United States
Germany
Japan
United Kingdom
China
Cbfa2t3 (NM_009824) Mouse Untagged Clone
CAT＃: MC219793
Cbfa2t3 (untagged) - Mouse core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human) (Cbfa2t3), transcript variant 1, (10ug)
CNY 7,980.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | A630044F12Rik; AI465270; AW229127; Cbfa2t3h; ETO-2; Eto2; MTGR2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC219793 representing NM_009824
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCCCAGGCATCCACCACCACTCTGGAGAGTGGGGCACTCCTCTCGGGACCCCGGGGTCTTCAGAATG GAAGCCCAGCTCACAGGAAGGAGAAGGCTGCAGCAATGCCAGACTCCCCGGCTGAAGTGAAGACGCAGCC CCGGTCCACACCCCCCAGCATGCCGCCCCCACCTCCCACCTCATCCCAGGGAGCCACACGACCACCCTCC TTCACACCTCACACACATGGCGAGGATGGACCTGCGACGTCTCTTCCCCATGGCCGTTTCCACGGCTGCT TAAAGTGGTCCATGGTCTGTCTCTTGATGAACGGCAGCAGCCACTCACCCACGGCCATCCACGGTGCCCC ATCTACACCCAATGGCTTCAGCAACGGCCCAGCCACCTCATCCACGGCCTCGCTCTCCACACAGCACCTG CCCCCGGCGTGCGGGGCACGGCAGCTCAGCAAGCTTAAGCGTTTCCTCACCACCCTACAGCAGTTTGGCA GTGACATCTCACCTGAGATCGGGGAGCGCGTGCGCACACTGGTGCTGGGCCTGGTGAACTCAACTCTGAC GATCGAAGAGTTTCATGCCAAGCTCCAGGAAGCCACCAACTTTCCACTGAGGCCGTTTGTTATCCCTTTT CTGAAGGCTAATCTTCCACTGCTGCAGCGTGAGCTCCTGCACTGTGCCCGCCTGGCCAAACAGACACCTG CCCAGTACCTGGCCCAGCACGAACAGCTGCTGCTGGACGCCAGCGCCACCTCCCCTGTCGACTCGTCTGA GCTCCTGCTGGAAGTCAACGAGAACGGCAAAAGGAGAACACCTGACAGGACCAAAGAGAATGGATCAGAC CGGGACCCTCTGCACCCCGACCACCTCAGTAAGCGGTCCTGCACCCTGAGCCCCGCCCAGCGCTGCAGCC CCAGCAATGGGCTGCCCCACCCGACGCCACCCCCACCCCCGCACTATCGCCTGGAGGACATGGCCATGGC CCACCATTTCCGGGACTCCTACCGCCATCCTGATCCCCGAGAGCTACGGGAACGCCACCGGCCCCTGGCC ATACCTGGGTCTCGACAAGAAGAAGTGATTGATCACAGGCTCACAGAACGCGAGTGGGCAGAAGAATGGA AGCACCTCAACAGTCTTCTGAACTGCATCATGGACATGGTGGAGAAGACCCGGCGATCCCTCACCGTCCT GCGCCGGTGTCAGGAGGCCGACCGTGAGGAACTCAACCACTGGATCCGGTGCTACAGTGACTCTGAGGAG GGGAAGAAGGGCCCTACCCCCATCTCTGCCCGGTCCCTCAACAGCTGCAGTGGCCCTGAGGGGTCTCAGC TAGATGTTCACCGGGACTTCACGCCCAGGACCCTGTCTGGCTACATGCCTGAAGAGATCTGGAGGAAGGC TGAAGAAGCTGTGAATGAGGTGAAGCGCCAGGCCATGTCAGAACTACAGAAAGCTGTGTCTGATGCGGAG CGCAAAGCCCATGAACTCATCACCACAGAGCGTGCCAAGATGGAACGAGCCCTGGCGGAGGCCAAGCGAC AGGCCTCGGAGGATGCCCTGACTGTCATCAACCAGCAAGAGGACTCCAGCGAGAGCTGCTGGAACTGCGG GCGCAAGGCCAGCGAGACGTGCAGTGGCTGTAACGCCGCCCGCTACTGCGGGTCCTTCTGTCAGCACAAA GACTGGGAGAAACACCATCACGTGTGCGGCCAGAGTCTGCAGGGCCCCGCGGCTGCAGTGGCTGACCCAC TACCTGGACAGCCTGACGCCACTGCCAGCCCCAGCGAAGCCGGCTCGGCAGGGCCCTCTCGTCCCTGCTC TCCGGGGCCGCCAGGCCCGCTGGACGCTGCTGTGCCCCGCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_009824 |
| Insert Size | 1863 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_009824.2, NP_033954.2 |
| RefSeq Size | 7659 bp |
| RefSeq ORF | 1863 bp |
| Locus ID | 12398 |
| UniProt ID | O54972 |
| Gene Summary | Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes. Can repress the expression of MMP7 in a ZBTB33-dependent manner. Reduces the protein levels and stability of the transcriptinal regulator HIF1A; interacts with EGLN1 and promotes the HIF1A prolyl hydroxylation-dependent ubiquitination and proteasomal degradation pathway. Contributes to inhibition of glycolysis and stimulation of mitochondrial respiration by down-regulating the expression of glycolytic genes including PFKFB3, PFKFB4, PDK1, PFKP, LDHA and HK1 which are direct targets of HIF1A (By similarity). Regulates the proliferation and the differentiation of erythroid progenitors by repressing the expression of TAL1 target genes (PubMed:16407974). Plays a role in granulocyte differentiation (PubMed:15231665).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) encodes the longest protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG219692 | Cbfa2t3 (tGFP-tagged) - Mouse core-binding factor runt domain alpha subunit 2 translocated to 3 (human) (Cbfa2t3) transcript variant 1, (10ug) |
CNY 6,080.00 |
|
| MR219692 | Cbfa2t3 (Myc-DDK-tagged) - Mouse core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human) (Cbfa2t3), transcript variant 1 |
CNY 4,616.00 |
|
| MR219692L3 | Lenti ORF clone of Cbfa2t3 (Myc-DDK-tagged) - Mouse core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human) (Cbfa2t3), transcript variant 1 |
CNY 7,016.00 |
|
| MR219692L4 | Lenti ORF clone of Cbfa2t3 (mGFP-tagged) - Mouse core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human) (Cbfa2t3), transcript variant 1 |
CNY 7,410.00 |
其它Cbfa2t3产品
