United States
Germany
Japan
United Kingdom
China
Rxra (NM_011305) Mouse Untagged Clone
CAT＃: MC216284
Rxra (untagged) - Mouse retinoid X receptor alpha (Rxra), (10ug)
CNY 3,656.00
CNY 6,080.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 9530071D11Rik; Nr2b1; RXRalpha1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>NCBI ORF sequence for NM_011305, the custom clone sequence may differ by one or more nucleotides
ATGGACACCAAACATTTCCTGCCGCTCGACTTCTCTACCCAGGTGAACTCTTCGTCCCTCAACTCTCCAA CGGGTCGAGGCTCCATGGCTGTCCCCTCGCTGCACCCCTCCTTGGGTCCGGGAATCGGCTCTCCACTGGG CTCGCCTGGGCAGCTGCACTCTCCTATCAGCACCCTGAGCTCCCCCATCAATGGCATGGGTCCGCCCTTC TCTGTCATCAGCTCCCCCATGGGCCCGCACTCCATGTCGGTACCCACCACACCCACATTGGGCTTCGGGA CTGGTAGCCCCCAGCTCAATTCACCCATGAACCCTGTGAGCAGCACTGAGGATATCAAGCCGCCACTAGG CCTCAATGGCGTCCTCAAGGTTCCTGCCCATCCCTCAGGAAATATGGCCTCCTTCACCAAGCACATCTGT GCTATCTGTGGGGACCGCTCCTCAGGCAAACACTATGGGGTATACAGTTGTGAGGGCTGCAAGGGCTTCT TCAAGAGGACAGTACGCAAAGACCTGACCTACACCTGCCGAGACAACAAGGACTGCCTGATCGACAAGAG ACAGCGGAACCGGTGTCAGTACTGCCGCTACCAGAAGTGCCTGGCCATGGGCATGAAGCGGGAAGCTGTG CAGGAGGAGCGGCAGCGGGGCAAGGACCGGAATGAGAACGAGGTGGAGTCCACCAGCAGTGCCAACGAGG ACATGCCTGTAGAGAAGATTCTGGAAGCCGAGCTTGCTGTCGAGCCCAAGACTGAGACATACGTGGAGGC AAACATGGGGCTGAACCCCAGCTCACCAAATGACCCTGTTACCAACATCTGTCAAGCAGCAGACAAGCAG CTCTTCACTCTTGTGGAGTGGGCCAAGAGGATCCCACACTTTTCTGAGCTGCCCCTAGACGACCAGGTCA TCCTGCTACGGGCAGGCTGGAACGAGCTGCTGATCGCCTCCTTCTCCCACCGCTCCATAGCTGTGAAAGA TGGGATTCTCCTGGCCACCGGCCTGCACGTACACCGGAACAGCGCTCACAGTGCTGGGGTGGGCGCCATC TTTGACAGGGTGCTAACAGAGCTGGTGTCTAAGATGCGTGACATGCAGATGGACAAGACGGAGCTGGGCT GCCTGCGAGCCATTGTCCTGTTCAACCCTGACTCTAAGGGGCTCTCAAACCCTGCTGAGGTGGAGGCGTT GAGGGAGAAGGTGTATGCGTCACTAGAAGCGTACTGCAAACACAAGTACCCTGAGCAGCCGGGCAGGTTT GCCAAGCTGCTGCTCCGCCTGCCTGCACTGCGTTCCATCGGGCTCAAGTGCCTGGAGCACCTGTTCTTCT TCAAGCTCATCGGGGACACGCCCATCGACACCTTCCTCATGGAGATGCTGGAGGCACCACATCAAGCCAC CTAG |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_011305 |
| Insert Size | 1404 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC138800, AAI38801 |
| RefSeq Size | 3216 bp |
| RefSeq ORF | 1404 bp |
| Locus ID | 20181 |
| UniProt ID | P28700 |
| Gene Summary | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. RXRA serves as a common heterodimeric partner for a number of nuclear receptors. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. The RXRA/PPARA heterodimer is required for PPARA transcriptional activity on fatty acid oxidation genes such as ACOX1 and the P450 system genes.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Thyroid Hormone Response Element Half-Site Organization and Its Effect on Thyroid Hormone Mediated Transcription
,null,
PLoS ONE
,PubMed ID 24971931
[Rxra]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG225069 | Rxra (tGFP-tagged) - Mouse retinoid X receptor alpha (Rxra), (10ug) |
CNY 3,710.00 |
|
| MR225069 | Rxra (Myc-DDK-tagged) - Mouse retinoid X receptor alpha (Rxra) |
CNY 3,656.00 |
|
| MR225069L3 | Lenti ORF clone of Rxra (Myc-DDK-tagged) - Mouse retinoid X receptor alpha (Rxra) |
CNY 5,230.00 |
|
| MR225069L4 | Lenti ORF clone of Rxra (mGFP-tagged) - Mouse retinoid X receptor alpha (Rxra) |
CNY 6,056.00 |
