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Lrp6 (NM_008514) Mouse Untagged Clone
CAT＃: MC224752
Lrp6 (untagged) - Mouse low density lipoprotein receptor-related protein 6 (Lrp6), (10ug)
CNY 20,710.00
货期*
8周
规格
Product images
经常一起买 (2)
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | C030016K15Rik; Cd; Gw; ska26; ska |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC224752 representing NM_008514
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGGGCCGTGCTGAGGAGCCTCCTGGCCTGCAGCTTCTGCGTGCTGCTGAGAGCGGCCCCTTTGTTGC TTTATGCAAACAGACGGGACTTGAGATTGGTTGATGCTACAAATGGCAAAGAGAATGCAACGATTGTAGT TGGAGGCTTGGAGGATGCAGCTGCGGTGGACTTTGTGTTTGGTCATGGCTTGATATACTGGAGTGATGTC AGCGAAGAAGCCATTAAACGAACAGAATTTAACAAAACTGAAAGTGTACAGAATGTTGTTGTTTCTGGAT TATTGTCCCCGGATGGGCTGGCATGTGATTGGCTTGGAGAAAAATTGTACTGGACAGATTCTGAAACTAA TCGTATTGAAGTTTCTAATTTAGATGGATCTTTACGAAAAGTTTTATTTTGGCAAGAGTTGGATCAACCC AGAGCTATTGCCTTAGATCCATCAAGTGGGTTCATGTACTGGACAGACTGGGGAGAAGTGCCAAAGATAG AACGTGCTGGGATGGATGGCTCAAGTCGCTTCGTTATAATAAACACAGAGATTTACTGGCCAAACGGACT GACTCTGGACTATCAGGAGCGGAAGCTTTACTGGGCCGATGCAAAACTTAATTTCATCCATAAATCAAAC CTGGATGGAACAAACCGGCAGGCAGTGGTTAAAGGTTCCCTTCCACATCCTTTTGCCTTGACGTTATTTG AGGACACATTGTACTGGACTGACTGGAATACACACTCTATTTTGGCTTGCAACAAATATACTGGCGAGGG TCTGCGTGAAATTCATTCTAACATCTTCTCTCCCATGGATATACATGCTTTCAGCCAACAGAGGCAGCCA AATGCTACAAATCCATGTGGAATTGATAATGGTGGTTGTTCCCATTTGTGTTTGATGTCTCCAGTCAAGC CTTTTTATCAGTGTGCTTGCCCAACTGGGGTCAAGCTGCTGGAGAATGGAAAGACCTGCAAAGATGGTGC CACTGAACTATTGCTGTTAGCCCGACGGACAGACTTGAGGCGAATTTCTTTGGATACACCCGATTTTACT GACATTGTTCTGCAGTTAGAAGATATCCGGCATGCCATTGCCATAGACTATGACCCTGTAGAAGGCTACA TATACTGGACGGATGACGAAGTGAGGGCTATCCGTCGCTCCTTCATAGATGGATCTGGCAGTCAGTTTGT GGTCACGGCCCAGATTGCTCATCCTGATGGTATTGCTGTTGACTGGGTTGCAAGGAACCTGTACTGGACA GACACTGGCACGGATCGTATAGAAGTGACAAGGCTCAATGGGACCATGAGGAAGATCTTGATTTCAGAGG ACTTAGAGGAGCCCCGGGCTATCGTGTTAGATCCCATGGTTGGGTACATGTATTGGACAGACTGGGGAGA AATCCCAAAAATAGAGCGAGCTGCTCTGGACGGATCTGACCGAGTAGTTCTTGTCAACACTTCCCTTGGT TGGCCAAACGGCTTAGCCCTGGATTATGATGAAGGCACAATATACTGGGGAGATGCCAAAACAGACAAAA TTGAGGTTATGAATACCGATGGCACCGGGAGGCGAGTGCTGGTGGAAGACAAGATCCCTCACATATTTGG GTTTACCTTGCTGGGTGACTATGTTTACTGGACTGACTGGCAGAGGCGGAGCATCGAGAGAGTACACAAA CGGAGCGCAGAGAGGGAGGTCATCATAGATCAGCTGCCAGACCTCATGGGACTGAAGGCCACAAGTGTTC ACAGAATCATTGGTTCTAACCCCTGTGCTGAGGACAATGGAGGATGTAGCCATCTTTGCCTGTACAGGCC TCAGGGGCTTCGATGCGCCTGTCCCATTGGCTTTGAGCTCATCAGTGACATGAAGACATGCATTGTCCCC GAGGCTTTCCTTCTGTTCTCGAGGAGAGCGGATATCAGACGCATATCTTTGGAAACAAACAACAACAATG TGGCCATTCCTCTCACTGGTGTCAAAGAAGCCTCTGCTTTGGATTTTGATGTCACAGACAACAGGATTTA CTGGACTGATATATCACTGAAGACTATTAGCAGAGCCTTTATGAATGGCAGTGCACTGGAACATGTGGTA GAGTTTGGCTTAGATTATCCAGAAGGCATGGCAGTGGACTGGCTTGGGAAGAACTTATACTGGGCAGACA CAGGAACAAATCGCATTGAGGTATCGAAGTTGGACGGACAGCACCGACAGGTTTTGGTATGGAAAGACCT TGACAGTCCTCGAGCTCTGGCACTGGATCCTGCTGAAGGGTTTATGTATTGGACTGAGTGGGGAGGCAAG CCTAAGATTGACAGGGCTGCTATGGATGGAAGTGAACGCACTACATTAGTTCCAAATGTAGGCCGAGCAA ATGGTCTCACCATCGACTATGCTAAAAGGCGGCTTTACTGGACAGACCTGGACACTAACCTAATAGAATC CTCAGATATGCTCGGACTCAACCGTGAAGTTATAGCAGATGACTTGCCTCATCCTTTTGGCTTAACTCAG TACCAAGATTACATCTACTGGACAGACTGGAGCCGACGCAGCATTGAACGTGCCAACAAAACCAGTGGCC AAAACCGCACCATCATCCAGGGCCATTTGGACTATGTGATGGACATCCTGGTCTTCCACTCTTCCCGGCA GGCAGGGTGGAATGAGTGTGCCTCCAGCAACGGGCACTGCTCCCACCTCTGCTTGGCTGTGCCCGTCGGA GGTTTTGTGTGTGGATGCCCTGCCCACTACTCCCTGAATGCTGACAACAGGACCTGCAGTGCTCCCACCA CCTTCCTGCTCTTCAGTCAGAAGAGCGCCATCAACCGCATGGTGATTGATGAACAACAGAGCCCTGACAT CATCCTTCCTATCCACAGCCTTCGGAACGTCCGGGCCATTGACTATGACCCTTTGGACAAGCAGCTCTAC TGGATTGACTCTCGACAAAACTCCATACGAAAGGCACATGAAGATGGTGGCCAGGGTTTTAATGTAGTTG CAAACTCAGTCGCAAATCAGAACCTTGAAATACAGCCCTATGATCTCAGCATTGATATTTATAGCCGTTA CATCTACTGGACCTGTGAAGCTACCAATGTCATTGATGTGACGAGATTAGATGGACGATCAGTTGGAGTG GTTCTAAAAGGCGAGCAAGACAGACCTCGAGCCATTGTGGTAAACCCCGAGAAAGGGTATATGTATTTTA CCAATCTTCAGGAAAGATCTCCTAAAATTGAACGGGCTGCATTGGATGGTACAGAACGAGAGGTCCTCTT TTTCAGTGGCTTAAGTAAACCAATTGCTTTGGCTCTTGATAGCAAGCTGGGCAAGCTCTTCTGGGCTGAC TCAGATCTCCGGCGAATTGAAAGCAGTGATCTCTCAGGTGCCAACAGGATCGTGCTAGAAGACTCTAATA TATTACAGCCTGTGGGCCTGACCGTGTTTGAAAACTGGCTCTATTGGATTGATAAACAGCAGCAGATGAT TGAAAAAATTGACATGACTGGTCGAGAAGGAAGAACCAAGGTCCAGGCTCGAATTGCTCAGCTGAGTGAC ATCCATGCAGTAAAGGAGCTGAACCTTCAGGAGTACAGACAGCACCCTTGTGCCCAGGATAATGGTGGCT GTTCACATATCTGCCTTGTAAAAGGAGATGGTACGACAAGATGCTCCTGCCCCATGCACTTAGTTCTGCT TCAGGATGAGCTGTCCTGTGGAGAGCCTCCAACGTGTTCTCCTCAGCAGTTTACCTGCTTCACTGGGGAC ATTGACTGCATCCCTGTGGCTTGGCGGTGTGATGGGTTCACTGAGTGCGAAGACCACAGCGATGAACTCA ATTGTCCCGTGTGCTCAGAGTCTCAGTTCCAGTGTGCCAGCGGGCAGTGCATTGATGGTGCCCTTCGATG CAATGGCGATGCGAACTGCCAGGACAAATCAGATGAGAAGAACTGTGAAGTGCTTTGTTTAATTGATCAG TTCCGCTGTGCCAATGGTCAGTGCGTTGGAAAGCACAAGAAATGTGACCACAGTGTGGACTGCAGTGACA GATCTGACGAGCTGGACTGTTATCCAACTGAGGAGCCAGCACCACAAGCCACCAACACAGTTGGTTCTGT TATTGGAGTAATTGTCACCATTTTTGTGTCTGGAACCATATACTTTATCTGCCAGAGGATGCTGTGTCCT CGTATGAAGGGAGACGGGGAGACCATGACTAACGACTATGTGGTTCACAGCCCGGCGTCTGTGCCCCTTG GTTATGTTCCTCACCCAAGCTCTCTCTCTGGATCTCTTCCAGGAATGTCTCGAGGCAAATCAATGATCAG TTCCCTCAGTATCATGGGGGGAAGCAGTGGGCCCCCCTATGATCGAGCGCACGTCACGGGAGCCTCCTCA AGCAGTTCTTCCAGTACCAAAGGCACTTACTTCCCTGCAATTTTGAACCCACCACCATCGCCTGCCACAG AAAGATCCCATTATACCATGGAATTTGGTTATTCTTCCAACAGTCCTTCCACACATAGGTCCTACAGCTA TAGGCCGTACAGCTACCGGCACTTTGCACCGCCCACCACACCCTGCAGCACTGATGTCTGTGACAGTGAC TATGCTCCTAGCCGGAGGATGACCTCGGTGGCAACAGCCAAGGGCTACACCAGTGACGTGAACTATGACT CAGAACCTGTGCCCCCACCGCCCACACCCCGAAGCCAGTACTTGTCAGCGGAGGAGAACTATGAAAGCTG CCCCCCTTCCCCATACACGGAGAGGAGTTACTCCCACCACCTCTACCCGCCACCACCCTCCCCCTGCACG GACTCCTCCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_008514 |
| Insert Size | 4842 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_008514.4, NP_032540.2 |
| RefSeq Size | 9368 bp |
| RefSeq ORF | 4842 bp |
| Locus ID | 16974 |
| UniProt ID | O88572 |
| Gene Summary | Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Required for posterior patterning of the epiblast during gastrulation (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG212053 | Lrp6 (tGFP-tagged) - Mouse low density lipoprotein receptor-related protein 6 (Lrp6) |
CNY 18,152.00 |
|
| MR212053 | Lrp6 (Myc-DDK-tagged) - Mouse low density lipoprotein receptor-related protein 6 (Lrp6) |
CNY 16,552.00 |
|
| MR212053L3 | Lenti ORF clone of Lrp6 (Myc-DDK-tagged) - Mouse low density lipoprotein receptor-related protein 6 (Lrp6) |
CNY 17,960.00 |
|
| MR212053L4 | Lenti ORF clone of Lrp6 (mGFP-tagged) - Mouse low density lipoprotein receptor-related protein 6 (Lrp6) |
CNY 17,960.00 |
Customer
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