Dach2 (NM_001289733) Mouse Untagged Clone
CAT#: MC227738
Dach2 (untagged) - Mouse dachshund 2 (Drosophila) (Dach2), transcript variant 4
CNY 4,280.00
货期*
3周
规格
Product images
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经常一起买 (4)
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | 9430028N04Rik |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC227738 representing NM_001289733
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACAAGGAAACAAGCTGTTAACAGTTCAAGGCCTGGCAGGCCCCCTAAGCGTTCTTTGGGAGTATTGC AAGATAATGCCCGACTTCTGCCCCATGCAGTCCCAGGCCTCTTATCACCAGGACTGATCACTCCAACAGG TATCACAGCTGCAGCGATGGCTGAGGCCATGAAGCTCCAGAAGATGAAGCTTATGGCAATGAATACTCTT CAGGGTAATGGAAGCCAAAATGGGACTGAGTCAGAGCCAGATGACCTTAATTCTACGACAGGTGGAAGTG AATCCTCCTGGGATAAAGATAAGATACAATCTCCACTTGCTGCTTCTGGACCTCAACATGGAATTGCTCA TGCAGCACTTGCTGGTCAGCCAGGCCTTGGAGGTGCTCCGACCCTTAATCCACTTCAGCAGAATCACCTG CTAAGCAATCGTCTGGATCTCCCATTTATGATGATGCCTCATCCCCTACTTCCAGTCAGCTTACCTCCTG CATCAGTTGCCATGGCAATGAATCAGATGAATCATCTCAATACTATTGCCAACATGGCTGCTGCAGCCCA GATTCACAGTCCACTCTCCAGAGCTGGTGCCTCTGTTATAAAGGAACGGATCCCAGAGAGTCCTTCTCCT GCTCCCTCTCTGGAAGAGAGTCATCGTCCTGGGAGCCAGACCTCCTCCCACCCAAGCAGCAGTGTGTCCA GCTCTCCCTCGCAGATGGATCATCATTCAGAGAGAATGGTTATGATGCCCAACAATCGAGAAGAGCTTAT TGTTGACCAAGATAATGGACAAAGCATAAAAAAATTCCAGAGGGATAATAAAGAAGAAGTACCAGCTCAA ATCCCAGTCATGAAGTCACCCTTGGATAAGATCCAGTTGGCTCCTGGACAGGCATTGCATCCTGGATTCC CTGGACCATTCATTTTTGCAGATAGTCTATCTTCTGTGGAGACTCTGTTGACCAACATTCAGGGTCTACT GAAAGTGGCTTTGGATAATGCTCGTATCCAGGAGAAGCAGATTCAGCAGGAAAAGAAGGAACTGCGAATA GAGCTCTTCAGAGAAAGAGAAATTAGAGAAAACCTGGAGCGACAACTTGCAGTTGAGCTTCAAAGCAGAA GTACAATGCAAAAGCGTCTGAAAAAAGAGAAAAAGGCTAAGAGAAAACTTCAGGAAGCCTTGGAATTTGA ATCAAAGCGCCGCGAGCAAGTGGAGCAAGCACTTAAACAAGCTACATCTGGTGACAGTGGACTGAGAATG TTAAAAGATTCTGGAATTCCAGATATTGAAATAGAAAACAGTGGAACGCCGCATGACAGTGCTGCTATGC AAGCCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_001289733 |
Insert Size | 1338 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | Clone contains native stop codon, and expresses the complete ORF without any c-terminal tag. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001289733.1, NP_001276662.1 |
RefSeq Size | 5708 bp |
RefSeq ORF | 1338 bp |
Locus ID | 93837 |
UniProt ID | Q925Q8 |
Gene Summary | Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator for SIX1 and SIX6. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. Is recruited with SIX6 to the p27Kip1 promoter in embryonal retina. SIX6 corepression seems also to involve NCOR1, TBL1, HDAC1 and HDAC3. May be involved together with PAX3, SIX1, and EYA2 in regulation of myogenesis. In the developing somite, expression of DACH2 and PAX3 is regulated by the overlying ectoderm, and DACH2 and PAX3 positively regulate each other's expression. Probably binds to DNA via its DACHbox-N domain.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (4) has multiple differences, compared to variant 1. These differences result in a distinct 5' UTR and cause translation initiation at an alternate start codon, compared to variant 1. The encoded protein (isoform 4) is shorter and has a distinct N-terminus, compared to isoform 1. |
Documents
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MR229949 | Dach2 (myc-DDK-tagged) - Mouse dachshund 2 (Drosophila) (Dach2), transcript variant 4 |
CNY 4,470.00 |
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