Azi2 (NM_001286507) Mouse Untagged Clone

Specifications

Product Data
Type	Mouse Untagged Clone
Tag	Tag Free
Synonyms	AA410145; AZ2
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >MC225905 representing NM_001286507 Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGATGAGGAATTTAAACCCACCCTCATCCAGCTGGGAGGTGGAGAAGCTAAGCTGTGACTTGAAGATCC ATGGTTTGGAGCAAGAGCTGGGACTACTGAGGAAGGAGTGCAGTGACCTCAGGACAGAGCTGCAGAAGGC CAGACAGACGGGTCCACCTCAGGAAGACATTCTGCAGGGCAGAGATGTCATCAGGCCGAGCTTGTCGAGA GAAGAGCATGTTCCACACCAGGGTCTTCACCACAGTGATAATATGCAACATGCATACTGGGAACTGAAGA GGGAGATGTCTAACTTACACCTGGTGACTCAAGTGCAAGCAGAACTACTAAGAAAACTGAAAACCTCAGC TGCAGTCAAGAAAGGTTGTCAACTCATCCACACCGAGAATCCACTAAAATCCAAACAGCTGGGCACACCT GGGAGCCATGTTTCTTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites	SgfI-MluI
ACCN	NM_001286507
Insert Size	438 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	Clone contains native stop codon, and expresses the complete ORF without any c-terminal tag.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001286507.1, NP_001273436.1
RefSeq Size	1911 bp
RefSeq ORF	438 bp
Locus ID	27215
UniProt ID	Q9QYP6
Gene Summary	Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (3) differs in both UTR's and the coding region but maintains the reading frame, compared to variant 1. This results in a protein that has shorter N-terminus and distinct C-terminus, compared to isoform a.

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