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Jup (NM_010593) Mouse Untagged Clone
CAT＃: MC221283
Jup (untagged) - Mouse junction plakoglobin (Jup), (10ug)
CNY 9,690.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | Ctnng; D930025P04Rik; PG |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC221283 representing NM_010593
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGGTGATGAACCTTATTGAGCAGCCCATCAAGGTGACAGAGTGGCAACAGACATACACCTACGACT CGGGCATCCACTCCGGCGTCAATACCTGTGTGCCCTCTGTAAGCAGCAAGGGCATCATGGATGAGGATGA TGCCTGCGGCAGACAGTACACACTCAAGAAGACTACCACCTATACACAAGGGGTGCCACAGAACCAAGGT GACCTGGAATACCAGATGTCCACAACGGCCAGAGCCAAGCGGGTGCGGGAGGCCATGTGTCCAGGGGTCT CAGGCGAGGACAGTTCTCTACTGCTGGCCACCCAGGTGGAGGGGCAGACAACCAATCTGCAGCGCCTGGC CGAACCATCCCAGTTGCTCAAGTCGGCCATCGTCCATCTCATCAACTACCAGGATGATGCAGAGCTGGCC ACCCGGGCTCTGCCTGAGCTCACCAAGCTGCTCAACGATGAGGACCCGGTAGTGGTGACCAAGGCGGCTA TGATCGTGAACCAGCTGTCCAAGAAGGAGGCATCCCGCCGGGCTCTAATGGGCTCGCCCCAGCTGGTGGC GGCGGTGGTGCGGACTATGCAGAACACCAGTGACCTGGATACTGCCCGGTGTACCACCAGCATCCTGCAC AACCTCTCTCACCACCGAGAGGGCTTGCTCGCCATATTCAAGTCTGGAGGCATCCCTGCCCTAGTCCGAA TGCTCAGTTCCCCCGTAGAATCTGTCCTGTTCTACGCCATCACCACACTGCACAACCTGCTGCTCTATCA GGAGGGCGCCAAGATGGCGGTGCGTCTGGCAGACGGGCTGCAGAAGATGGTGCCCCTACTCAACAAGAAC AACCCTAAGTTCCTGGCCATCACTACTGACTGCCTGCAGCTCCTGGCCTATGGCAACCAGGAGAGCAAGC TGATCATCCTGGCCAATGGGGGACCCCAAGGGCTTGTGCAGATCATGAGGAACTACAGCTACGAGAAGCT TCTGTGGACCACCAGCCGTGTGCTCAAGGTGCTCTCCGTGTGTCCTAGCAACAAGCCCGCCATCGTGGAG GCTGGTGGGATGCAGGCTCTGGGCAAGCACTTGACAAGCAACAGTCCCCGCCTGGTGCAGAACTGCCTGT GGACTCTGCGCAATCTCTCGGATGTAGCCACCAAGCAGGAGGGCCTGGAGAGTGTGCTGAAGATCCTGGT CAACCAACTGAGTGTAGATGACGTCAACGTCCTCACCTGTGCCACGGGCACCCTCTCCAACCTGACCTGC AACAACAGCAAAAACAAGACGCTGGTGACACAGAACAGTGGCGTGGAGGCGCTCATCCACGCCATCCTGA GAGCCGGAGACAAAGATGACATCACAGAGCCCGCTGTCTGTGCCCTGCGCCACCTTACCAGCCGTCACCC CGAGGCTGAGATGGCCCAGAACTCTGTGCGCCTCAACTATGGAATCCCGGCCATTGTGAAACTGCTCAAC CAGCCAAACCAGTGGCCACTGGTCAAGGCAACTATTGGCCTGATCCGGAACCTGGCTCTGTGCCCAGCCA ACCATGCCCCTCTGCAGGAGGCCGCGGTCATTCCCCGCCTCGTCCAGCTGTTGGTCAAGGCCCACCAGGA CGCCCAGCGCCATGTGGCTGCAGGCACCCAGCAGCCCTACACGGATGGTGTGAGGATGGAGGAGATCGTG GAAGGCTGCACCGGAGCCCTGCACATCCTCGCCCGGGATCCCATGAACCGCATGGAGATCTTCCGGCTCA ACACCATTCCCCTGTTTGTCCAGCTCCTGTACTCCTCTGTGGAGAACATCCAGCGTGTGGCTGCGGGAGT GCTCTGCGAGCTGGCCCAGGACAAGGAGGCTGCCGACGCCATTGATGCGGAGGGCGCCTCTGCCCCTCTC ATGGAGCTACTCCATTCCCGCAATGAGGGCACCGCGACCTACGCTGCTGCTGTCCTGTTCCGCATCTCTG AGGACAAGAACCCAGATTACCGTAAGCGAGTGTCTGTGGAGCTCACCAATTCCCTCTTCAAGCATGACCC AGCTGCCTGGGAGGCTGCCCAGAGTATGATCCCGATCAACGAACCCTATGCAGACGACATGGATGCCACC TACCGCCCCATGTACTCCAGCGATGTGCCTCTGGACCCTCTGGACATGCACATGGACCTGGATGGAGACT ACCCCATGGACACCTACAGTGACGGCCTGAGGCCTCCCTACCCCACTGCAGACCACATGCTGGCCTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_010593 |
| Insert Size | 2238 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_010593.2, NP_034723.1 |
| RefSeq Size | 5009 bp |
| RefSeq ORF | 2238 bp |
| Locus ID | 16480 |
| UniProt ID | Q02257 |
| Gene Summary | Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG210428 | Jup (tGFP-tagged) - Mouse junction plakoglobin (Jup) |
CNY 8,170.00 |
|
| MR210428 | Jup (Myc-DDK-tagged) - Mouse junction plakoglobin (Jup) |
CNY 7,410.00 |
|
| MR210428L3 | Lenti ORF clone of Jup (Myc-DDK-tagged) - Mouse junction plakoglobin (Jup) |
CNY 9,310.00 |
|
| MR210428L4 | Lenti ORF clone of Jup (mGFP-tagged) - Mouse junction plakoglobin (Jup) |
CNY 9,310.00 |
