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Cadm1 (NM_018770) Mouse Untagged Clone
CAT＃: MC215987
Cadm1 (untagged) - Mouse cell adhesion molecule 1 (Cadm1), transcript variant 3, (10ug)
CNY 5,800.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2900073G06Rik; 3100001I08Rik; AI987920; Bl2; Igsf4; Igsf4a; Necl2; RA175; RA175A; RA175B; RA175C |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC215987 representing NM_018770
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGAGTGCTGTGCTGCCGAGCGGATCCCAGTGTGCGGCGGCAGCGGCTGTGGCGGCGGCGGCGGCGC CTCCAGGGCTCCGGCTCCGGCTCCTGCTGTTGCTCCTTTCGGCCGCGGCACTGATCCCCACAGGTGATGG ACAGAATCTGTTTACTAAAGACGTGACAGTGATTGAAGGAGAAGTGGCAACCATCAGCTGCCAGGTCAAT AAGAGTGACGACTCAGTGATCCAGCTCCTGAACCCCAACAGGCAGACCATTTACTTCAGGGACTTCAGGC CTTTGAAGGACAGCAGGTTTCAGCTGCTGAATTTTTCTAGCAGTGAACTCAAAGTGTCACTGACGAATGT CTCAATCTCGGATGAAGGGAGATACTTCTGCCAGCTCTACACGGACCCCCCACAGGAGAGTTACACCACC ATCACAGTCCTGGTTCCTCCACGTAACTTGATGATCGATATCCAGAAAGACACGGCAGTTGAAGGGGAGG AGATTGAAGTCAACTGTACTGCCATGGCCAGCAAGCCAGCGACGACCATCAGGTGGTTCAAAGGGAACAA GGAACTCAAAGGCAAATCAGAGGTGGAGGAGTGGTCGGACATGTACACTGTGACCAGTCAGCTGATGCTG AAGGTGCACAAGGAGGACGACGGGGTCCCGGTGATCTGCCAGGTGGAGCACCCTGCGGTCACTGGAAACC TGCAGACCCAGCGCTATCTAGAAGTGCAGTATAAACCGCAAGTGCATATCCAGATGACTTACCCTCTGCA AGGCCTAACCCGGGAAGGGGATGCATTTGAGTTAACGTGTGAAGCCATCGGGAAGCCCCAGCCTGTGATG GTAACTTGGGTGAGAGTCGATGATGAAATGCCTCAACATGCCGTACTGTCTGGGCCAAACCTGTTCATCA ATAACCTAAACAAAACAGATAACGGTACTTACCGCTGTGAGGCTTCCAACATAGTGGGAAAGGCTCATTC GGACTATATGCTGTATGTATACGATCCCCCCACAACTATCCCTCCTCCCACAACAACCACCACCACTACC ACCACCACCACCACCACCATCCTTACCATCATCACAGATTCTCGAGCAGGTGAAGAGGGGACCATTGGGG CAGTGGACCACGCAGTGATTGGTGGCGTCGTAGCCGTGGTGGTGTTTGCCATGCTATGCTTGCTCATCAT TCTGGGCCGCTATTTTGCCAGACATAAAGGTACATACTTCACTCATGAAGCCAAAGGAGCCGATGACGCA GCAGACGCAGACACAGCTATAATCAATGCAGAAGGAGGACAGAACAACTCCGAAGAAAAGAAAGAGTACT TCATCTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_018770 |
| Insert Size | 1338 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_018770.3, NP_061240.3 |
| RefSeq Size | 4354 bp |
| RefSeq ORF | 1338 bp |
| Locus ID | 54725 |
| UniProt ID | Q8R5M8 |
| Gene Summary | Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and NECTIN3 in a Ca(2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly. May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (3) lacks an in-frame exon compared to variant 1. The resulting isoform (c) has the same N- and C-termini but is shorter compared to isoform a. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG222734 | Cadm1 (tGFP-tagged) - Mouse cell adhesion molecule 1 (Cadm1) transcript variant 3, (10ug) |
CNY 4,940.00 |
|
| MR222734 | Cadm1 (Myc-DDK-tagged) - Mouse cell adhesion molecule 1 (Cadm1), transcript variant 3 |
CNY 4,470.00 |
|
| MR222734L3 | Lenti ORF clone of Cadm1 (Myc-DDK-tagged) - Mouse cell adhesion molecule 1 (Cadm1), transcript variant 3 |
CNY 6,370.00 |
|
| MR222734L4 | Lenti ORF clone of Cadm1 (mGFP-tagged) - Mouse cell adhesion molecule 1 (Cadm1), transcript variant 3 |
CNY 6,370.00 |
