTCTCTGTCCTTCTGGACTGGGGGACTTTACCTCA CCATGTCATATTACAGATCTTTCAGTACCTTCCTTTAATAGATCGAGCCCGGGCTTCGTCCGTGTGCAGG AGATGGAATGAAGTATTCCACATCCCTGATCTTTGGAGGAAGTTTGAGTTTGAGCTGAACCAATCAGCAA CTTCTTATTTCAAGTCCACTCATCCCGACCTCATTCAACAGATCATCAAAAAGCACGCTGCACATCTTCA GTATGTCAGCTTTAAGGTTGATAGCAGTACTGAGTCGGCAGAAGCCGCCTGTGATATCCTTTCTCAGCTG GTAAATTGTTCTATCCAGACCTTGGGATTGATTTCAACAGCCAAACCAAGTTTCATGAATGTGCCCAAGT CTCACTTTGTGTCGGCACTTACGGTCGTGTTTGTCAACTCAAAATCGTTATCATCGATTAAAATTGAGGA CACGCCAGTGGATGACCCTTCCCTGAAGATTCTTGTGGCTAACAACAGTGACACCCTTCGACTCCTCAAA ATGAGTAGCTGTCCTCACGTTTCATCTGATGGGATCCTCTGTGTGGCGGACCACTGTCAGGGCCTCCGAG AGCTGGCCCTGAATTACTACATTCTGAGCGACGAAATTCTCCTTGCGCTCTCCAGCGAGACTCACGTGAA CCTCGAACATCTCCGGATAGACGTTGTGAGTGAAAACCCGGGGCAGATCAAGTTCCATTCTATTAAGAAA CGCAGCTGGGACGCACTGATCAAACACTCCCCGAGAGTGAACGTCGTCATGTACTTCTTCTTGTATGAAG AAGAGTTTGAGGCATTCTTCAAAGAGGAAACCCCCGTCACTCACCTTTATTTCGGACGTTCAGTAAGCAG AGCCATCCTGGGCCGGATAGGTCTTAACTGCCCGAGGCTGATCGAGTTAGTGGTGTGTGCCAATGGCCTT CTGCCCCTGGACAGTGAACTCATCCGTATTGCCAAGCATTGTAAAAATCTAACCTCCTTGGGCCTGAGTG AGTGTGAAGTCAGCTGCAGCGCATTTGTAGAGTTTGTGAGACTCTGTGGCAGAAGGCTCACCCAGCTGTC TATCATGGAGGAAGTTCTGGTCCCTGACGACAGGTACACCCCAGATGAAGTCCACACTGAAGTCTCTAAG CACCTGGGAAGAGTGTGGTTTCCGGATGTGATGCCCATCTGGTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_178674 |
| Insert Size | 1305 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_178674.4, NP_848789.2 |
| RefSeq Size | 1965 bp |
| RefSeq ORF | 1305 bp |
| Locus ID | 213311 |
| UniProt ID | Q8BFZ4 |
| Gene Summary | Substrate-recognition component of the SCF(FBXL21) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF(FBXL21) complex mainly acts in the cytosol and mediates ubiquitination of CRY proteins (CRY1 and CRY2), leading to CRY proteins stabilization. The SCF(FBXL21) complex counteracts the activity of the SCF(FBXL3) complex and protects CRY proteins from degradation. Involved in the hypothalamic suprachiasmatic nucleus (SCN) clock regulating temporal organization of the daily activities.[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG220041 | Fbxl21 (tGFP-tagged) - Mouse F-box and leucine-rich repeat protein 21 (Fbxl21), (10ug) |
CNY 4,090.00 |
|
| MR220041 | Fbxl21 (Myc-DDK-tagged) - Mouse F-box and leucine-rich repeat protein 21 (Fbxl21) |
CNY 3,656.00 |
|
| MR220041L3 | Lenti ORF clone of Fbxl21 (Myc-DDK-tagged) - Mouse F-box and leucine-rich repeat protein 21 (Fbxl21) |
CNY 5,610.00 |
|
| MR220041L4 | Lenti ORF clone of Fbxl21 (mGFP-tagged) - Mouse F-box and leucine-rich repeat protein 21 (Fbxl21) |
CNY 5,610.00 |
