Rb1cc1 (NM_009826) Mouse Untagged Clone
CAT#: MC224720
Rb1cc1 (untagged) - Mouse RB1-inducible coiled-coil 1 (Rb1cc1), (10ug)
CNY 10,872.00
Product images
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | 2900055E04Rik; 5930404L04Rik; Cc1; FIP200; LaXp180 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>NCBI ORF sequence for NM_009826, the custom clone sequence may differ by one or more nucleotides
ATGAAGTTATATGTGTTTCTGGTTAACACCGGAACCACGCTGACATTTGACACTGAGCTAACTGTGCAAA CTGTGGCTGATCTTAAGCATGCCATTCAAAGCAAATACAAGATTGCTATTCAGCACCAGGTTCTGGTGGT CAATGGAGGAGAATGCATGGCTGCAGATCGAAGAGTGTGTACTTACAGCGCTGGGACGGACACAAATCCA ATTTTTCTTTTTAATAAAGAAATGATCTTATGTGACCGTGCACCTGCTATTCCTAAAGCTACCTTTTCAA CAGAAAATGACATGGAAATAAAAGTTGAAGAGTCTCTTATGATGCCTGCAGTTTTCCACACTGTTGCTTC AAGGACACAGCTTGCAGTGGAAATGTATGACGTTGCCAAGAAGCTCTGCTCTTTCTGTGAAGGGCTTGTC CATGATGAACATCTTCAGCACCAAGGCTGGGCTGCAATCATGGCCAATCTGGAGGACTGTTCAAATTCAT ACCAAAAACTTCTTTTCAAGTTTGAAAGTATTTATTCTGATTATCTTCAATCCATAGAAGACATCAAGTT AAAACTTACTCATTTAGGAACTGCTGTTTCAGTAATGGCCAAGATTCCACTATTGGAGTGCCTAACCAGA CATAGTTACAGGGAATGTTTGGGAAGACCGGATTCTTTGAATGAACATGAAGGCTCAGAGAAAGCTGAGA TGAAAAGATCTACTGAATTGGTGCTCTCTCCTGATATGCCTAGAACATCGAACACATCCTTGGTAACCTC ATTTCACAAGTCAATGGAGCATGTAGCTCCAGATCCCACCGGTACTGAACGTGGCAAAGAACTTAGGGAA TCTTGTCAAAGTACTGTCCAGCAAGAAGAAGCTTCAGTGGATGCTAAAGACAGTGATCTGCCTTTTTTTA ATGTTTCTTTGTTAGACTGGATAAATGTTCAAGATAGACCCAATGATGTGGAATCTCTGGTCAGGAAGTG CTTTGATTCTATGAGCAGGCTTGACCCAAAGATTATTCAACCATTTATGTTAGAATGCCATCAAACTATT GCCAAACTTGATAATCAGAATATGAAAGCCATTAAAGGGCTTGAAGATCGGCTGTATGCCTTGGACCAGA TGATTGCTAGCTGTAGCCGGCTGGTAAATGAACAGAAAGAGCTTGCTCAGGGATTTTTAGCTAATCAGAT GAGAGCTGAAAACTTGAAGGATGCATCTGTGTTACCTGATCTGTGTCTGAGTCATGCAAATCAACTAATG ATTATGTTGCAAAACCACAGAAAACTGTTGGATATTAAACAGAAGTGCACCACTGCCAAACAAGAGCTAG CAAACAATCTCCACGTCAGACTGAAGTGGTGTTGTTTTGTGATGCTTCATGCTGATCAAGATGGAGAAAA ACTGCAGGCACTGCTCCGCCTTGTAATAGAGCTGTTAGAAAGAGTCAGAATTGTTGAGGCTCTTAGTACA GTTCCTCAGATGTATTGCCTAGCTGTTGTTGAGGTTGTAAGAAGAAAAATGTTCATTAAACACTACAGAG AGTGGGCTGGTGCTTTAGTCAAAGACGGAAAACAACTATATGAAGCTGAAAAGTCAAAAAGGGAATCCTT TGGGAAATTATTTAGGAAGTCCTTTTTAAGAAATCGTCTGTTTAAAGGACTGGACTCCTGGCCTTCCTCA TTTTGTACTCAGAAGCCTCGAAAATTTGACTGTGAACTTCCAGATATATCGTTAAAAGATTTACAGTTTC TTCAATCATTTTGTCCTTCAGAAGTGCAGCCATTCCTCAGGGTCCCCTTACTTTGTGACTTTGAACCTCT ACACCAGCATGTACTTGCCCTACATAATTTGGTAAAAGCAGCACAAAGTTTGGATGAAATGTCACAGACT ATTACAGATCTCCTAAATGAACAAAAGGTATCCACAAGTCAGGCATCCCCACAGTCAGCTGCTTCTCCAA GAATAGAAAGTACAACAGGCATTACAACCACTACCTCACCAAAAACTCCTCCTCCACTAACTGTTCAGGA CACCTTATGTCCGGCAGTGTGTCCCTTAGAAGAATTATCTCCAGATAGTATCGATGCTCATACATTTGAT TTTGAAACCATCTCCCATCCAAACACAGAACAACCTGTTCACCAAGCTTCTATAGACTTGGATTCATTAG CAGAAAGCCCTGAGTCTGACTTTATGTCTGCTGTGAATGAGTTTGTGATAGAAGAAAATTTATCGTCTCC AAACCCTATAAGTGATCCACAAAGTCCAGAAATGATGGTGGAGTCACTTTACTCTTCAGTCATCAATGCA ATAGATAGTAGGCGTATGCAAGACACAAGTACACGTGGAAACGAGGGCTTTGGGGATCGGGCTGCTCTAC ATGTCCAGCTGGAGAAATGCAGAGCTGCTGCACAAGACTCTCACAGCAGTATACAAACCATCAAGGACGA TCTGTGCCATTTCAGAACATTTGTACAAAAAGAACAGTGTGACTTAGCAAATTATTTAAAATGTACAGCT GTAGAAATAAGAAATATTATTGAAAAAGTAAAATGTTCTCTAGAAATAACACTAAAGGAAAAGCATCAGC AAGAACTCCAATCTTTAAAAATTGAGTATGAATGTAAACTTGATGCTCTAGTAAAAGACAGTGAAGAAAA TGTAAATAAAATTTTAAAATTGAAAGAAAATTTAGTATCCCTTGAAGAGGCTTTACAAAATAAAGACAAT GAATTCACTTCGATTAAACATGAAAAGGATGCTATTGTCTGTGTGCAGCAAGAAAAGGATCAGAAGTTGT TAGAGATGGAAAAGATAATGCATACTCAACATTGTGAAATTAAAGAACTGAAGCAGTCACGAGAGATGGC ATTAGAAGACCTGAAAAAGCTGCATGATGAAAAAATCGAGTCATTGAGAGCTGAATTTCAGTGCTTAGAA CAAAATCACCTGAAGGAATTAGAGGACACACTGCACATCAGGCACACACAGGAGTTTGAGAAAGTTATGA CAGACCACAATATGTCTTTGGAGAAATTAAAAAAAGAAAATCAGCAAAGAATTGACCAGATGCTAGAATC TCATGCCTCAACTATTCAGGAAAAAGAGCAACAGCTGCAGGAGTTGAAACTCAAAGTTTCTGACTTGTCA GACATGAGATGTAAGTTAGAGGTTGAACTTGCACTAAAGGAAGCAGAAACAGATGAGATAAAGATCTTGT TGGAAGAGAGCAGAACACAGCAGAAGGAAATGCTGAAGTCTTTACTTGAACAAGAGACCGAAAACTTAAG AACAGAAATAAGTAAACTAAACCAAAAAATTCATGATAATAATGAGAGTTACCAGGTGGGTTTGTCAGAG TTAAGAGCTTTAATGACAATTGAAAAAGATCAGTGCATTTCAGAGTTAATCAGTAGACATGAAGAAGAAT CTAATATACTTAAGGCTGAATTAGACAATGTTACATCTTTGCATCGCCAAGCATTTGAAATAGAAAAAAA ACTGAAAGAACAAATAGTTGAATTGCAGACTAGATTGAACTCAGAATTGAGTGCTCTTGAAAAACAGAAA GATGAAAAAATAACCCAACAAGAAGAGAAGTATGAAGCACGTATCCAGAACCTTGAGAAAGACAAGGAGA GACTGGTCAAGAACCACGAGCAAGACAAAGAACACTTAATTCAGGAGCTTAATTTTGAAAAAAACAAAGC TGTTCAAACTGCACTAGATGAATTTAAGGTGGAGAGAGAACTTGTTGAGAAAGAGTTATTAGAAAAAGTT AAACATCTTGAGAATCAAATAGCCAAAACTCCTGCCTTTGAGTCAGCCAGAGAAGATTCTTCAAGCTTAG TTGCGGAACTTCAAGAGAAACTTCAAGAAGAAAAAGCTAAGTTTCTGGAACAACTTGAAGAACAAGAGAA AAGAAAGAATGAGGAAATGCAAAATGTCAGAACCTCTTTGATTGCTGAGCAGCAGACCAACTTTAACACA GTCTTAACAAGAGAGAAAATGAGGAAAGAAAACATAATAAATGATCTTAGTGATAAGCTAAAAAGTACAA TGCAGCAGCAAGAGCGGGATAAAGATTTGATAGAGTCGCTCTCTGAGGACCGAGCTCGTTTGCTTGAAGA GAAGAAGCAGCTTGAAGAGGAAGTGAGTAAACTCCGCACTAGCAGTTTTCTTTCCTCAGCACCTGTGGCT GCAGCCCCAGAGCTCTATGGTGCGTGTGCACCTGAGCTCCCAGGGGAGCCAGAGAGATCAGTCATGGAGA CGGCAGATGAAGGAAGACTGGATTCCGCAATGGAGACAAGCATGATGTCTGTCCAAGAAAACATGTTATC TGAAGAGAAGCAGAGGATCATGCTCCTAGAACGGACATTGCAGTTGAAAGAAGAAGAAAACAAGCGGTTA AATCAAAGACTGATGTCTCAGAGTTTGTCCTCAGTCTCTTCAAGGCATTCTGAAAAAATAGCCATTAGAG ATTTTCAGGTGGGAGATTTGGTTCTCATCATCCTAGATGAGCGGCACGACAATTATGTATTGTTTACTGT TAGTCCTACTTTATATTTTCTGCACTCAGAGTCTCTTCCTGCCCTGGATCTCAAACCAGGTGAGGGAGCT TCAGGTGCATCTAGAAGACCCTGGGTCCTTGGGAAAGTAATGGAAAAGGAATACTGTCAAGCCAAAAAGG CACAAAACAGATTTAAAGTTCCTTTGGGGACAAAGTTTTACAGAGTGAAAGCTGTGTCATGGAATAAGAA AGTATAG |
Restriction Sites | SgfI-MluI |
ACCN | NM_009826 |
Insert Size | 4767 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | BC150774, AAI50775 |
RefSeq Size | 5132 bp |
RefSeq ORF | 4767 bp |
Locus ID | 12421 |
UniProt ID | Q9ESK9 |
Gene Summary | Involved in autophagy (PubMed:23262492, PubMed:19258318). Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1 (PubMed:23392225, PubMed:23285000, PubMed:19258318). Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) during S.typhimurium infection and subsequent xenophagy (PubMed:21525242). Involved in repair of DNA damage caused by ionizing radiation, which subsequently improves cell survival by decreasing apoptosis (PubMed:21807966). Inhibits PTK2/FAK1 and PTK2B/PYK2 kinase activity, affecting their downstream signaling pathways (By similarity). Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111 (PubMed:21795712). Functions as a DNA-binding transcription factor (PubMed:12095676). Is a potent regulator of the RB1 pathway through induction of RB1 expression (PubMed:15968549). Plays a crucial role in muscular differentiation (PubMed:15968549). Plays an indispensable role in fetal hematopoiesis and in the regulation of neuronal homeostasis (PubMed:19940130, PubMed:21088496).[UniProtKB/Swiss-Prot Function] |
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Product Manuals |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG216914 | Rb1cc1 (tGFP-tagged) - Mouse RB1-inducible coiled-coil 1 (Rb1cc1), (10ug) |
CNY 13,300.00 |
|
MR216914 | Rb1cc1 (Myc-DDK-tagged) - Mouse RB1-inducible coiled-coil 1 (Rb1cc1) |
CNY 10,872.00 |
|
MR216914L3 | Lenti ORF clone of Rb1cc1 (Myc-DDK-tagged) - Mouse RB1-inducible coiled-coil 1 (Rb1cc1) |
CNY 13,970.00 |
|
MR216914L4 | Lenti ORF clone of Rb1cc1 (mGFP-tagged) - Mouse RB1-inducible coiled-coil 1 (Rb1cc1) |
CNY 13,970.00 |