Adcy8 (NM_009623) Mouse Untagged Clone

CAT#: MC224054

Adcy8 (untagged) - Mouse adenylate cyclase 8 (Adcy8), (10ug)



  "NM_009623" in other vectors (4)

CNY 16,060.00


货期*
7周

规格
    • 10 ug

Product images

经常一起买 (2)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Synonyms AC8; AW060868
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MC224054 representing NM_009623
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGAGCTCTCGGATGTGCACTGCCTTAGTGGCAGCGAGGAACTCTACACCATCCAACCGACGCCCCCGG
CCGGCGACGACGGGAGCGGCTCTCGGCCGCAGCGGCTGCTGTGGCAGACGGCGGTGCGGCACATCACGGA
GCAGCGCTTCATCCACGGGCACCGAGGCGGCGGCGGCGGCGGGGTCTCCCGCAAAGCCTCGAACCCTGCG
GGCAGTGGACCCAATCACCACGCGCCGCAGCTGTCTAGCGACTCGGTGCTGCCTCTCTATTCTCTGGGCC
CCGGAGAGCGAGCGCACAACACCGGTGGCACCAAAGTCTTTCCGGAACGCAGCGGGAGCGGCAGTGCCAG
TGGCAGCGGGGGCGGGGGCGACTTGGGCTTCCTACACCTTGACTGTGCCCCAAGTAACTCGGATTTCTTC
CTCAATGGAGGATACAGCTACCGAGGGGTCATTTTTCCAACCCTACGCAACTCCTTCAAGTCTCGGGATC
TGGAGCGCCTCTACCAACGCTATTTCCTGGGCCAGAGGCGCAAATCGGAGGTAGTGATGAACGTGTTGGA
TGTACTAACCAAACTCACCCTTTTAGTCCTGCACTTGAGCCTGGCCTCGGCTCCAATGGACCCTCTCAAG
GGCATCCTGCTAGGCTTTTTCACTGGCATCGAGGTGGTGATCTGCGCCCTCGTGGTGGTCAGGAAGGACA
ACACCTCCCACACTTACCTGCAATACAGCGGCGTGGTCACTTGGGTGGCTATGACCACCCAGATTCTGGC
AGCAGGCCTGGGCTATGGGCTTCTGGGCGACGGCATAGGCTACGTGCTTTTTACACTCTTCGCCACCTAC
AGCATGCTTCCCCTGCCTCTCACCTGGGCCATCTTGGCCGGCCTGGGCACATCTTTGCTGCAAGTCACCC
TTCAAGTACTCATACCCAGGCTAGCGGTCTTTTCCATCAACCAGGTCCTGGCCCAGGTGGTGCTATTCAT
GTGTATGAATACAGCAGGAATCTTCATCAGTTACCTTTCAGACCGTGCCCAGCGCCAGGCCTTCCTGGAG
ACCCGGAGGTGTGTGGAGGCCAGGCTCCGCTTGGAGACAGAGAACCAAAGACAGGAGCGGCTTGTGCTGT
CTGTGCTCCCCAGGTTTGTCGTCCTGGAAATGATCAACGACATGACCAATGTGGAGGATGAGCACCTGCA
GCATCAGTTCCACCGCATCTACATCCATCGCTATGAGAACGTCAGTATTCTTTTTGCAGATGTCAAAGGA
TTTACCAACCTCTCTACGACCTTGTCTGCTCAGGAGCTGGTCAGGATGCTCAACGAACTCTTTGCCAGAT
TCGACCGGCTGGCCCATGAGCATCACTGTCTTCGCATTAAAATCCTGGGGGACTGCTACTACTGTGTGTC
TGGACTGCCTGAGCCCCGCCGGGACCACGCTCATTGCTGTGTTGAAATGGGCCTCAGCATGATCAAAACT
ATCAGGTTTGTGAGATCCAGAACGAAGCACGATGTTGACATGCGAATTGGAATCCATTCAGGTTCTGTGC
TATGTGGTGTGTTGGGCCTGAGGAAATGGCAGTTTGATGTCTGGTCTTGGGATGTGGACATAGCAAACAA
GCTTGAGTCTGGAGGAATCCCTGGGAGGATTCACATTTCTAAAGCCACCCTGGATTGCCTCAATGGTGAC
TATAACGTGGAAGAGGGTCACGGGAAAGAGAGGAACGAATTCTTGAGGAAGCATAACATAGAGACCTATT
TGATTAAGCAGCCTGAGGAGAGTTTGCTCTGCTTGCCTGAAGACATCGTTAAGGAGTCGGTGAGCTGCTC
TGACAGGAGAAACAGTGGAGCAACATTCACAGAAGGATCGTGGAGCCCAGAGCTGCCTTTCGACAACATC
GTGGGCAAACAGAATACTCTGGCTGCCCTAACAAGAAATTCAATAAATCTGCTTCCAAACCATCTCGCAC
AAGCTTTGCATGTCCAGTCTGGGCCTGAGGAAATTAACAAGAGAATAGAGCATACCATCGACTTGCGGAG
TGGCGATAAGTTGAGAAGAGAGCATATCAAGCCATTCTCACTGATGTTTAAAGACTCCAGCCTGGAGCAC
AAGTATTCTCAAATGAGGGATGAAGTATTCAAGTCAAACTTGGTCTGTGCATTTATCGTTCTTCTGTTTA
TCACTGCAATTCAAAGTTTGCTTCCTTCTTCAAGGCTGATGCCTATGACTATCCAGTTCTCCATCCTGAT
CATGCTGCACTCTGCCCTGGTCCTCATCACCACAGCAGAAGACTATAAGTGTCTGCCCCTCATCCTCCGA
AAAACCTGCTGTTGGATTAATGAGACCTATCTGGCCCGCAACGTCATCATCTTCGCTTCCATCTTAATTA
ACTTCCTGGGAGCTGTCCTAAATATTCTGTGGTGTGATTTTGACAAGTCGATACCCTTGAAGAACCTGAC
TTTCAATTCCTCAGCTGTGTTTACAGATATCTGCTCCTACCCAGAGTACTTTGTCTTCACTGGGGTGTTG
GCCATGGTGACCTGTGCTGTGTTTCTACGGCTTAACTCTGTCCTGAAGCTGGCAGTGCTACTCATCATGA
TCGCCATCTACGCCCTGCTCACAGAGACCATCTACGCAGGTCTCTTTCTGAGTTATGACAACCTGAACCA
CAGTGGAGAAGATTTCCTGGGGACCAAGGAAGCATCACTGCTGCTGATGGCCATGTTCCTTCTTGCTGTG
TTCTACCATGGACAACAGCTGGAGTACACAGCCCGCCTGGATTTCCTGTGGCGCGTACAGGCCAAAGAGG
AGATCAACGAGATGAAGGAACTGAGGGAACACAACGAGAACATGCTGCGCAATATCTTACCCAGCCATGT
GGCCCGCCACTTCCTGGAGAAAGACAGAGACAATGAGGAGCTGTATTCTCAATCCTACGATGCTGTTGGA
GTGATGTTCGCCTCCATCCCTGGGTTCGCAGACTTCTACTCTCAGACAGAAATGAACAACCAGGGAGTAG
AATGTCTGCGCTTGCTGAATGAGATCATTGCTGACTTTGATGAGCTGCTCGGGGAGGACCGGTTTCAGGA
CATTGAGAAGATTAAGACCATTGGTAGTACATACATGGCTGTCTCAGGACTGTCCCCAGAGAAACAGCAA
TGTGAAGATAAATGGGGACATTTGTGTGCCCTGGCTGACTTCTCTCTTGCTCTGACTGAAAGCATACAAG
AGATCAACAAGCATTCATTCAACAATTTTGAACTCCGAATCGGCATCAGCCATGGCTCAGTGGTGGCAGG
TGTAATTGGAGCTAAGAAACCACAGTATGACATTTGGGGGAAAACTGTGAACTTGGCAAGCCGAATGGAC
AGCACGGGAGTAAGTGGCCGGATCCAAGTTCCTGAGGAGACCTACCTTATCCTGAAGGACCAGGGCTTTG
CCTTTGACTACCGTGGGGAGATATATGTGAAGGGCATCAGTGAACAAGAAGGGAAAATCAAAACATACTT
TCTCCTGGGACGAGTCCAACCCAACCCATTCATCTTACCCCCAAGGAGACTTCCCGGGCAATACTCTCTG
GCTGCGGTTGTCCTTGGCCTTGTCCAGTCTCTCAACAGGCAAAGGCAGAAGCAACTTCTCAACGAGAACA
GCAATTCGGGCATCATCAAGAGCCATTACAACCGGCGGACTTTGCTAACGCCAAGTGGGCCAGAGCCTGG
AGCACAAGCTGAAGGCACTGACAAATCCGATTTGCCATAA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI     
ACCN NM_009623
Insert Size 3750 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_009623.2, NP_033753.2
RefSeq Size 5064 bp
RefSeq ORF 3750 bp
Locus ID 11514
UniProt ID P97490
Gene Summary Catalyzes the formation of cAMP in response to calcium entry leadings to cAMP signaling activation that affect processes suche as synaptic plasticity and insulin secretion (PubMed:10864938, PubMed:25403481, PubMed:10482244, PubMed:14585998, PubMed:18448650). Plays a role in many brain functions, such as learning, memory, drug addiction, and anxiety modulation through regulation of synaptic plasticity by modulating long-term memory and long-term potentiation (LTP) through CREB transcription factor activity modulation (PubMed:10482244, PubMed:14585998, PubMed:18448650, PubMed:10864938, PubMed:12441059, PubMed:20638449, PubMed:27234425, PubMed:18222416). Plays a central role in insulin secretion by controlling glucose homeostasis through glucagon-like peptide 1 and glucose signaling pathway and maintains insulin secretion through calcium-dependent PKA activation leading to vesicle pool replenishment (PubMed:25403481). Also, allows PTGER3 to induce potentiation of PTGER4-mediated PLA2 secretion by switching from a negative to a positive regulation, during the IL1B induced-dedifferentiation of smooth muscle cells (By similarity).[UniProtKB/Swiss-Prot Function]
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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