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Pappa (NM_021362) Mouse Untagged Clone
CAT＃: MC224767
Pappa (untagged) - Mouse pregnancy-associated plasma protein A (Pappa), (10ug)
CNY 20,810.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 8430414N03Rik; IGFBP-4ase; PAG1; PAPP-A |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC224767 representing NM_021362
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCGGCTCTGGAGTTGGGTGCTGCGCCTGGGGCTGCTGAGCGCCGCGCTGGGCTGCGGGCTGGCCGAGC GCCCCCGCCGGGTCCGAAGAGACCCTCGGGCCGTGCGCCCCCCGCGCCCCGCCGCTGGACCGGCCACCTG CGCCACCCGGGCGGCCCGCGGTCGCCGCGCCTCGCCGCCGCCGCCTCCGGGCGGTGCCTGGGAAGCCGTG CGCGTCCCCCGGCGGCGGCAGCAGCGGGCGGCGAGGGGCGCCGAGGAGCCGAGCCCGCCTAGCCGGGCGC TCTATTTCAGCGGGCGAGGGGAGCAGCTGCGCCTCCGGGCCGACCTGGAGCTACCCCGCGACGCCTTTAC ACTGCAAGTGTGGCTGCGAGCCGAGGGTGGCCAGAAGTCTCCAGCAGTGATCACAGGGCTGTATGACAAA TGTTCTTATACCTCACGTGATCGAGGATGGGTCATGGGCATTCACACCACCAGTGATCAAGGCAACAGAG ATCCACGCTACTTTTTCTCCTTGAAGACAGACCGGGCCAGGAAAGTGACCACCATTGATGCCCATCGCAG CTACCTCCCAGGTCAGTGGGTACATCTAGCTGCTACCTATGATGGGCGGCTGATGAAGCTCTATATGAAT GGTGCCCAGGTGGCAACTTCGGCTGAGCAAGTAGGTGGCATATTCAGCCCACTGACCCAGAAGTGTAAAG TGCTCATGTTGGGGGGCAGTGCTCTGAATCACAACTTCCGGGGCCACATTGAACACTTCAGTCTATGGAA AGTAGCAAGAACCCAGCGAGAGATTGTATCCGACATGGAAACCCGTGGCCTCCACACCCCTCTACCTCAG CTCCTCCTCCAGGAGAACTGGGACAACGTGAAGCGCACTTGGTCCCCCATGAAGGATGGCAACAGCCCCC AGGTGGAATTCAGCAATGCCCACGGCTTCCTGTTGGACACTAATTTGGAGCCCCCTCTTTGTGGGCAGAC ACTGTGTGACAACACAGAAGTCATCTCCAGTTACAATCAGCTCCCAAGTTTTCGGCAGCCCAAGGTGGTC CGCTATCGTGTGGTCAACATCTATGATGATCACCATGAGAATCCAACGGTGAGCTGGCAACAGATTGACT TTCAGCACCAACAGCTGGCTGAGGCCTTTCAACACTACAACATCTCCTGGGAGCTGGAGGTACTGAATAT AAACAGTTCCTCTCTGCGTCACCGCCTCATCCTAGCCAACTGTGACATCAGCAAGATTGGGGATGAAAAA TGTGATCCAGAATGTAACCATACACTGACTGGTCATGATGGTGGAGATTGCCGCCAGCTGCGCTACCCTG CGTTCATGAAGAAGCAGCAGAATGGTGTGTGTGACATGGACTGTAACTACGAAAGGTTTAATTTTGATGG TGGAGAGTGCTGTGACCCAGACATCACTGATGTCACTAAGACATGCTTTGATCCTGACTCTCCACACAGA GCCTACTTGGATGTTAATGAGCTAAAGAACATTCTTAGACTGGACGGATCAACACATCTCAATATTTTCT TTGCAAACTCTTCAGAGGAGGAGTTGGCAGGAGTGGCAACTTGGCCATGGGACAAGGAAGCCCTAATGCA CTTGGGCGGTATTGTCTTGAACCCATCTTTCTATGGCATTCCCGGACACACCCACACCATGATTCATGAG ATTGGGCATAGCCTGGGCCTCTATCACATCTTCCGTGGCATCTCAGAAATCCAGTCCTGCAGTGATCCCT GCATGGAGACAGAGCCTTCATTTGAAACTGGAGACCTCTGCAATGATACCAACCCAGCCCCCAAACACAA GTTTTGTGGAGACCCTGGACCAGGGAATGACACTTGTGGCTTTCATGGCTTCTTCAACACTCCTTACAAC AACTTCATGAGCTACGCAGATGACGACTGTACAGACTCTTTCACGCCCAATCAAGTCTCCAGAATGCACT GTTACCTGGACCTCGTATACCAGAGCTGGCAGCCCTCCAGAAAGCCAGCACCTGTAGCTCTTGCGCCCCA GGTTGTGGGGCACACAATGGACTCTGTGATGCTAGAGTGGTTCCCACCCATCGATGGCCACTTCTTTGAA AGAGAATTGGGATCAGCATGTGACCTTTGCCTAGAAGGGAGAATCCTGGTGCAATATGCTTTCAATGCCT CCTCCCCCATGCCCTGTGGACCGTCAGGACACTGGAGTCCTCGGGAAGCAGAAGGTCACCCAGATGTTGA ACAGCCCTGTAAATCCAGTGTCCGAACCTGGAGTCCAAATTCAGCTGTCAACCCACACACAGTTCCTCCA GCCTGCCCTGAGCCACAAGGCTGCTACCTCGAGCTGGAATTTCGCTACCCTTTGGTCCCTGAGTCTCTGA CCATCTGGGTAACCTTTGTCTCCAGTGATTGGGACTCTAGTGGAGCTGTCAATGACATCAAACTCTTGAC TATCAGTGGAAAGAATATCTCTTTGGGTCCTCAGAATGTTTTCTGTGATATCCCACTTACCATCAGACTC CGGGATGTGGGTGAGGAGGTATATGGCATCCAAATCTATACTCTTGATGAGCACCTGGAGATTGATGCAG CAATGCTGACCTCCACTGTAGACAGTCCACTCTGCCTACAGTGTAAACCTCTGCAGTATAAAGTGCTTCG AGACCCACCTCTGCTAGAAGATGTAGCCTCATTACTCCACCTCAACAGAAGATTCATGGACACGGATCTG AAACTTGGCAGTGTGTACCAGTACCGGATTATCACCATTTCAGGAAATGAAGAGAGCGAGCCATCACCTG CTGCCATATACACCCACGGAAGTGGGTACTGTGGTGATGGCGTTATCCAAAAAGACCAAGGAGAAGAATG TGACGACATGAATAAGGTCAATGGGGATGGCTGCTCCCTTTTCTGCAAGCAAGAAGTTTCCTTCAACTGC ATTGATGAACCCAGCCGGTGCTATTTCCATGATGGGGATGGGATGTGTGAAGAGTTTGAACAAAAAACTA GCATTAAAGACTGTGGTGTCTACACGCCCCAGGGTTTCCTGGATCAGTGGGCATCCAATGCTTCAGTATC TCATCAAGACCAGCAGTGCCCAGGTTGGGTTGTCATTGGGCAGCCAGCGGCATCTCAGGTGTGTCGAACC AAGGTGATAGATCTCAGTGAAGGCATTTCCCAGCATGCTTGGTATCCTTGCACCATTACTTACCCATACT ACCATCTGCCTCAGACCACATTCTGGCTCCAGACATATTTCTCTCAGCCAATGGTTGCTGCAGCTGTAAT TATTCACCTGGTGACTGATGGGACATACTATGGGGACCAAAAGCAAGAGACCATCAGTGTGCAGTTGCTT GATACCAAAGATCAAAGCCATGATCTAGGCCTCCATGTCTTGAGCTGCAGAAACAATCCCCTGATTATCC CTGTGGTCCATGACCTCAGCCAGCCCTTCTACCACAGCCAGGCGGTACATGTGAGCTTCAGTTCGCCCCT GGTCGCCATCTCGGGGGTGGCCCTCCGCTCTTTCGACAACTTTGACCCCGTCACCCTGAGCAGCTGCCAG AGAGGAGAGACCTACAGCCCTGCTGAGCAGAGCTGTGTGCATTTTGCCTGTCAAGCTGCCGACTGCCCAG AACTGGCCGTGGGGAATGCTTCTCTCAACTGTTCCAGCAACCACCACTACCATGGTGCCCAGTGCACTGT GAGCTGCCAGACAGGTTATGTGCTGCAGATACAGCGGGACGATGAGCTAATCAAGAGCCAGGTAGGGCCA AGCATCACAGTGACATGTACCGAGGGCAAATGGAACAAGCAGGTGGCATGTGAGCCGGTGGACTGTGGTA TCCCAGATCACCATCACGTCTATGCTGCCTCCTTCTCCTGTCCAGAGGGTACCACCTTTGGTAGAAGATG TTCTTTTCAGTGTCGCCACCCTGCCCAGCTGAAAGGCAACAACAGCTTTCTGACCTGTATGGAAGATGGA CTGTGGTCCTTCCCAGAGGCCTTGTGTGAGCTCATGTGCCTCGCCCCACCCCCAGTTCCCAATGCGGACC TACAGACAGCCCGGTGTCGAGAGAACAAGCACAAGGTGGGCTCCTTCTGCAAGTACAAGTGTAAACCTGG ATACCACGTGCCTGGCTCATCTCGGAAGTCCAAGAAACGGGCTTTCAAGACTCAATGTACTCAAGATGGC AGCTGGCAAGAGGGAACTTGTGTGCCGGTGACTTGTGACCCACCTCCACCCAAATTCCATGGGCTCTATC AATGCACTAATGGCTTCCAGTTCAATAGTGAGTGCAGGATCAAGTGTGAAGACAGTGATGCCTCCCAGGG CCGTGGGAGCAATATCATTCACTGCCGGAAAGATGGCACTTGGAGTGGTTCCTTCCACGTCTGCCGAGAG ATGCAAGGCCAGTGCTCAGCCCCAAACCAACTCAACAGTAACCTCAAATTGCAGTGTCCTGATGGCTATG CAATAGGGTCAGAGTGTGCCATCTCGTGCCTGGACCATAACAGCGAGTCCATCATCCTTCCCGTTAACTT GACAGTGCGTGACATACCCCATTGGATGAACCCCACACGAGTACAGAGGATTGTCTGCACTGCTGGTCTC CAGTGGTATCCCCACCCTGCTCTGATCCACTGTGTCAAAGGCTGTGAGCCATTCATGGGAGACAACTACT GTGATGCCATCAACAATCGAGCCTTCTGCAACTATGATGGTGGGGACTGCTGCACCTCCACAGTAAAGAC CAAAAAGGTCACTCCCTTTCCTATGTCCTGTGACCTACAAAATGACTGCGCCTGTCGAGACCCTGAGGCC CAAGAACACAACCGGAAAGATCTTCGGGGATATAGCCATGGCTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_021362 |
| Insert Size | 4875 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_021362.1, NP_067337.1 |
| RefSeq Size | 11027 bp |
| RefSeq ORF | 4875 bp |
| Locus ID | 18491 |
| UniProt ID | Q8R4K8 |
| Gene Summary | Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF. Isoform 2 cleaves IGFBP-4 very slowly compared to PAPP-A, but its ability to cleave IGFBP-5 is unaffected.[UniProtKB/Swiss-Prot Function] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG227070 | Pappa (tGFP-tagged) - Mouse pregnancy-associated plasma protein A (Pappa), (10ug) |
CNY 13,300.00 |
|
| MR227070 | Pappa (Myc-DDK-tagged) - Mouse pregnancy-associated plasma protein A (Pappa) |
CNY 11,112.00 |
|
| MR227070L3 | Lenti ORF clone of Pappa (Myc-DDK-tagged) - Mouse pregnancy-associated plasma protein A (Pappa) |
CNY 13,970.00 |
|
| MR227070L4 | Lenti ORF clone of Pappa (mGFP-tagged) - Mouse pregnancy-associated plasma protein A (Pappa) |
CNY 13,970.00 |
