Lrp4 (NM_001145857) Mouse Untagged Clone

CAT#: MC217359

Lrp4 (untagged) - Mouse low density lipoprotein receptor-related protein 4 (Lrp4), transcript variant 2, (10ug)



  "NM_001145857" in other vectors (2)

CNY 3,872.00

CNY 6,650.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (3)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Synonyms 6430526J12Rik; D230026E03; mdig; Megf7
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MC217359 representing NM_001145857
Red=Cloning site Blue=ORF

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGAGGCGGTGGTGGGGCGCGCTGCTGCTTGGCGCCCTGCTCTGCGCACACGGAATAGCCAGCAGTCTGG
AGTGTGCATGTGGTCGGAGCCACTTCACATGTGCGGTGAGCGCGCTTGGCGAATGTACCTGTATCCCCGC
CCAGTGGCAGTGTGATGGAGACAATGACTGTGGAGACCACAGCGATGAGGATGGCTGTACGCTGCCTACC
TGCTCCCCTCTGGACTTCCACTGTGACAACGGCAAGTGCATCCGACGCTCCTGGGTGTGTGACGGGGACA
ATGACTGTGAAGATGACTCTGATGAGCAGGACTGTCCCCCCCGGGAGTGTGAGGAGGACGAATTCCCCTG
CCAGAACGGCTACTGCATTCGGAGTCTGTGGCACTGTGATGGGGACAACGACTGTGGTGACAACAGTGAC
GAGCAATGCGACATGCGCAAGTGCTCAGACAAGGAATTCCGCTGCAGCGACGGCAGCTGCATTGCTGAGC
ATTGGTACTGCGATGGTGACACAGACTGCAAAGATGGCTCTGATGAGGAAAGCTGCCCTTCAGCAGTACC
CTCTCCTCCTTGCAACCTGGAAGAGTTCCAGTGCGCCTATGGCCGCTGCATCCTCGACATCTACCACTGT
GACGGAGATGACGACTGTGGAGACTGGTCAGACGAGTCTGACTGCTCCTCCCACCAGCCCTGCCGCTCTG
GGGAATTCATGTGTGACAGTGGCCTGTGCATCAACTCGGGCTGGCGCTGTGATGGTGATGCAGACTGTGA
TGACCAGTCTGATGAACGCAACTGCACCACCTCCATGTGCACAGCCGAACAGTTTCGCTGTCGGTCAGGC
CGTTGCGTCCGTCTGTCCTGGCGCTGTGATGGGGAGGATGACTGTGCGGACAACAGCGATGAAGAAAACT
GTGAGAACACAGGAAGCCCCCAGTGCGCCTCTGACCAGTTCCTGTGTTGGAACGGGCGCTGTATTGGGCA
GAGGAAGCTGTGCAACGGGATCAACGACTGCGGTGACAGCAGTGACGAAAGTCCACAGCAGAACTGTCGG
CCCCGGACGGGTGAGGAGAACTGCAATGTTAACAACGGTGGCTGTGCCCAGAAGTGTCAGATGGTGCGAG
GGGCAGTGCAGTGTACCTGCCACACAGGCTACCGGCTCACAGAGGATGGGAGAACGTGCCAGGATGTAAA
CGAATGTGCTGAGGAGGGGTACTGCAGCCAGGGCTGCACAAACACTGAAGGGGCTTTCCAGTGCTGGTGT
GAAGCAGGGTATGAGCTACGGCCCGATCGGCGCAGCTGCAAAGCTCTGGGGCCAGAACCTGTGCTACTGT
TTGCCAATCGTATCGACATCCGGCAGGTGCTCCCGCACCGCTCCGAGTACACGCTGCTACTGAACAACCT
GGAGAACGCCATTGCCCTCGACTTTCATCACCGGCGGGAGCTGGTCTTCTGGTCGGATGTCACCCTGGAC
CGCATCCTCCGTGCCAACCTTAATGGCAGCAATGTAGAGGAGGTGGTGTCTACTGGGCTAGAGAGCCCAG
GTAGGAAAACAAGGCCCTGA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Chromatograms CHROMATOGRAMS
Sequencher program is needed, download here.
Restriction Sites SgfI-MluI     
ACCN NM_001145857
Insert Size 1560 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_001145857.1, NP_001139329.1
RefSeq Size 3246 bp
RefSeq ORF 1560 bp
Locus ID 228357
UniProt ID Q8VI56
Gene Summary Mediates SOST-dependent inhibition of bone formation. Functions as a specific facilitator of SOST-mediated inhibition of Wnt signaling. Plays a key role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between motor neuron and skeletal muscle. Directly binds AGRIN and recruits it to the MUSK signaling complex. Mediates the AGRIN-induced phosphorylation of MUSK, the kinase of the complex. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the transcription of specific genes and the clustering of AChR in the postsynaptic membrane. Alternatively, may be involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway. More generally, has been proposed to function as a cell surface endocytic receptor binding and internalizing extracellular ligands for degradation by lysosomes. Plays an essential role in the process of digit differentiation (PubMed:16517118).[UniProtKB/Swiss-Prot Function]
Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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