United States
Germany
Japan
United Kingdom
China
Hpse (NM_152803) Mouse Untagged Clone
CAT＃: MC217567
Hpse (untagged) - Mouse heparanase (Hpse), (10ug)
CNY 5,984.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | H; Hpa; Hpr1; HSE1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>NCBI ORF sequence for NM_152803, the custom clone sequence may differ by one or more nucleotides
ATGCTGAGGCTGCTGCTGCTGTGGCTCTGGGGGCCGCTCGGTGCCCTGGCCCAGGGCGCCCCCGCGGGGA CCGCGCCGACCGACGACGTGGTAGACTTGGAGTTTTACACCAAGCGGCCGCTCCGAAGCGTGAGTCCCTC GTTCCTGTCCATCACCATCGACGCCAGCCTGGCCACCGACCCGCGCTTCCTCACCTTCCTGGGCTCTCCA AGGCTCCGTGCTCTGGCTAGAGGCTTATCTCCTGCATACTTGAGATTTGGCGGCACAAAGACTGACTTCC TTATTTTTGATCCGGACAAGGAACCGACTTCCGAAGAAAGAAGTTACTGGAAATCTCAAGTCAACCATGA TATTTGCAGGTCTGAGCCGGTCTCTGCTGCGGTGTTGAGGAAACTCCAGGTGGAATGGCCCTTCCAGGAG CTGTTGCTGCTCCGAGAGCAGTACCAAAAGGAGTTCAAGAACAGCACCTACTCAAGAAGCTCAGTGGACA TGCTCTACAGTTTTGCCAAGTGCTCGGGGTTAGACCTGATCTTTGGTCTAAATGCGTTACTACGAACCCC AGACTTACGGTGGAACAGCTCCAACGCCCAGCTTCTCCTTGACTACTGCTCTTCCAAGGGTTATAACATC TCCTGGGAACTGGGCAATGAGCCCAACAGTTTCTGGAAGAAAGCTCACATTCTCATCGATGGGTTGCAGT TAGGAGAAGACTTTGTGGAGTTGCATAAACTTCTACAAAGGTCAGCTTTCCAAAATGCAAAACTCTATGG TCCTGACATCGGTCAGCCTCGAGGGAAGACAGTTAAACTGCTGAGGAGTTTCCTGAAGGCTGGCGGAGAA GTGATCGACTCTCTTACATGGCATCACTATTACTTGAATGGACGCATCGCTACCAAAGAAGATTTTCTGA GCTCTGATGTGCTGGACACTTTTATTCTCTCTGTGCAAAAAATTCTGAAGGTCACTAAAGAGATCACACC TGGCAAGAAGGTCTGGTTGGGAGAGACGAGCTCAGCTTACGGTGGCGGTGCACCCTTGCTGTCCAACACC TTTGCAGCTGGCTTTATGTGGCTGGATAAATTGGGCCTGTCAGCCCAGATGGGCATAGAAGTCGTGATGA GGCAGGTGTTCTTCGGAGCAGGCAACTACCACTTAGTGGATGAAAACTTTGAGCCTTTACCTGATTACTG GCTCTCTCTTCTGTTCAAGAAACTGGTAGGTCCCAGGGTGTTACTGTCAAGAGTGAAAGGCCCAGACAGG AGCAAACTCCGAGTGTATCTCCACTGCACTAACGTCTATCACCCACGATATCAGGAAGGAGATCTAACTC TGTATGTCCTGAACCTCCATAATGTCACCAAGCACTTGAAGGTACCGCCTCCGTTGTTCAGGAAACCAGT GGATACGTACCTTCTGAAGCCTTCGGGGCCGGATGGATTACTTTCCAAATCTGTCCAACTGAACGGTCAA ATTCTGAAGATGGTGGATGAGCAGACCCTGCCAGCTTTGACAGAAAAACCTCTCCCCGCAGGAAGTGCAC TAAGCCTGCCTGCCTTTTCCTATGGTTTTTTTGTCATAAGAAATGCCAAAATCGCTGCTTGTATATGA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_152803 |
| Insert Size | 1608 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC138782, AAI38783 |
| RefSeq Size | 1791 bp |
| RefSeq ORF | 1608 bp |
| Locus ID | 15442 |
| UniProt ID | Q6YGZ1 |
| Gene Summary | This gene encodes an endoglucuronidase enzyme that plays an important role in tumor invasion and metastasis. The encoded preproprotein undergoes proteolytic processing to generate an active heterodimeric enzyme that cleaves the heparan sulfate proteoglycans associated with the cell surface and extracellular matrix. Mice lacking the encoded protein do not show any prominent pathological alterations under normal conditions but fail to develop albuminuria and renal damage in response to drug-induced diabetes. [provided by RefSeq, Aug 2016] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells
,Cheng, CC;Lee, YH;Lin, SP;Huangfu, WC;Liu, IH;,
J. Biomed. Sci.
,PubMed ID 24624965
[Hpse]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG221855 | Hpse (tGFP-tagged) - Mouse heparanase (Hpse), (10ug) |
CNY 5,890.00 |
|
| MR221855 | Hpse (Myc-DDK-tagged) - Mouse heparanase (Hpse) |
CNY 5,976.00 |
|
| MR221855L3 | Lenti ORF clone of Hpse (Myc-DDK-tagged) - Mouse heparanase (Hpse) |
CNY 7,220.00 |
|
| MR221855L4 | Lenti ORF clone of Hpse (mGFP-tagged) - Mouse heparanase (Hpse) |
CNY 7,220.00 |
