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Srrt (NM_001109909) Mouse Untagged Clone
CAT＃: MC222279
Srrt (untagged) - Mouse serrate RNA effector molecule homolog (Arabidopsis) (Srrt), transcript variant 2, (10ug)
CNY 11,120.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2810019G02Rik; Ars2; Asr2; ASR2A; ASR2B; ASR2C; ASR2D |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC222279 representing NM_001109909
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGTGACAGTGATGATGAATACGACCGAAGACGCAGGGACAAATTTCGAAGAGAGCGCAGCGATTATG ACCGTTCCCGGGAAAGGGATGAAAGACGGCGAGGGGACGATTGGAATGACCGAGAGTGGGACCGTGGCCG GGAGCGCCGCAGTCGGGGTGAATATCGAGACTACGACAGGAACCGAAGGGAGCGCTTCTCTCCCCCTCGA CACGAACTAAGCCCCCCCCAGAAGCGCATGCGGAGAGACTGGGATGAGCACAGCTCTGACCCATACCACA GTGGCTATGACATGCCCTATGCTGGGGGGGGTGGGGGACCAACTTACGGCCCCCCTCAGCCCTGGGGCCA CCCAGACGTCCACATCATGCAGCACCATGTCCTGCCCATCCAGGCCAGGCTGGGCAGCATCGCAGAGATT GACTTGGGGGTGCCACCGCCCATAATGAAGTCCTTCAAAGAGTTCCTCCTGTCTCTGGATGACTCTGTGG ATGAGACAGAGGCAGTTAAACGCTACAATGACTACAAGCTGGACTTCCGAAGGCAGCAGATGCAGGACTT TTTCCTGGCTCACAAAGACGAGGAGTGGTTCCGATCTAAGTACCACCCTGATGAGGTGGGAAAGCGTCGG CAGGAGGCCCGGGGGGCCCTGCAGAACCGGCTGAAGGTGTTCCTGTCCCTCATGGAGAGTGGCTGGTTTG ATAACCTTCTCTTGGACATAGACAAAGCTGATGCCATTGTCAAGATGCTAGATGCAGCTGTCATTAAGAT GGAAGGTGGCACAGAGAACGATCTCCGAATTTTGGAGCAGGAGGAGGAGGAGGAACAGGCAGGCAAGACT GGGGAGGCCAGCAAGAAAGAGGAGGCCCGTGCTGGACCAGCCCTGGGAGAAGGAGAGCGCAAAGCCAATG ATAAGGATGAGAAGAAAGAAGATGGAAAACAGGCTGAGAATGACAGTTCCAACGATGACAAAACTAAAAA ATCTGAGGGTGATGGGGACAAGGAGGAGAAGAAAGAAGAGGCTGAGAAGGAAGCCAAAAAGAGCAAGAAG CGGAACAGGAAGCAGAGTGGCGATGACAGCTTCGATGAGGGCAGTGTGTCCGAGTCTGAGTCCGAGTCTG AGGGTGGCCAGGCCGAGGAGGAGAAGGAGGAGGCCGAAGAAGCACTTAAAGAAAAGGAGAAGCCCAAAGA GGAGGAGAAGGAGAAGCCTAAGGATGCTGCAGGGTTGGAGTGTAAGCCCCGGCCCTTGCATAAGACTTGC TCTCTCTTCATGCGCAACATCGCACCCAACATTTCAAGGGCAGAGATCATTTCTCTTTGTAAACGATACC CAGGCTTTATGCGAGTGGCACTGTCAGAGCCCCAGCCAGAGAGGAGGTTTTTTCGCCGTGGCTGGGTGAC TTTTGACCGCAGTGTTAACATTAAGGAGATCTGTTGGAACCTGCAGAACATTCGGCTCCGGGAGTGTGAA CTGAGTCCCGGTGTGAACAGAGACCTGACCCGTCGTGTCCGCAACATAAATGGCATTACACAGCACAAGC AGATAGTGCGCAATGACATCAAGTTGGCAGCCAAGCTAATCCACACACTGGATGACAGGACCCAGCTCTG GGCCTCTGAGCCTGGGACGCCTCCTGTGCCCACAAGCCTCCCCTCGCAAAACCCCATCCTGAAGAACATC ACTGACTACCTGATTGAGGAAGTGAGTGCGGAGGAGGAGGAGCTTCTGGGGAGCAGTGGGGGACCCCCTC CTGAGGAGCCTCCCAAGGAGGGCAACCCAGCCGAGATCAACGTGGAGAGAGATGAGAAGCTGATCAAGGT CTTGGATAAACTTCTTCTCTATTTGCGTATTGTGCATTCTCTGGATTATTATAACACCTGTGAGTACCCT AATGAAGACGAGATGCCCAACCGCTGTGGCATAATCCACGTTCGGGGGCCCATGCCTCCCAACCGAATTA GTCACGGAGAAGTGCTGGAGTGGCAGAAGACATTTGAGGAGAAACTGACTCCACTGTTGAGTGTGCGTGA ATCCCTTTCTGAGGAAGAGGCCCAGAAGATGGGTCGAAAAGACCCAGAGCAGGAAGTGGAGAAGTTTGTC ACCTCCAACACGCAGGAACTGGGCAAGGATAAGTGGCTATGTCCTCTCAGTGGCAAGAAATTCAAGGGCC CGGAGTTTGTGCGCAAGCATATCTTCAATAAGCATGCCGAGAAGATCGAGGAGGTGAAGAAGGAGGTGGC GTTCTTCAATAACTTTCTCACAGACGCCAAGCGCCCAGCTTTGCCTGAGATCAAGCCAGCTCAGCCACCT GGCCCTGCCCAGATACTCCCCCCAGGCCTGACCCCAGGACTTCCCTACCCACATCAGACGCCACAGGGCT TGATGCCATATGGTCAGCCCCGGCCTCCCATCTTGGGCTATGGAGTCCCAACAGGAGGGCCTCCATACCC CCATGCTCCATATGGTGCCGGCCGTGGGAACTATGATGCTTTTCGAGGCCAAGGCGGTTATCCTGGGAAA CCTCGGAACAGGATGGTTCGAGGAGACCCAAGGGCCATAGTGGAGTATCGGGACCTGGATGCCCCGGATG ATGTTGACTTCTTTTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001109909 |
| Insert Size | 2607 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001109909.1, NP_001103379.1 |
| RefSeq Size | 3018 bp |
| RefSeq ORF | 2607 bp |
| Locus ID | 83701 |
| UniProt ID | Q99MR6 |
| Gene Summary | Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) uses a different acceptor splice site at the penultimate exon compared to transcript variant 1, resulting in a shorter isoform (2) missing a 7 aa segment, compared to isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MR211012 | Srrt (Myc-DDK-tagged) - Mouse serrate RNA effector molecule homolog (Arabidopsis) (Srrt), transcript variant 2 |
CNY 8,650.00 |
|
| MR211012L3 | Lenti ORF clone of Srrt (Myc-DDK-tagged) - Mouse serrate RNA effector molecule homolog (Arabidopsis) (Srrt), transcript variant 2 |
CNY 10,550.00 |
|
| MR211012L4 | Lenti ORF clone of Srrt (mGFP-tagged) - Mouse serrate RNA effector molecule homolog (Arabidopsis) (Srrt), transcript variant 2 |
CNY 10,550.00 |
