United States
Germany
Japan
United Kingdom
China
Nr1h3 (NM_001177730) Mouse Untagged Clone
CAT＃: MC215976
Nr1h3 (untagged) - Mouse nuclear receptor subfamily 1, group H, member 3 (Nr1h3), transcript variant 2, (10ug)
CNY 5,800.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AU018371; LXR; RLD1; Unr1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC215976 representing NM_001177730
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCCTTGTGGCTGGAGGCCTCAATGCCTGATGTTTCTCCTGATTCTGCAACGGAGTTGTGGAAGACAG AACCTCAAGATGCAGGAGACCAGGGAGGCAACACTTGCATCCTCAGGGAGGAAGCCAGGATGCCCCAGTC AACTGGGGTTGCTTTAGGGATAGGGTTGGAGTCAGCAGAGCCTACAGCCCTGCTCCCCAGGGCAGAGACC CTCCCAGAGCCGACAGAGCTTCGTCCACAAAAGCGGAAAAAGGGCCCAGCCCCCAAAATGCTGGGGAACG AGCTGTGCAGTGTCTGTGGGGACAAAGCCTCTGGCTTCCATTACAACGTGCTGAGCTGCGAGGGCTGCAA GGGATTCTTCCGCCGCAGTGTCATCAAGGGAGCACGCTATGTCTGCCACAGCGGTGGCCACTGCCCCATG GACACCTACATGCGGCGGAAATGCCAGGAGTGTCGACTTCGCAAATGCCGCCAGGCAGGCATGAGGGAGG AGTGTGTGCTGTCAGAAGAACAGATCCGCTTGAAGAAACTGAAGCGGCAAGAAGAGGAACAGGCTCAAGC CACTTCGGTGTCCCCAAGGGTGTCCTCACCTCCTCAAGTCCTGCCACAGCTCAGCCCAGAGCAGCTGGGC ATGATCGAGAAGCTGGTGGCTGCCCAGCAACAGTGTAACAGGCGCTCCTTCTCAGACCGCCTGCGCGTCA CGCCTTGGCCCATTGCACCCGACCCTCAGAGCCGGGAAGCCCGACAACAGCGCTTTGCCCACTTTACTGA GCTGGCCATCGTGTCCGTGCAGGAGATTGTTGACTTTGCCAAACAGCTCCCTGGCTTCCTACAGCTCAGC AGGGAGGACCAGATCGCCTTGCTGAAGACCTCTGCAATCGAGGTCATGCTTCTGGAGACGTCACGGAGGT ACAACCCCGGCAGTGAGAGCATCACCTTCCTCAAGGACTTCAGTTACAACCGGGAAGACTTTGCCAAAGC AGGGCTGCAGGTGGAGTTCATCAACCCCATCTTTGAGTTCTCCAGAGCCATGAATGAGCTGCAACTCAAT GATGCTGAGTTTGCTCTGCTCATTGCCATCAGCATCTTCTCTGCAGACCGGCCCAACGTGCAGGACCAGC TCCAAGTAGAGAGGCTGCAACACACATATGTGGAGGCCCTGCACGCCTACGTCTCCATCAACCACCCCCA CGACCCACTGATGTTCCCACGGATGCTAATGAAGCTGGTGAGCCTCCGTACTTTGAGCAGCGTCCATTCA GAGCAAGTGTTTGCCCTTCGCCTGCAGGACAAAAAGCTTCCCCCTCTGCTGTCTGAGATCTGGGATGTCC ACGAGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001177730 |
| Insert Size | 1338 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001177730.1, NP_001171201.1 |
| RefSeq Size | 1802 bp |
| RefSeq ORF | 1338 bp |
| Locus ID | 22259 |
| UniProt ID | Q9Z0Y9 |
| Gene Summary | Nuclear receptor that exhibits a ligand-dependent transcriptional activation activity (PubMed:18055760, PubMed:19520913, PubMed:20427281). Interaction with retinoic acid receptor (RXR) shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) contains a different segment for its 5' UTR, compared to variant 1. Variants 1, 2, and 3 all encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG227526 | Nr1h3 (tGFP-tagged) - Mouse nuclear receptor subfamily 1 group H member 3 (Nr1h3) transcript variant 2, (10ug) |
CNY 3,710.00 |
|
| MR227526 | Nr1h3 (Myc-DDK-tagged) - Mouse nuclear receptor subfamily 1, group H, member 3 (Nr1h3), transcript variant 2 |
CNY 3,656.00 |
|
| MR227526L3 | Lenti ORF clone of Nr1h3 (Myc-DDK-tagged) - Mouse nuclear receptor subfamily 1, group H, member 3 (Nr1h3), transcript variant 2 |
CNY 5,230.00 |
|
| MR227526L4 | Lenti ORF clone of Nr1h3 (mGFP-tagged) - Mouse nuclear receptor subfamily 1, group H, member 3 (Nr1h3), transcript variant 2 |
CNY 5,230.00 |
