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Zeb1 (NM_011546) Mouse Untagged Clone
CAT＃: MC223616
Zeb1 (untagged) - Mouse zinc finger E-box binding homeobox 1 (Zeb1), (10ug)
CNY 11,672.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 3110032K11Rik; AREB6; BZP; MEB1; Nil2; TCF-8; Tcf8; Tcf18; Tw; ZEB; Zfhep; Zfhx1a; Zfx1a; Zfx1ha |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC223616 representing NM_011546
Red=Cloning site Blue=ORF TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGATGGCCCCAGGTGTAAGCGCAGAAAGCAGGCGAACCCGCGGCGCAATAACGTTACAAATTATA ATACTGTGGTAGAAGCAAATTCAGATTCCGATGATGAAGACAAACTCCATATTGTGGAAGAAGAAAGTAT TACAGATGCAGCTGACTGTGAAGGTGGCATGCCAGATGATGAACTGCCAGCAGACCAGACAGTATTACCA GGAGGCAGTGACAGGGGGGGCGGTGCCAAGAACTGCTGGCAAGACAACGTGAAAGACAACGAGTGTGACT CAGATGCAGAAAATGAGCAAAACCATGATCCGAATGTGGAAGAATTTCTGCAGCAACAAGACACCGCCGT CATTTATCCTGAGGCGCCCGAGGAAGACCAGCGGCAGGGCACACCAGAAGCCAGCAGTCATGATGAAAAC GGAACACCAGATGCATTTTCCCAGTTGCTCACCTGCCCGTATTGTGATAGAGGCTACAAGCGCTTTACCT CTTTGAAAGAACACATTAAGTACCGCCATGAGAAGAACGAGGACAACTTCAGCTGCTCCCTGTGCAGTTA CACCTTTGCATACAGAACCCAGCTTGAACGTCATATGACATCACATAAGTCAGGAAGAGAGCAAAGACAT GTGACACAGTCTGGGGGAAACCGCAAGTTCAAGTGCACTGAATGCGGGAAGGCCTTCAAGTACAAACACC ACCTGAAAGAGCACTTACGGATTCACAGTGGAGAGAAGCCATACGAATGCCCGAACTGCAAGAAACGGTT TTCCCATTCTGGCTCCTATAGCTCACATATAAGCAGTAAGAAGTGTATTAGCTTGATGCCTGTGAATGGC AGGCCTAGATCAGGACTCAAGACATCTCAGTGTTCCTCGCCATCTCTTTCGACATCACCAGGCAGTCCCA CACGCCCACAGATACGACAGAAGATAGAGAATAAACCCCTTCAAGAACCGCTTTCTGTAAACCAAATCAA AACTGAACCTGTGGATTATGAGTTCAAACCCATAGTGGTTGCTTCAGGAATCAACTGTTCAACCCCTTTA CAAAATGGGGTTTTTAGCAGTGGTGGCCAATTGCAGGCAACCAGTTCTCCTCAGGGTGTGGTGCAAGCCG TTGTTCTGCCAACAGTTGGTTTGGTATCTCCCATAAGTATCAACTTAAGTGACATTCAGAATGTACTTAA AGTGGCTGTAGATGGTAACGTAATACGACAAGTCTTGGAGACTAATCAAGCCAGTCTTGCATCCAAAGAG CAAGAAGCAGTGAGTGCTTCGCCCATCCAGCAGGGTGGCCATTCTGTCATTTCTGCCATCAGTCTTCCTT TAGTTGATCAGGATGGAACAACCAAAATCATCATCAACTACAGTCTTGAGCAGCCCAGTCAACTTCAGGT TGTTCCCCAGAATTTAAAGAAAGAAATCCCAGCCCCTACAAACAGCTGCAAAAGTGAGAAGTTACCAGAA GACCTTACTGTCAAATCAGAAACGGACAAAAGCTTTGAGGGGGCCAGGGATGATAGCACTTGCCTTCTGT GTGAGGACTGCCCAGGGGACCTCAATGCACTTCCAGAACTAAAGCACTATGACCCAGAGTGCCCTGCTCA GCCTCCACCCCCTGCCCCAGCCACCGAGAAGCCAGAGTCCTCTGCTTCATCAGCTGGAAACGGAGATTTG TCTCCCAGTCAGCCACCTTTAAAGAACCTTCTGTCACTCTTGAAAGCCTACTATGCTCTGAACGCGCAGC CAAGCACAGAAGAGCTCTCAAAGATCGCCGATTCTGTGAACCTACCGCTGGATGGAGTTAAAAAGTGGTT TGAAAAGATGCAAGCTGGACAGATTCCAGGACAGTCTCCTGACCCCCCTTCTCCTGGAACCGGGTCAGTA AACATACCTACAAAAACCGATGAGCAGCCTCAACCTGCGGATGGAAATGAGCCCCAGGAAGACAGCACAC GCGGACAGAGTCCTGTCAAGATAAGGAGCTCTCCGGTTTTACCTGTAGGATCAGCCATGAACGGTTCCAG AAGCTGCACATCATCCCCATCCCCTCTAAACCTTTGCTCAGCCAGGAACCCGCAGGGTTACTCTTGTGTG GCAGAGGGTGCCCAGGAGGAGCCCCAAGTAGAACCTCTTGATCTCTCACTACCAAAGCAACAGGGAGAGT TACTGGAAAGGTCGACAGTCAGTAGCGTTTACCAGAACAGTGTTTATTCTGTCCAGGAAGAACCCTTGAA CTTGTCTTGTGCAAAAAAGGAACCACAAAAGGACAGCTGTGTTACAGACTCAGAACCAGTTGTAAATGTA GTCCCACCAAGTGCCAACCCCATAAACATTGCTATTCCTACAGTCACTGCCCAGTTACCCACAATCGTGG CCATTGCTGACCAGAACAGTGTTCCATGTTTAAGAGCACTGGCCGCCAACAAGCAGACTATTCTGATTCC CCAAGTGGCATATACATATTCAGCTACTGTGAGCCCTGCCGTGCAGGAGCCGCCAGTGAAGGTGATCCAG CCAAACGGAAACCAGGATGAAAGACAAGACACTAGCTCAGAAGGAGTCTCCACTGTGGAGGACCAGAATG ACTCTGACTCCACGCCACCCAAAAAGAAAACTCGGAAGACAGAGAATGGAATGTATGCATGTGACCTGTG TGACAAGATATTTCAGAAGAGCAGCTCACTGTTGAGACACAAATATGAGCACACAGGTAAGAGGCCTCAC GAGTGTGGAATCTGTAGAAAGGCATTTAAACACAAGCATCATTTGATTGAGCACATGCGGCTGCACTCTG GGGAAAAGCCCTATCAATGTGACAAGTGTGGCAAGCGCTTCTCACACTCCGGCTCCTACTCTCAACACAT GAATCACCGCTACTCCTACTGCAAGAGAGGAGCTGAAGACAGAGATGCTATGGAGCAGGAAGACGCTGGG CCCGAAGTCCTGCCGGAAGTCCTGGCGACTGAGCATGTTGGTGCCCGGGCGTCTCCCTCACAGGCTGACT CGGACGAGAGAGAAAGTCTGACAAGGGAAGAAGATGAAGACAGTGAAAAGGAGGAGGAGGAGGAAGATAA AGAGATGGAAGAATTACAGGAAGGAAAGGAATGTGAGAACCCACAGGGGGAGGAGGAGGAGGAGGAGGAG GAGGAAGAGGAGGAAGAAGAGGAGGAAGAGGAGGAAGTGGAAGCGGATGAAGCCGAGCATGAGGCAGCAG CCAAGACTGATGGTACAGTGGAGGTTGGAGCTGCACAGCAGGCAGGCAGCTTAGAGCAGAAGGCCAGCGA GAGCGAGATGGAGAGCGAAAGCGAGAGTGAGCAGCTGTCTGAAGAGAAGACAAATGAAGCTTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_011546 |
| Insert Size | 3354 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC139768, AAI39769 |
| RefSeq Size | 4814 bp |
| RefSeq ORF | 3354 bp |
| Locus ID | 21417 |
| UniProt ID | Q64318 |
| Gene Summary | Acts as a transcriptional repressor. Binds to E-box sequences in the immunoglobulin heavy chain enhancer as well as in the regulatory regions of many other tissue-specific genes. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1 (By similarity). Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.[UniProtKB/Swiss-Prot Function] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG223095 | Zeb1 (tGFP-tagged) - Mouse zinc finger E-box binding homeobox 1 (Zeb1), (10ug) |
CNY 13,272.00 |
|
| MR223095 | Zeb1 (Myc-DDK-tagged) - Mouse zinc finger E-box binding homeobox 1 (Zeb1) |
CNY 11,672.00 |
|
| MR223095L1 | Lenti ORF clone of Zeb1 (Myc-DDK-tagged) - Mouse zinc finger E-box binding homeobox 1 (Zeb1) |
CNY 14,072.00 |
|
| MR223095L2 | Lenti ORF clone of Zeb1 (mGFP-tagged) - Mouse zinc finger E-box binding homeobox 1 (Zeb1) |
CNY 14,072.00 |
|
| MR223095L3 | Lenti ORF clone of Zeb1 (Myc-DDK-tagged) - Mouse zinc finger E-box binding homeobox 1 (Zeb1) |
CNY 13,020.00 |
|
| MR223095L4 | Lenti ORF clone of Zeb1 (mGFP-tagged) - Mouse zinc finger E-box binding homeobox 1 (Zeb1) |
CNY 13,020.00 |
