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Sh3pxd2a (NM_008018) Mouse Untagged Clone
CAT＃: MC223641
Sh3pxd2a (untagged) - Mouse SH3 and PX domains 2A (Sh3pxd2a), transcript variant 1, (10ug)
CNY 14,350.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2310014D11Rik; AA589508; AI256723; AI413738; C230050L11; EG329070; Fish; Gm5098; Sh3md1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC223641 representing NM_008018
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCTCGCCTACTGCGTGCAAGATGCCACCGTGGTGGACGTGGAGAAGCGGAGGAGCCCCTCTAAACACT ATGTATACATTATCAACGTGACCTGGTCTGACTCCACCTCCCAGACTATCTACCGGAGGTACAGCAAGTT CTTCGACCTGCAGATGCAGCTTCTGGATAAGTTTCCTATTGAAGGTGGCCAGAAGGATCCGAAGCAAAGG ATTATTCCCTTTCTTCCAGGCAAGATCCTCTTCCGGAGAAGCCACATCCGCGACGTGGCTGTGAAGAGAC TAAAGCCCATCGATGAATACTGCAGGGCGCTTGTCCGGCTGCCGCCCCACATTTCACAGTGTGACGAAGT CTTCCGGTTCTTTGAGGCACGGCCTGAGGATGTCAACCCTCCAAAAGAAGACTATGGCAGTTCCAAGAGG AAATCAGTGTGGTTGTCCAGCTGGGCTGAGTCTCCCAAGAAGGACGTGACAGGTGCCGACACCAACGCCG AGCCCATGATCCTGGAACAGTACGTGGTGGTGTCCAACTATAAGAAACAAGAGAACTCGGAGCTGAGCCT CCAGGCCGGGGAGGTGGTAGATGTCATCGAGAAGAACGAAAGCGGCTGGTGGTTTGTGAGCACATCTGAA GAGCAAGGTTGGGTCCCCGCCACCTACTTGGAGGCCCAGAATGGCACACGAGACGACTCGGACATCAACA CCTCCAAGACTGGGGAAGTGTCCAAGAGACGCAAGGCACACCTGCGGCGCCTGGATCGCCGGTGGACCCT GGGCGGGATGGTCAACAGGCAGCACAGCCGAGAAGAGAAGTATGTCACTGTGCAGCCCTACACCAGCCAG AGCAAAGACGAGATCGGCTTCGAGAAGGGTGTCACCGTGGAGGTGATTCGAAAGAACCTGGAAGGCTGGT GGTACATCAGGTACCTCGGCAAAGAGGGTTGGGCACCAGCGTCCTACCTGAAGAAGGCCAAGGATGACCT GCCGACCCGGAAGAAGAACCTGGCGGGTCCGGTGGAGATCATAGGGAACATTATGGAGATCAGCAACCTT CTCAACAAGAAGGCATCTGGGGATAAGGAGGCTCCGGCTGAAGGCGAGGGATCCGAGGCCCCCATCACCA AGAAAGAGATCAGCTTACCGATCCTCTGCAACGCCTCCAATGGCAGCGCCTTGGCCATTCCCGAGAGGAC CACATCCAAGCTAGCCCAGGGCTCCCCAGCTGTGGCCAGGATCGCCCCTCAGAGGGCCCAGATCAGCTCC CCAAATCTGAGGACAAGACCTCCCCCGCGCAGAGAATCCAGCCTGGGGTTCCAGCTGCCAAAGCCGCCAG AGCCCCCTTCTGTTGAGGTAGAATACTACACCATTGCTGAATTCCAGTCCTGCATTTCTGACGGGATCAG CTTTCGAGGCGGACAGAAGGCAGAGGTCATCGACAAGAACTCGGGTGGTTGGTGGTACGTGCAGATCGGG GAGAAGGAGGGCTGGGCCCCAGCCTCATACATTGACAAGCGCAAGAAACCCAACCTCAGCCGCCGAACCA GCACTCTGACGCGGCCCAAGGTGCCGCCACCTGCGCCCCCCAGCAAGCCTAAGGAGGCCGAGGAGAATCC TGTGGGTGCCTGTGAGAGCCAGGGCTCCCCACTGAAGGTTAAATACGAGGAACCCGAGTATGACGTCCCT GCCTTTGGCTTTGACTCAGAGCCCGAGATGAATGAAGAGCCTTCAGGGGACAGAGGTTCAGGTGACAAGC ATCCCGCCCAGCCCCGAAGGATCTCGCCTGCCTCTTCCCTGCAACGGGCCCATTTCAAGGTGGGTGAGTC TTCTGAGGACGTGGCCCTGGAAGAGGAGACCATCTATGAGAATGAGGGCTTCAGGCCATACACAGAAGAC ACCCTGTCTGCCAGAGGCTCCTCTGGGGACAGTGACTCCCCTGGGAGCTCCTCTTTGTCCCTTGCCGTGA AAAACTCCCCTAAATCAGATTCCCCCAAATCCTCATCACTCCTAAAGCTCAAAGCAGAGAAGAATGCCCA GGCAGAACTGGGGAAAAACCAGTCCAACATCTCCTTCTCCTCCTCTGTCACCATCAGCACCACCTGTTCC TCCTCCTCATCCTCGTCCTCCTTGTCCAAGAACAATGGTGACCTGAAACCACGTTCTGCCTCAGATGCAG GTATCCGTGACACCCCTAAGGTTGGGACCAAGAAAGATCCTGATGTGAAGGCCGGGCTGGCCTCCTGCGC CCGAGCCAAGCCATCCGTGAGACCAAAGCCAGTCCTGAACCGAGCGGAGTCTCAAAGCCAGGAGAAGATG GATATTAGTTCCTTACGGCGCCAGCTGAGGCCCACAGGCCAGCTCCGGGGGGGCCTCAAGGGCTCTAGGA GTGAGGACTCAGAGCTGCCTCCACAGATGGCTTCTGAGGGATCCAGGCGAGGTTCTGCGGACATCATCCC TCTCACGGCCACCACTCCCCCGTGTGTCCCCAAAAAGGAATGGGAAGGGCAAGGCGCCACCTACGTGACG TGCAGCGCCTATCAGAAGGTCCAGGACTCGGAGATCAGCTTCCCCGAAGGCGCCGAGGTGCACGTGCTGG AGAAGGCGGAAAGTGGGTGGTGGTACGTGAGGTTTGGGGAGCTGGAGGGCTGGGCTCCTTCCCACTACTT GGTGGCCGAGGAGAACCAGCAACCTGACACAGCTAGCAAAGAGGGAGACACAGGAAAGAGCTCGCAGAAC GAGGGCAAGTCAGACAGCCTGGAAAAGATTGAGAAGCGTGTGCAGGCGCTCAACACTGTGAACCAGAGCA AGAGGGCCACCCCACCCATCCCCTCGAAGCCTCCCGGGGGCTTCGGCAAGACCTCGGGCACCGTAGCGGT GAAGATGAGGAACGGGGTCCGGCAAGTGGCCGTCAGGCCCCAATCTGTGTTTGTGTCTCCGCCACCCAAG GACAACAACCTGTCCTGTGCCCTTCGGAGGAACGAGTCGCTAACGGCCACCGACAGCCTCAGAGGTGTCC GCAGGAACTCCTCCTTTAGCACCGCACGGTCAGCAGCCGCTGAGGCCAAGGGCCGCCTGGCCGAGCGGGC TGCCAGCCAGGGCTCAGAATCGCCCCTGCTGCCTACCCAGCGCAAAGGCATCCCTGTCTCCCCCGTGCGT CCCAAGCCCATAGAGAAGTCCCAGTTTATCCACAACAACCTCAAGGATGTGTACATCTCGATTGCAGACT ATGAGGGGGACGAAGAGACGGCTGGCTTCCAGGAGGGGGTGTCCATGGAGGTGCTGGAGAAGAACCCCAA TGGCTGGTGGTACTGCCAGATCCTGGATGAGGTGAAGCCCTTCAAGGGCTGGGTACCCTCCAACTACCTT GAGAAGAAGAACTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_008018 |
| Insert Size | 3375 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_008018.4, NP_032044.2 |
| RefSeq Size | 10464 bp |
| RefSeq ORF | 3375 bp |
| Locus ID | 14218 |
| UniProt ID | O89032 |
| Gene Summary | Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG217612 | Sh3pxd2a (tGFP-tagged) - Mouse SH3 and PX domains 2A (Sh3pxd2a) transcript variant 1, (10ug) |
CNY 12,350.00 |
|
| MR217612 | Sh3pxd2a (Myc-DDK-tagged) - Mouse SH3 and PX domains 2A (Sh3pxd2a), transcript variant 1 |
CNY 11,210.00 |
|
| MR217612L3 | Lenti ORF clone of Sh3pxd2a (Myc-DDK-tagged) - Mouse SH3 and PX domains 2A (Sh3pxd2a), transcript variant 1 |
CNY 13,110.00 |
|
| MR217612L4 | Lenti ORF clone of Sh3pxd2a (mGFP-tagged) - Mouse SH3 and PX domains 2A (Sh3pxd2a), transcript variant 1 |
CNY 13,110.00 |
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