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Wwc1 (NM_170779) Mouse Untagged Clone
CAT＃: MC223597
Wwc1 (untagged) - Mouse WW, C2 and coiled-coil domain containing 1 (Wwc1), (10ug)
CNY 14,160.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AA408228; AU017197; BC037006; Kibra; mKIAA0869 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC223597 representing NM_170779
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCCCGGCCGGAGTTGCCCCTGCCGGAGGGCTGGGAGGAGGCGCGCGACTTCGACGGCAAGGTCTACT ACATAGATCACAGGAACCGCACCACCAGCTGGATCGACCCGCGGGACAGGTACACCAAACCACTCACCTT CGCTGACTGCATCAGTGATGAGTTACCGCTGGGATGGGAAGAAGCATACGACCCACAGGTCGGAGATTAC TTCATAGACCACAATACCAAAACCACTCAGATCGAGGATCCAAGGGTGCAATGGCGGCGGGAACAGGAGC ACATGCTGAAGGATTACCTGGTGGTGGCTCAGGAAGCTCTGAGTGCACAAAAGGAGATCTACCAGGTGAA GCAGCAGCGCCTGGAGCTGGCACAGCAGGAGTATCAGCAGTTGCATGCCGTCTGGGAGCATAAGCTGGGC TCCCAGGTTAGCTTGGTCTCTGGATCCTCGTCCAGCTCCAAGTATGACCCCGAGATCCTGAAAGCTGAAA TTGCCACTGCAAAGTCCCGGGTCAACAAGCTGAAGAGAGAGATGGTTCACCTACAGCATGAGCTGCAGTT CAAGGAGCGTGGCTTTCAGACGCTGAAGAAAATTGATGAGAGAATGTCAGACGCACAGGGTGGCTACAAA CTGGATGAGGCCCAGGCTGTGCTGAGGGAAACCAAAGCCATCAAGAAAGCCATCACCTGCGGAGAAAAGG AGAAACAAGACCTCATTAAGAGTCTCGCCATGCTGAAGGATGGCTTCCGGACAGACAGAGGGTCACACTC CGACCTATGGTCCAGCAGCAGCTCTCTGGAGAGTTCAAGCTTCCCGATGCCAAAGCAGTTCCTGGACGTG AGCTCGCAGACAGACATCTCTGGGAGTTTCAGCACCAGCAGCAACAATCAGTTGGCCGAGAAGGTCAGAT TGCGCCTTCGGTATGAAGAGGCGAAGAGAAGGATCGCCAACCTCAAGATCCAGCTGGCCAAACTTGACAG TGAGGCCTGGCCTGGGGTGCTAGACTCAGAGAGGGACCGACTGATCCTCATCAATGAGAAGGAGGAACTT CTGAAGGAAATGCGCTTCATCAGCCCCCGGAAATGGACCCAGGGAGAGGTGGAGCAACTGGAGATGGCCC GGAGGCGACTTGAGAAGGACTTACAGGCAGCCCGGGACACCCAGAGCAAGGCGCTGACTGAGAGGCTGAA GTTAAATAGCAAGAGGAACCAGCTGGTGCGAGAACTGGAGGAAGCCACTCGGCAGGTGGCTACCCTGCAC TCCCAGTTGAAAAGCCTCTCAAGCAGCATGCAGTCCCTGTCTTCAGGCAGTAGCCCTGGGTCACTCACCT CCAGCCGGGGCTCCCTGGCCGCCTCTAGCCTGGACTCCTCCACCTCAGCCAGCTTCACTGACCTCTATTA TGACCCGTTCGAGCAGTTGGACTCGGAGCTCCAGAGCAAGGTGGAGCTGCTGTTCCTGGAGGGTGCCACG GGCTTCCGGCCCTCAGGCTGCATCACCACCATCCACGAGGATGAGGTGGCCAAGACCCAGAAGGCAGAGG GAGGCAGCCGCCTGCAGGCCCTGCGCTCCCTATCTGGCACTCCAAGGTCCATGACCTCCCTGTCTCCACG CTCATCTCTCTCCTCCCCATCCCCTCCCTGTTCCCCTCTCATCACTGATCCCCTCCTGACTGGAGATGCC TTCCTGGCCCCGCTGGAGTTTGAAGACACAGAGCTGAGTACCACTCTCTGTGAGCTGAACCTCGGCGGTA GCGGCACCCAGGAAAGATACCGGCTGGAGGAACCAGGACCTGAGGGCAAGCCACTGGGCCAAGCTGCAAG TGTGGCCCCAGGATGTGGCCTCAAAGTAGCCTGTGTGTCCGCTGCAGTGTCCGACGAGTCAGTAGCCGGG GACAGTGGCGTGTATGAGGCTTCAGCACAGAGACCAGGTACTTCTGAAGCTGCCGCATTCGACAGTGATG AATCGGAAGCTGTGGGTGCCACTCGGGTTCAGATTGCCCTGAAATATGATGAGAAGAATAAGCAATTTGC AATATTAATCATTCAGCTGAGTCACCTCTCTGCTCTGTCACTACAACAAGACCAGAAAGTGAACATCCGT GTAGCCATCCTGCCTTGCTCTGAAAGCAGCACCTGCTTGTTCAGAACCCGGCCTCTGGACTCGGCAAATA CCCTCGTGTTCAATGAGGCATTCTGGGTGTCCATCTCCTACCCAGCCCTTCACCAAAAGACCTTACGAGT CGATGTCTGCACCACTGACAGGAGCCATACAGAGGAGTGTCTGGGAGGTGCCCAGATCAGCCTGGCCGAG GTCTGCCGGTCTGGGGAGAGGTCAACGCGCTGGTACAATCTCCTGAGCTACAAATACTTGAAGAAGCAGT GCAGGGAGCCCCAGCCAACAGAAGCTCCAGGGCCAGACCATGTGGACGCTGTGTCTGCCTTGCTAGAACA GACAGCCGTGGAGCTAGAGAAGAGGCAGGAGGGAAGAAGCAGCTCCCAGACGCTGGAGGGCAGCTGGACG TACGAGGAAGAGGCCAGCGAGAATGAGGCAGTCGCTGAGGAGGAAGAGGAGGGAGAGGAAGATGTCTTCA CTGAAAAGGTCTCTCCCGAGGCAGAGGAGTGCCCAGCATTAAAGGTGGACAGAGAGACCAATACTGACAG CGTGGCCCCATCCCCCACAGTGGTGCGCCCTAAGGACCGGAGGGTGGGTGCCCCGTCGACAGGGCCATTT CTTCGAGGGAATACCATCATCCGCTCCAAGACCTTCTCGCCTGGACCCCAGAGCCAGTATGTGTGTCGGC TAAACCGCAGTGACAGTGATAGTTCTACGCTGTCCAAGAAGCCACCTTTTGTGCGAAACTCCCTGGAGCG GCGCAGCGTCAGGATGAAGCGGCCTTCCTCCGTCAAGTCCCTGCGCACAGAGCGTCTGATCCGCACCTCG CTGGACCTAGAACTCGACCTGCAGGCCACGAGGACCTGGCACAGCCAGCTGACTCAGGAGATCTCAGTGC TGAAGGAGCTGAAGGAGCATTTGGAGCAAGCCAAGAACCACGGGGAGAAGGAGCTGCCACAGTGGCTGCG TGAAGACGAGCGCTTCCGCTTGCTACTGAGGATGCTGGAGAAGAAGGTGGATCGTGGGGAGCACAAGAGT GAGTTGCAAGCCGACAAGATGATGAGAGCTGCTGCCAAGGATGTGCACAGGCTTCGAGGCCAGAGCTGTA AGGAGCCCCCAGAAGTGCAGTCTTTCAGGGAGAAAATGGCATTTTTCACCCGGCCTCGGATGAACATCCC AGCTCTCTCTGCAGATGACGTCTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_170779 |
| Insert Size | 3315 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_170779.1, NP_740749.1 |
| RefSeq Size | 3315 bp |
| RefSeq ORF | 3315 bp |
| Locus ID | 211652 |
| UniProt ID | Q5SXA9 |
| Gene Summary | Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ and may be associated with memory performance (By similarity). Regulates collagen-stimulated activation of the ERK/MAPK cascade.[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG220232 | Wwc1 (tGFP-tagged) - Mouse WW C2 and coiled-coil domain containing 1 (Wwc1), (10ug) |
CNY 12,160.00 |
|
| MR220232 | Wwc1 (Myc-DDK-tagged) - Mouse WW, C2 and coiled-coil domain containing 1 (Wwc1) |
CNY 11,020.00 |
|
| MR220232L3 | Lenti ORF clone of Wwc1 (Myc-DDK-tagged) - Mouse WW, C2 and coiled-coil domain containing 1 (Wwc1) |
CNY 12,920.00 |
|
| MR220232L4 | Lenti ORF clone of Wwc1 (mGFP-tagged) - Mouse WW, C2 and coiled-coil domain containing 1 (Wwc1) |
CNY 12,920.00 |
