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Usp16 (NM_024258) Mouse Untagged Clone
CAT＃: MC221839
Usp16 (untagged) - Mouse ubiquitin specific peptidase 16 (Usp16), (10ug)
CNY 10,550.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 1200004E02Rik; 2810483I07Rik; 6330514E22Rik; UBPM |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC221839 representing NM_024258
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGGAAGAAACGGACCAAGGGGAGAAGTGCTCCAGACACGGTGGCCTCAGAGTCTGCAGAACCAGTGT GCAGACACCTTAGAAAAGGGTTGGAACAAGGTAATTTGAAAAAAGCTTTAGTAAATGTGGAGTGGAATAT CTGCCAAGACTGTAAGACTGACAATAAAGTGAAAGATAAACCTGAGGAGGAAGCAGAAGACCCTTCGGTT TGGCTCTGTCTTAAATGTGGCCATCAGGGCTGTGGCAGAGATTCTCAGGAGCAGCATGCCTTGAAGCACT ACACGACACCGAGATCCGAGCCTCACTACCTGGTGCTCAGTCTGGACAACTGGAGCGTCTGGTGCTACAA GTGTGACGAGGAAGTCAAGTACTGTAGCTCAAACCGATTGGGCCAAGTGGTTGATTATGTTAGAAAACAA GCTGGCGTAAGAACTTCAAAACCAGCAGAGAAAAATAATGGACACATTGAGCTCGAAAATAAAAAATTGG AGAAAGAGAGTAAAAATGAACAAGAGAGAGAGAAATCGGAAAACCTGGCTAAAGAAACTATTCCCATGGA CTCTGCTTCCCAGATAACTGTGAAAGGACTCAGTAATTTGGGGAATACTTGTTTCTTCAATGCAGTTATG CAGAACTTGTCACAAACGCCAGTGCTTAGAGAACTACTAAAAGAAGTGAAGATGTCTGGAACGATTGTAA AAATAGAGCCACCTGATCTGGCACTAACAGAACCTTTAGAAGTAAACCTCGAGCCTCCAGGTCCTCTTAC TTTAGCCATGAGCCAGTTTCTCAGTGAGATGCAAGAGAACAAAAAGCGAGTTGTGACACCTAAAGAGCTC TTTTCTCAGGTCTGTAAAAAAGCAACACGTTTTAAAGGGTACCAGCAACAAGACAGCCAGGAGCTGCTTC GCTACCTACTGGATGGGATGAGAGCGGAAGAACACCAAAGAGTGAGTAAAGGAATTCTTAAAGCATTTGG TAATTCTACTGAAAAATTGGATGAAGAAGTAAAAAATAAAGTTAAAGATTATGAAAAGAAAAAGGCAATC CCGAGTTTTGTGGACCGCATCTTTGGTGGCGAGCTGACTAGTACGATCATGTGTGATGAATGCAGGACTG TCTCCTTAGTGCATGAATCGTTCCTTGATTTGTCTCTTCCAGTTTTAGATGATCAGAGTGGTAAGAAAAG TATAAATGATAAAAATGTGAAAATGACAATGGAGGAAGAAGATAAAGACAGTGAGGAAGAGAAAGATGAC AGCTACATGAAATCAAGGAGCGATCTTCCGTCAGGGACAAGCAAGCACCTACAGAAAAAGGCAAAGAAGC AGGCCAAAAAGCAGGCCAAGAACCAACGAAGGCAACAAAAAATTCAAGAAAGATTTCTTCACTTCAATGA GCTCTGCGCCACTGACTACACGGAAGACAATGAACGTGAAGCTGACACAGCACTTGCGGGAGAAGTGGAA GTGGATACCGACTCCACCCATGGTTCTCAAGAGGAGGCCACACAGATAGAGCTGTCTGTTAACCAGAAGG ATTTGGATGGCCAAGAGAGCATGATAGAAAGGACACCTGATGTGCAGGAAAGCCCAGAGGACCTAGGAGT GAAAAGTGCTAACACCGAGAGTGATCTGGGGATTGTGACGCCTGCTCCTGAATGTCCTAGGGATTTCAAT GGTGCCTTCCTGGAAGAAAGGACCAGTGGAGAACTAGACATTATCAATGGTTTAAAAAACCTTAATTTGA ATGCTGCTGTTGATCCTGATGAAATAAATATAGAGATTCCGAATGACAGTCATTCTGCACCCAAGGTATA TGAGGTCATGAACGAGGACCCAGAAACTGCTTTCTGTACCCTCGCGAACCGAGAAGCGTTTAGTACTGAT GAGTGTTCCATTCAACATTGCTTATATCAGTTCACCCGGAATGAGAAACTTCAAGATGCCAATAAACTGC TTTGTGAAGTGTGTTCAAGACGGCAGTGTAATGGACCAAAGGCAAATATAAAAGGTGACAGGAGACATGT TTACACCAATGCCAAGAAGCAGATGCTGGTCTCCCTCGCGCCTCCTGTCCTCACTCTGCATTTAAAGCGA TTCCAGCAGGCTGGTTTTAACCTGCGCAAAGTTAACAAACACATAAAGTTTCCAGAAATCTTAGATTTGG CTCCTTTTTGTACCCTTAAATGTAAGAATGTTGCTGAAGAAAGTACACGAGTGCTGTATTCCTTATATGG AGTTGTTGAACACAGTGGTACTATGAGGTCAGGGCATTACACTGCCTATGCGAAGGAGAGAACTGCAAGC TGTCACCTCTCCAATCTTGTTCTTCACGGTGACATTCCACAAGATTGTGAAATGGAATCAACCAAAGGGC AGTGGTTTCACATCAGCGATACACATGTGCAAGCTGTGCCTATAACTAAAGTACTGAACTCACAAGCGTA TCTCCTATTTTATGAGAGAATACTGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_024258 |
| Insert Size | 2478 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_024258.2, NP_077220.2 |
| RefSeq Size | 2926 bp |
| RefSeq ORF | 2478 bp |
| Locus ID | 74112 |
| UniProt ID | Q99LG0 |
| Gene Summary | Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes (PubMed:24034696). Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG210833 | Usp16 (tGFP-tagged) - Mouse ubiquitin specific peptidase 16 (Usp16) |
CNY 6,370.00 |
|
| MR210833 | Usp16 (Myc-DDK-tagged) - Mouse ubiquitin specific peptidase 16 (Usp16) |
CNY 6,048.00 |
|
| MR210833L3 | Lenti ORF clone of Usp16 (Myc-DDK-tagged) - Mouse ubiquitin specific peptidase 16 (Usp16) |
CNY 7,700.00 |
|
| MR210833L4 | Lenti ORF clone of Usp16 (mGFP-tagged) - Mouse ubiquitin specific peptidase 16 (Usp16) |
CNY 7,700.00 |
