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Thoc2 (NM_001033422) Mouse Untagged Clone
CAT＃: MC224729
Thoc2 (untagged) - Mouse THO complex 2 (Thoc2), (10ug)
CNY 20,430.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 6330441O12Rik; D130005M13Rik; Gm1139; Gm1793; Tho2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC224729 representing NM_001033422
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGCCGCGGCTGTGGTGGTTCCCGCAGAGTGGATAAAGAACTGGGAGAAATCAGGGAGAGGCGAAT TTTTACATTTATGCCGGATTCTCAGTGAAAATAAAAGCCATGACAGTTCGACCTACAGAGATTTTCAACA AGCTCTGTATGAGTTGTCATACCATGTCATTAAAGGGAATTTAAAGCACGAACAGGCATCTAGTGTTCTT AATGACATTAGCGAATTCCGTGAGGATATGCCTTCTATCCTTGCTGACGTGTTCTGCATATTAGATATTG AAACAAATTGTTTAGAAGAAAAAAGCAAGAGAGACTATTTTACACAGTTGGTATTAGCATGTTTGTATTT AGTTTCAGACACAGTTTTGAAGGAACGATTGGATCCAGAAACTTTGGAATCATTAGGGCTTATCAAACAG TCACAGCAGTTCAACCAAAAGTCAGTTAAAATCAAGACAAAACTCTTTTATAAGCAGCAAAAATTCAATT TATTAAGAGAAGAAAATGAAGGTTATGCCAAGCTGATTGCTGAACTGGGACAAGATTTATCTGGAAATAT TACTAGTGATTTAATATTAGAAAATATCAAATCTTTAATCGGATGCTTTAATCTGGATCCTAATAGAGTT TTGGATGTCATTTTAGAAGTGTTTGAATGCAGGCCAGAACATGATGACTTCTTTATATCTTTATTAGAAT CTTACATGAGTATGTGTGAGCCACAAACACTGTGTCATATTCTTGGATTCAAATTCAAGTTTTACCAGGA ACCAAGTGGTGAGACGCCATCGTCTTTATACAGAGTTGCAGCAGTCCTCCTGCAATTTAATCTCATTGAT CTAGATGATCTTTATGTGCATCTCCTTCCTGCTGATAATTGTATTATGGATGAATACAAACGAGAAATTG TGGAAGCTAAGCAAATTGTAAGAAAACTCACAATGGTTGTGCTGTCTTCTGAAAAACTTGATGAACGAGA CAAAGAAAAGGACAAAGATGATGAGAAAGTTGAGAAGCCACCGGACAACCAAAAGCTGGGTTTGTTGGAA GCTTTGTTAAAAGTTGGTGATTGGCAGCATGCACAGAACATCATGGATCAGATGCCTCCATACTATGCAG CTTCACATAAACTAATAGCTCTTGCTATTTGCAAGCTCATTCACATAACCGTTGAGCCTCTCTACCGAAG AGTTGGTGTTCCTAAAGGTGCTAAGGGCTCACCGGTTAGCGCTTTGCAAAACAAGAGAGCACCGAAGCAA GTAGAGAGCTTTGAAGATTTGAGGAGGGATGTATTCAATATGTTCTGTTACCTTGGTCCTCACCTCTCAC ATGATCCCATTTTATTTGCAAAAGTCGTGCGCATAGGCAAGTCATTTATGAAGGAGTTTCAGTCTGATGG AAGCAAACAGGAAGATAAAGAGAAAACGGAAGTTATCCTTAGCTGTTTGCTTAGCATTACTGACCAGGTA TTACTTCCATCTCTTTCTTTGATGGACTGCAATGCTTGCATGTCTGAGGAGCTGTGGGGAATGTTTAAGA CATTTCCCTATCAGCATAGATATCGACTATATGGTCAGTGGAAGAATGAAACTTATAATGGTCACCCACT TTTAGTAAAAGTTAAAGCTCAAACAATAGACAGAGCCAAGTATATCATGAAGCGTCTAACCAAGGAAAAT GTGAAGCCTTCAGGAAGACAAATTGGCAAGCTGAGCCACAGCAATCCAACAATTTTGTTTGATTATATCT TGTCACAAATCCAGAAATACGATAACTTAATAACACCTGTAGTAGATTCATTGAAATACCTCACTTCGTT GAATTATGATGTCTTGGCCTATTGTATCATTGAAGCTTTAGCTAATCCAGAAAAGGAAAGAATGAAACAT GATGACACAACCATCTCAAGCTGGCTTCAGAGTCTGGCTAGTTTCTGTGGTGCAGTATTCCGTAAATACC CGATTGATCTTGCTGGTCTTCTTCAGTATGTAGCCAATCAATTAAAGGCAGGCAAAAGTTTTGACCTACT AATATTGAAAGAAGTGGTACAAAAAATGGCAGGAATTGAAATTACAGAGGAGATGACGATGGAGCAGTTA GAAGCCATGACTGGTGGGGAGCAGCTAAAGGCTGAGGGTGGTTATTTCGGCCAGATCAGAAACACTAAAA AATCTTCTCAGAGATTAAAGGATGCACTACTGGACCATGATCTTGCTCTTCCTCTCTGTTTGCTTATGGC ACAACAGAGAAATGGGGTAATTTTTCAGGAGGGTGGAGAGAAACACTTGAAACTTGTGGGGAAACTCTAT GACCAGTGTCATGACACCCTAGTACAGTTTGGTGGATTTTTAGCATCAAATCTAAGTACAGAAGATTATA TAAAACGAGTGCCTTCAATTGATGTGCTCTGTAATGAGTTTCATACACCACACGATGCAGCATTTTTTCT GTCTAGGCCAATGTATGCACACCATATTTCGTCAAAATACGATGAACTTAAAAAATCAGAAAAGGGAAGT AAACAGCAACATAAAGTCCATAAATACATTACATCATGTGAGATGGTGATGGCTCCTGTCCATGAAGCAG TGGTCTCCTTACATGTTTCCAAAGTCTGGGATGACATCAGTCCTCAGTTCTATGCTACATTTTGGTCATT GACAATGTATGACCTTGCAGTTCCACATACCAGCTATGAAAGAGAAGTCAATAAACTTAAAGTCCAGATG AAAGCGATTGATGACAATCAGGAAATGCCTCCAAATAAAAAGAAAAAAGAAAAGGAGCGTTGCACTGCCC TTCAGGACAAGCTCCTTGAAGAAGAAAAGAAGCAGATGGAACATGTTCAAAGAGTACTTCAGAGACTGAA ACTAGAAAAGGACAACTGGCTTTTAGCAAAGTCTACCAAAAATGAGACCATCACAAAATTTTTACAGCTG TGTATATTTCCTCGATGCATTTTTTCAGCAATTGATGCTGTTTATTGTGCTCGTTTTGTTGAATTGGTAC ATCAACAGAAAACTCCAAATTTTTCCACACTTCTTTGCTATGATCGAGTTTTTTCTGACATAATTTACAC GGTTGCAAGCTGCACTGAAAATGAAGCTAGTCGGTATGGGAGATTTCTTTGCTGTATGTTAGAGACGGTG ACCAGGTGGCATAGTGATAGAGCCACATATGAAAAGGAATGTGGAAACTATCCAGGATTCCTTACCATAT TACGGGCAACTGGATTTGATGGTGGAAATAAAGCTGATCAGTTAGATTATGAAAATTTTCGACACGTTGT CCACAAATGGCATTACAAACTAACCAAGGCATCAGTACATTGCCTTGAGACGGGCGAATATACTCACATC AGGAATATATTGATTGTACTAACAAAAATACTTCCTTGGTACCCAAAAGTTTTGAATCTGGGTCAGGCTT TGGAGAGAAGAGTGAATAAAATATGCCAAGAAGAAAAAGAGAAGAGGCCAGATCTTTATGCATTGGCTAT GGGCTACTCGGGGCAGTTGAAAAGTAGAAAGTCACACATGATACCTGAAAATGAATTTCATCATAAGGAT CCTCCTCCAAGGAATGCTGTTGCCAGTGTACAAAATGGGCCTGGTGGTGGGACTTCTTCATCATCTATAG GAAATGCATCTAAATCAGATGAAAGCGGTGCTGAGGAGACTGATAAATCAAGGGAGAGATCTCAGTGTGG TACAAAAGCTGTTAATAAGGCTTCTAGTACCACACCAAAGGGGAATTCAAGCAATGGAAATAGTGGCTCT AACAGCAACAAAGCTGTTAAGGAAAATGACAAAGAAAAAGTAAAAGAGAAAGAAAAAGAGAAAAAGGAGA AGACTCCAGCTACAACTCCAGAGGCCAGGGCACTTGGTAAAGATAGTAAAGAAAAACCGAAGGAAGAGCG GCCAAATAAAGAAGACAAAGCAAGAGAGACAAAGGAAAGAACACCTAAATCTGACAAAGAGAAAGAGAAG TTCAAGAAGGAAGAAAAAGCTAAAGATGAGAAATTCAAGACTACCGTCCCCATCGTAGAATCAAAATCGA CTCAAGAAAGGGAAAGAGAGAAGGAGCCATCCAGAGAAAGAGATGTAGCAAAGGAAATGAAGTCAAAGGA AAATGTTAAAGGAGGAGAAAAAACACCAGTTTCAGGGTCCTTGAAGTCACCTGTTCCCCGATCAGATATC TCGGAGCCTGACAGGGAACAAAAACGCCGCAAAATTGATAGTCATCCTTCTCCATCACATTCCTCCACAG TAAAGGACAGTCTCATCGATCTCAAGGACTCTTCAGCAAAGCTCTACATTAACCATAACCCTCCACCACT GTCCAAGAGTAAGGAGAGAGAAATGGACAAGAAAGATTTGGACAAGTCAAGGGAAAGATCCAGAGAAAGA GAGAAAAAAGATGAAAAGGACAGGAAAGAACGGAAAAGGGATCATTCAAACAATGACCGCGAAGTGCCAC CGGACATAACAAAGAGGCGGAAAGAGGAGAATGGAACAATGGGGGTTTCAAAACACAAAAGTGAGAGTCC ATGTGAGTCTCAATATCCAAATGAGAAAGACAAAGAGAAAAATAAGTCAAAATCTTCAGGCAAAGAAAAA AGCAGTAGTGATTCGTTTAAGTCTGAGAAGATGGATAAAATCTCATCTGGTGGCAAAAAGGAATCCAGGC ATGATAAAGAAAAGATAGAAAAGAAAGAAAAACGGGATAGTTCAGGAGGAAAGGAAGAGAAGAAACATCA TAAGTCCTCTGACAAGCACAGATAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001033422 |
| Insert Size | 4785 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001033422.1, NP_001028594.1 |
| RefSeq Size | 7631 bp |
| RefSeq ORF | 4785 bp |
| Locus ID | 331401 |
| UniProt ID | B1AZI6 |
| Gene Summary | Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. Plays a role for proper neuronal development.[UniProtKB/Swiss-Prot Function] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG214444 | Thoc2 (tGFP-tagged) - Mouse THO complex 2 (Thoc2), (10ug) |
CNY 17,480.00 |
|
| MR214444 | Thoc2 (Myc-DDK-tagged) - Mouse THO complex 2 (Thoc2) |
CNY 15,870.00 |
|
| MR214444L3 | Lenti ORF clone of Thoc2 (Myc-DDK-tagged) - Mouse THO complex 2 (Thoc2) |
CNY 17,770.00 |
|
| MR214444L4 | Lenti ORF clone of Thoc2 (mGFP-tagged) - Mouse THO complex 2 (Thoc2) |
CNY 17,770.00 |
