Acacb (NM_133904) Mouse Untagged Clone

Specifications

Product Data
Type	Mouse Untagged Clone
Tag	Tag Free
Synonyms	Acc2; Accb; AI597064; AW743042
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >MC225320 representing NM_133904 Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGTCTTGCTTCTCTTTCTGACTTGCCTGGTTTTCTCCTGCCTGACCTTTTCCTGGCTAAAAATCTGGG GGAAGATGACAGACTCGAAGCCGCTCACCAACAGTAAGGTGGAAGCCAATCTCCTTTCAAGCGAGGAGTC CCTTTCAGCCTCAGAGCTGTCAGGGGAACAGCTGCAGGAACATGGCGACCACAGCTGTCTGTCCTACAGA GGTCCCAGAGACGCCAGTCAGCAGAGGAACTCCCTGCCAAGCTCATGCCAGAGGCCTCCGAGGAACCCAC TGTCTTCCAATGACACCTGGCCCTCCCCAGAACTCCAAACCAACTGGACAGCCGCCCCGGGCCCAGAGGT TCCAGATGCTAATGGGTTGTCCTTCCCAGCCAGGCCCCCGAGCCAGAGGACAGTATCCCCCTCCAGAGAG GACAGGAAGCAGGCACACATCAAGAGACAGCTGATGACCAGCTTTATCCTGGGCTCCCTGGATGACAACT CCTCTGATGAGGACCCTAGTGCCGGCTCCTTCCAGAACTCCTCCCGGAAGAGCAGCAGGGCTAGCCTGGG CACTCTGTCCCAGGAGGCTGCATTGAACACAAGTGATCCTGAATCTCACGCGCCTACTATGAGGCCCAGC ATGTCTGGACTCCATCTGGTGAAGAGAGGCCGAGAACACAAGAAACTGGACCTGCACAGAGATTTCACCG TCGCGTCCCCAGCCGAGTTTGTCACTCGGTTTGGAGGCAACAGGGTCATAGAGAAGGTGCTCATCGCCAA CAATGGCATCGCTGCGGTCAAGTGTATGCGCTCCATCCGCCGCTGGGCCTACGAGATGTTCCGTAATGAA CGTGCCATCCGGTTCGTGGTCATGGTGACGCCCGAGGATCTGAAGGCCAACGCAGAGTACATCAAGATGG CCGATCAGTACGTCCCTGTCCCAGGAGGACCCAATAACAACAACTATGCCAATGTTGAGCTGATCATAGA CATTGCCAAGAGAATCCCTGTACAGGCCGTGTGGGCTGGCTGGGGCCACGCTTCGGAAAACCCCAAACTT CCAGAGCTGCTGTGTAAACACGAGATTGCTTTCCTAGGTCCCCCCAGTGAGGCCATGTGGGCCCTGGGAG ACAAGATCGCCTCCACCATCGTAGCGCAGACACTGCAAATCCCAACCTTACCCTGGAGTGGAAGCGGTCT CACAGTGGAGTGGACGGAGGACAGCCGGCACCAGGGCAAATGCATCAGTGTCCCCGAAGACGTTTACGAG CAGGGCTGTGTGAAGGATGTGGACGAAGGCTTGCAGGCAGCAGAAAAAATAGGATTTCCTTTGATGATCA AAGCCTCCGAAGGCGGAGGCGGGAAAGGTATCCGCAAGGCTGAGAGTGCAGAGGACTTCCCGATGCTTTT CCGACAAGTGCAGAGTGAGATTCCGGGCTCGCCGATCTTTCTAATGAAGCTGGCCCAGAACGCACGGCAC CTGGAGGTCCAGGTCTTGGCAGATCAGTATGGAAACGCGGTGTCACTGTTCGGACGGGACTGTTCCATTC AGAGGCGGCACCAGAAGATCATTGAGGAGGCTCCGGCCACCATCGCCGCGCCTGCCGTGTTTGAGTTCAT GGAACAGTGTGCTGTCCTCCTGGCCAAGATGGTGGGTTATGTGAGCGCGGGGACTGTGGAGTACTTATAC AGCCAGGATGGCAGCTTCCACTTCCTGGAGCTGAACCCACGCCTGCAGGTGGAGCATCCGTGCACTGAAA TGATCGCAGATGTCAACCTGCCTGCTGCGCAGTTGCAGATCGCCATGGGCGTGCCCCTGCACCGACTGAA GGACATACGGCTTCTGTACGGAGAGTCCCCCTGGGGAGTGACCCCCATTCCTTTTGAAACCCCCTTGAGC CCTCCCATTGCCCGAGGCCACGTCATTGCAGCCAGGATCACCAGCGAAAACCCAGATGAGGGCTTTAAGC CAAGCTCGGGGACAGTGCAGGAGCTGAACTTCCGCAGCAACAAGAACGTGTGGGGTTACTTCAGCGTGGC CGCTGCTGGGGGCTTGCACGAGTTCGCCGATTCCCAGTTTGGGCACTGCTTCTCCTGGGGCGAGAACCGT GAAGAGGCCATTTCGAACATGGTAGTGGCTTTGAAGGAACTGTCCATCCGGGGTGACTTCCGGACCACTG TGGAGTATCTCGTTAACCTTCTGGAGACCGAGAGCTTCCAGAACAACGATATCGACACGGGGTGGCTGGA CCACCTCATCGCTCAGCGGGTGCAGGCAGAGAAGCCGGACATCATGCTTGGGGTGGTGTGTGGGGCCTTG AATGTGGCAGACGCGATGTTCAGAACCTGCATGACGGAATTCTTGCACTCCCTGGAAAGGGGTCAGGTCC TCCCTGCTGATTCTCTGCTGAACATTGTGGACGTTGAATTGATTTACGGCGGCATCAAGTATGCTCTCAA GGTAGCCCGACAGTCCCTGACTATGTTTGTCCTCATCATGAACGGCTGCCACATCGAGATCGATGCCCAC CGGCTGAACGATGGGGGGCTGCTCCTGTCCTACAATGGCAGCAGTTACACTACGTACATGAAGGAAGAGG TTGACAGTTACCGGATCACTATCGGCAATAAGACTTGCGTGTTTGAAAAGGAAAACGACCCCACTGTCCT GAGATCCCCCTCGGCTGGGAAGCTGATGCAGTATACGGTGGAGGACGGAGACCACGTGGAAGCTGGGAGC AGCTACGCGGAGATGGAGGTGATGAAGATGATCATGACCCTGAACGTGCAGGAGAGCGGCCGGGTGAAGT ACATCAAGCGGCCAGGGGTTATACTGGAGGCTGGCTGCGTGGTGGCGAGGCTAGAACTCGATGACCCTTC AAAAGTGCACGCGGCCCAGCCGTTTACTGGGGAGCTCCCTGCCCAGCAGACTCTGCCCATCCTCGGGGAG AAGCTACACCAAGTGTTCCACGGCGTCTTGGAAAATCTGACCAATGTCATGAGTGGCTACTGCCTGCCCG AGCCCTTCTTCAGCATGAAGCTGAAGGACTGGGTCCAGAAGCTCATGATGACGCTCCGGCATCCCTCCCT ACCTCTGCTGGAGCTACAGGAGATCATGACCAGTGTGGCCGGCCGCATCCCCGCCCCGGTGGAGAAGGCA GTCCGCAGGGTGATGGCCCAGTACGCCAGTAACATCACCTCCGTGCTATGCCAGTTCCCCAGCCAGCAGA TAGCCACCATCCTGGACTGCCATGCCGCCACCCTGCAGCGTAAGGCGGACCGAGAGGTCTTCTTCATGAA CACACAGAGCATCGTGCAGCTGGTCCAGAGATACCGCAGCGGGACCCGTGGCTACATGAAGGCTGTGGTG CTGGACCTCCTGAGGAAATATCTAAACGTGGAGCACCATTTTCAGCAAGCCCACTATGACAAGTGTGTGA TCAACCTGAGGGAGCAGTTCAAGCCGGACATGACCCAGGTGCTGGACTGCATCTTCTCACACTCCCAGGT GGCCAAGAAGAACCAGCTGGTGACCATGCTGATAGATGAGCTGTGCGGCCCAGACCCCACCCTGTCAGAC GAGCTGACCTCCATCCTCTGTGAGCTCACGCAGCTGAGCAGAAGCGAGCACTGCAAGGTTGCCCTCAGAG CCAGACAGGTCCTGATCGCCTCCCACCTCCCCTCCTACGAGCTGCGGCACAACCAGGTGGAGTCCATCTT CCTGTCCGCCATCGACATGTACGGCCACCAGTTCTGCCCAGAAAATCTCAAGAAACTAATACTTTCAGAA ACGACCATATTCGACGTCCTGCCCACTTTCTTCTATCACGAGAACAAGGTTGTCTGTATGGCGTCCCTGG AGGTTTACGTGCGGAGAGGCTACATCGCCTACGAGCTAAACAGCCTGCAGCACCGGGAGCTCCCAGATGG CACCTGTGTGGTGGAGTTCCAGTTCATGCTGCCCTCTTCCCACCCCAACCGGATGGCCGTGCCCATCAGT GTCTCCAACCCCGACCTGCTGAGGCACAGCACAGAACTCTTCATGGACAGTGGCTTCTCCCCACTGTGCC AGCGGATGGGGGCCATGGTGGCCTTCAGGAGATTTGAAGAATTCACCAGGAACTTTGATGAAGTCATCTC CTGCTTTGCCAACGTGCAGACAGACACTCTTCTCTTCAGTAAGGCGTGCACTTCCCTGTACTCAGAGGAA GACAGCAAGAGCCTCCGAGAGGAACCCATCCACATCCTGAATGTGGCCATCCAGTGTGCCGACCACATGG AGGACGAGGCGCTGGTGCCAGTCTTCCGTGCCTTTGTACAGTCCAAGAAGCACATCCTTGTGGATTACGG ACTCCGAAGAATCACATTCCTTGTTGCCCAAGAGAGAGAATTCCCCAAGTTCTTCACGTTCAGAGCGAGG GATGAGTTTGCAGAAGACCGGATTTATCGCCACTTGGAGCCTGCCCTGGCCTTCCAGCTGGAGCTGAGCC GGATGCGCAACTTTGACCTGACCGCTGTGCCCTGTGCCAACCACAAGATGCATCTTTACCTGGGAGCCGC TAAGGTGAAGGAAGGGTTGGAGGTGACCGACCACAGGTTCTTTATCCGAGCCATTATCCGGCACTCAGAC CTGATCACCAAGGAAGCCTCCTTCGAGTACCTGCAGAACGAAGGTGAGCGGCTGCTGCTGGAAGCCATGG ACGAGCTGGAGGTGGCGTTCAACAACACCAGTGTGCGCACTGACTGCAACCACATCTTCCTCAACTTTGT GCCCACAGTCATCATGGACCCGCTCAAGATCGAGGAGTCGGTGCGTGACATGGTCATGCGCTATGGCAGC CGTCTGTGGAAGCTCCGAGTGCTGCAGGCCGAGGTTAAGATCAACATCCGTCAGACAACCTCAGATAGTG CCATCCCCATCCGCCTCTTCATCACCAACGAGTCTGGCTACTACCTGGACATCAGCCTCTATAGAGAAGT GACGGACTCCAGATCCGGAAATATCATGTTTCATTCCTTTGGCAACAAGCAAGGTAGCCTGCATGGGATG CTGATCAATACACCCTATGTCACCAAGGACCTGCTCCAGGCTAAGCGATTCCAGGCACAGTCCCTCGGGA CCACCTATGTGTACGACTTCCCAGAGATGTTCAGGCAGGCTCTCTTTAAACTGTGGGGCTCCCCAGAGAA GTACCCCAAAGATATCCTGACATACACAGAGCTGGTGTTGGACTCTCAAGGTCAGCTGGTGGAGATGAAC CGGCTTCCTGGTTGTAACGAGGTGGGCATGGTGGCCTTCAAAATGAGGTTCAAGACCCCGGAGTATCCAG AAGGCCGGGACGCCGTTGTCATCGGCAATGACATCACCTTCCAAATCGGCTCTTTCGGCATAGGGGAGGA CTTCCTGTACCTGCGAGCGTCTGAGATGGCCCGGACAGAGGGCATCCCCCAAATCTACCTGGCAGCTAAC AGCGGGGCCCGTATGGGCCTGGCTGAGGAGATCAAACAGATATTCCAAGTGGCTTGGGTGGACCCAGAGG ATCCCCACAAAGGATTTAGATACCTGTACCTGACGCCCCAAGACTACACCCAGATCAGTTCCCAGAACTC AGTGCACTGCAAGCACATCGAAGATGAAGGCGAATCCAGATACGTCATCGTGGATGTCATCGGGAAGGAT GCCAACCTGGGTGTGGAGAACCTGAGGGGCTCGGGCATGATTGCAGGAGAAGCTTCCCTGGCTTATGAGA AAACGGTCACCATCAGCATGGTGACCTGCCGCGCCCTTGGAATCGGGGCTTACCTGGTGAGGCTTGGCCA GCGGGTGATCCAGGTGGAAAACTCCCACATCATCCTCACCGGAGCCGGTGCTCTCAACAAGGTCCTGGGA AGAGAGGTCTACACGTCCAACAACCAGCTAGGTGGCGTGCAGATCATGCATACCAACGGGGTCTCCCACG TCACCGTGCCAGATGACTTCGAGGGGGTCTGCACCATTCTGGAATGGCTGTCATTTATACCGAAGGACAA TCGCAGCCCGGTCCCCATCACCACTCCTTCTGACCCCATCGACAGGGAAATTGAATTCACCCCAACCAAA GCTCCCTACGACCCCAGGTGGATGCTTGCAGGCAGGCCTCACCCAACTCTGAAGGGGACCTGGCAGAGTG GATTCTTCGACCATGGCAGTTTCAAGGAAATCATGGCACCCTGGGCCCAGACTGTGGTGACGGGACGAGC AAGGCTGGGGGGCATCCCTGTGGGAGTGATTGCTGTGGAGACTCGGACTGTGGAGGTGGCTGTCCCCGCT GACCCTGCCAACTTGGATTCTGAGGCCAAGATCATCCAGCAGGCGGGCCAGGTGTGGTTCCCGGACTCGG CCTACAAGACGGCGCAGGTCATCAGGGACTTCAACAAGGAGCGCCTGCCTCTCATGATCTTCGCCAACTG GAGGGGCTTCTCCGGAGGCATGAAGGACATGTATGAGCAGATGCTGAAGTTTGGCGCCTACATCGTGGAT GGTCTCCGCCTGTACGAGCAGCCCATTCTCATCTACATCCCTCCCTGTGCGGAGCTCCGTGGGGGCTCCT GGGTTGTCCTGGACTCCACCATCAACCCCCTGTGCATAGAGATGTATGCAGACAAAGAGAGCAGGGGGGG TGTTCTGGAGCCGGAGGGCACGGTGGAGATTAAGTTCCGGAAGAAAGATCTGGTGAAAACCATAAGGAGG ATAGACCCAGTGTGTAAGAAGCTCGTGGGACAGCTGGGGAAAGCCCAGCTTCCCGACAAGGACCGGAAGG AGCTGGAGGGCCAGCTGAAGGCCCGGGAGGAACTGCTGCTTCCCATCTACCACCAGGTGGCAGTGCAGTT CGCAGACCTGCACGACACCCCGGGCCACATGCTGGAGAAAGGAATCATTTCTGATGTGCTGGAATGGAAG ACTGCCCGCACCTTCTTCTACTGGAGGCTGCGCCGGCTGCTGCTGGAGGCCCAGGTGAAGCAGGAGATAC TCCGAGCCAGCCCCGAGCTGAACCACGAGCACACACAGTCCATGCTGCGACGCTGGTTCGTGGAGACTGA GGGCGCTGTCAAGGCCTACCTGTGGGACAGCAACCAGGTGGTGGTCCAGTGGCTGGAACAGCACTGGTCA GCCAAGGACGGCTTGCGCTCCACCATCCGTGAAAACATCAATTATCTGAAGCGGGACTCTGTCCTCAAGA CCATCCAAAGTCTGGTCCAAGAACATCCAGAGGTCATCATGGACTGCGTGGCCTACCTGAGCCAGCACCT CACGCCAGCCGAGCGGATACAGGTGGCTCAGCTGCTGTCTACCACGGAGAGCCCAGCTTCCTCCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites	SgfI-MluI
ACCN	NM_133904
Insert Size	7347 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_133904.2, NP_598665.2
RefSeq Size	8497 bp
RefSeq ORF	7347 bp
Locus ID	100705
UniProt ID	E9Q4Z2
Gene Summary	Catalyzes the ATP-dependent carboxylation of acetyl-CoA to malonyl-CoA (By similarity). Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase (By similarity). Involved in inhibition of fatty acid and glucose oxidation and enhancement of fat storage (PubMed:11283375, PubMed:12920182, PubMed:15677334, PubMed:18487439, PubMed:22362781). May play a role in regulation of mitochondrial fatty acid oxidation through malonyl-CoA-dependent inhibition of carnitine palmitoyltransferase 1 (PubMed:10677481).[UniProtKB/Swiss-Prot Function]

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