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Epha7 (BC026153) Mouse Untagged Clone
CAT＃: MC220717
Epha7 (untagged) - Mouse Eph receptor A7 (cDNA clone MGC:14056 IMAGE:3991628), (10ug)
CNY 9,120.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | Ehk3, Mdk1, Cek11, Hek11 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC026153
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGTTGTTCAAACTCGGTTCCCTTCGTGGATTATTTTGTGTTACATCTGGCTGCTTGGCTTTGCACACA CGGGGGAGGCGCAGGCTGCGAAGGAAGTACTATTACTGGACTCGAAAGCACAACAAACAGAATTGGAATG GATTTCCTCTCCACCCAGTGGGTGGGAAGAAATTAGTGGTTTGGATGAGAACTACACTCCGATAAGAACA TACCAGGTGTGCCAGGTCATGGAGCCCAACCAGAACAACTGGCTGCGGACTAACTGGATTTCTAAAGGCA ACGCACAAAGGATTTTTGTAGAATTGAAATTCACCTTGAGGGATTGTAATAGTCTTCCCGGAGTCCTGGG AACTTGCAAGGAAACGTTTAATTTGTACTATTATGAAACAGACTACGACACCGGCAGGAATATACGAGAA AACCTTTATGTTAAAATAGACACCATTGCTGCAGATGAAAGTTTCACACAAGGTGACCTTGGTGAAAGAA AGATGAAGCTGAACACTGAGGTGAGAGAGATTGGACCTTTGTCCAAAAAGGGATTCTATCTTGCCTTTCA GGATGTAGGGGCTTGCATAGCATTGGTTTCTGTCAAAGTGTACTACAAGAAGTGCTGGTCCATTGTTGAG AACTTAGCTGTCTTTCCAGATACAGTGACTGGTTCGGAATTTTCGTCCTTAGTCGAGGTCCGTGGGACAT GTGTCAGCAGTGCCGAGGAAGAGGCAGAAAATTCCCCCAGGATGCATTGCAGTGCAGAAGGAGAGTGGCT AGTACCCATTGGAAAATGCATCTGCAAAGCAGGCTATCAGCAAAAAGGGGACACTTGCGAACCCTGTGGC CGCAGGTTCTACAAATCTTCCTCTCAGGATCTCCAGTGTTCTCGTTGTCCAACCCACAGCTTCTCTGACC GAGAAGGATCATCCAGGTGTGAATGTGAAGATGGGTACTACAGAGCTCCTTCTGATCCACCATACGTTGC ATGCACGAGGCCTCCCTCTGCACCACAGAACCTTATTTTCAACATCAATCAAACGACTGTAAGTTTGGAA TGGAGTCCTCCGGCTGACAACGGGGGAAGAAACGATGTCACCTACAGAATACTGTGTAAGCGGTGCAGTT GGGAACAGGGAGAATGTGTGCCATGCGGAAGTAACATTGGATACATGCCCCAGCAGACAGGATTAGAGGA TAACTATGTCACTGTCATGGACCTACTTGCCCATGCAAATTACACTTTCGAAGTTGAAGCTGTAAATGGA GTTTCGGACTTAAGCAGATCCCAGAGGCTCTTCGCTGCAGTTAGCATCACTACCGGTCAAGCAGCTCCCT CGCAAGTGAGTGGAGTCATGAAGGAGCGAGTACTGCAGCGGAGTGTGCAGCTTTCCTGGCAGGAGCCGGA GCATCCCAATGGAGTCATCACCGAATATGAAATCAAGTATTATGAGAAAGATCAACGGGAAAGGACGTAC TCAACACTCAAAACCAAGTCCACCTCCGCCTCCATTAATAATCTGAAACCGGGAACAGTGTATGTGTTTC AGATCCGGGCGGTCACTGCTGCCGGTTATGGAAACTACAGCCCTAGGCTTGATGTTGCCACACTTGAGGA AGCTTCAGGTAAAATGTTTGAAGCGACAGCAGTCTCCAGTGAACAGAATCCTGTCATCATAATTGCTGTA GTGGCTGTAGCAGGGACCATCATCTTGGTGTTCATGGTGTTCGGCTTCATCATTGGAAGAAGGCACTGTG GTTATAGCAAGGCTGACCAAGAAGGGGATGAAGAACTCTACTTTCATTGCACCAAAACCTACATTGACCC TGAAACCTATGAGGACCCAAATAGAGCTGTCCATCAATTCGCCAAGGAGCTAGATGCCTCCTGTATTAAA ATTGAGCGTGTGATTGGTGCAGGAGAATTTGGAGAAGTTTGCAGTGGTCGTTTGAAACTTCCGGGGAAGA GAGATGTTGCAGTGGCCATAAAAACCCTGAAAGTTGGTTACACAGAAAAACAAAGGAGGGACTTTTTATG CGAAGCAAGCATCATGGGGCAATTTGACCACCCAAATGTCGTCCATTTGGAAGGGGTTGTTACAAGAGGG AAGCCTGTCATGATTGTGATAGAGTTCATGGAGAATGGAGCCCTGGATGCATTTCTCAGGAAACACGATG GGCAGTTTACAGTCATTCAGTTGGTAGGAATGCTGAGAGGTATTGCCGCTGGGATGCGATACTTGGCTGA TATGGGATACGTTCACAGGGACCTTGCAGCACGCAACATCCTTGTCAACAGCAATCTTGTTTGTAAAGTG TCAGATTTTGGCCTTTCCCGGGTTATAGAGGATGATCCCGAAGCTGTCTACACCACGACTGGTGGAAAAA TTCCAGTAAGGTGGACTGCACCGGAAGCCATTCAATACCGGAAGTTCACCTCAGCCAGCGATGTGTGGAG CTATGGGATTGTCATGTGGGAAGTGATGTCTTATGGAGAAAGACCTTACTGGGACATGTCAAATCAAGAT GTCATTAAAGCGATAGAAGAAGGTTATCGTTTGCCGGCGCCCATGGATTGCCCAGCTGGTCTTCACCAGC TAATGCTGGATTGTTGGCAGAAAGATCGGGCGGAAAGGCCAAAGTTTGAGCAGATAGTCGGAATTCTAGA CAAAATGATTCGAAACCCAAGTAGTCTGAAAACACCCCTGGGAACTTGTAGTAGACCCATAAGCCCTCTT CTGGACCAGAGCACTCCTGACTTCACTGCCTTCTGTTCAGTTGGAGAATGGTTGCAAGCTATTAAAATGG AAAGGTATAAGGACAACTTCACAGCAGCGGGTTACAACTCACTCGAGTCAGTGGCCAGGATGACTATCGA TGATGTGATGAGTTTAGGGATCACACTGGTTGGCCATCAAAAGAAGATCATGAGCAGCATCCAGACTATG CGGGCACAAATGTTGCATTTACACGGAACAGGCATCCAAGTGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCTGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | BC026153 |
| Insert Size | 2985 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | BC026153, AAH26153 |
| RefSeq Size | 3554 bp |
| RefSeq ORF | 2984 bp |
| Locus ID | 13841 |
| Gene Summary | Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus. May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity. Forward signaling may result in activation of components of the ERK signaling pathway including MAP2K1, MAP2K2, MAPK1 AND MAPK3 which are phosphorylated upon activation of EPHA7. Isoform 4 which lacks the kinase domain may regulate isoform 1 adhesive properties.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG211406 | Epha7 (tGFP-tagged) - Mouse Eph receptor A7 (cDNA clone MGC:14056 IMAGE:3991628) |
CNY 10,830.00 |
|
| MR211406 | Epha7 (Myc-DDK-tagged) - Mouse Eph receptor A7 (cDNA clone MGC:14056 IMAGE:3991628) |
CNY 9,880.00 |
|
| MR211406L3 | Lenti ORF clone of Epha7 (Myc-DDK-tagged) - Mouse Eph receptor A7 (cDNA clone MGC:14056 IMAGE:3991628) |
CNY 11,780.00 |
|
| MR211406L4 | Lenti ORF clone of Epha7 (mGFP-tagged) - Mouse Eph receptor A7 (cDNA clone MGC:14056 IMAGE:3991628) |
CNY 11,780.00 |
