Traf2 (NM_001290413) Mouse Untagged Clone

CAT#: MC228093

Traf2 (untagged) - Mouse TNF receptor-associated factor 2 (Traf2), transcript variant 1



  "NM_001290413" in other vectors (1)

CNY 4,940.00


货期*
4周

规格
    • 10 ug

Product images

经常一起买 (3)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Synonyms AI325259
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MC228093 representing NM_001290413
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGCTGCAGCCAGTGTGACTTCCCCTGGCTCCCTAGAACTGCTACAGCCTGGCTTCTCCAAGACCCTCC
TGGGGACCAGGTTAGAAGCCAAGTACCTCTGTTCAGCCTGCAAAAACATCCTGCGGAGGCCTTTCCAGGC
CCAGTGTGGGCACCGCTACTGCTCCTTCTGCCTGACCAGCATCCTCAGGTGTGCATCCATTCTCTCCAGC
TCTGGGCCCCAGAACTGTGCTGCCTGTGTCTATGAAGGCCTGTATGAAGAAGGCATTTCTATTTTAGAGA
GTAGTTCGGCCTTTCCAGATAACGCTGCCCGCAGAGAGGTGGAGAGCCTGCCAGCTGTCTGTCCCAATGA
TGGATGCACTTGGAAGGGGACCTTGAAAGAATACGAGAGCTGCCACGAAGGACTTTGCCCATTCCTGCTG
ACGGAGTGTCCTGCATGTAAAGGCCTGGTCCGCCTCAGCGAGAAGGAGCACCACACTGAGCAGGAATGCC
CCAAAAGGAGCCTGAGCTGCCAGCACTGCAGAGCACCCTGTAGCCACGTGGACCTGGAGGTACACTATGA
GGTCTGCCCCAAGTTTCCCTTAACCTGTGATGGCTGTGGCAAGAAGAAGATCCCTCGGGAGACGTTTCAG
GACCATGTTAGAGCATGCAGCAAATGCCGGGTTCTCTGCAGATTCCACACCGTTGGCTGTTCAGAGATGG
TGGAGACTGAGAACCTGCAGGATCATGAGCTGCAGCGGCTACGGGAACACCTAGCCCTACTGCTGAGCTC
ATTCTTGGAGGCCCAAGCCTCTCCAGGAACCTTGAACCAGGTGGGGCCAGAGCTACTCCAGCGGTGCCAG
ATTTTGGAGCAGAAGATAGCAACCTTTGAGAACATTGTCTGCGTCTTGAACCGTGAAGTAGAGAGGGTAG
CAGTGACTGCAGAGGCTTGTAGCCGGCAGCACCGGCTAGACCAGGACAAGATTGAGGCCCTGAGTAACAA
GGTGCAACAGCTGGAGAGGAGCATCGGCCTCAAGGACCTGGCCATGGCTGACCTGGAGCAGAAGGTCTCC
GAGTTGGAAGTATCCACCTATGATGGGGTCTTCATCTGGAAGATCTCTGACTTCACCAGAAAGCGTCAGG
AAGCCGTAGCTGGCCGGACACCAGCTATCTTCTCCCCAGCCTTCTACACAAGCAGATATGGCTACAAGAT
GTGTCTACGAGTCTACTTGAATGGCGACGGCACTGGGCGGGGAACTCATCTGTCTCTCTTCTTCGTGGTG
ATGAAAGGCCCCAATGATGCTCTGTTGCAGTGGCCTTTTAATCAGAAGGTAACATTGATGTTGCTGGACC
ATAACAACCGGGAGCATGTGATCGACGCATTCAGGCCCGATGTAACCTCGTCCTCCTTCCAGAGGCCTGT
CAGTGACATGAACATCGCCAGTGGCTGCCCCCTCTTCTGCCCTGTGTCCAAGATGGAGGCCAAGAATTCC
TATGTGCGGGATGATGCGATCTTCATCAAAGCTATTGTGGACCTAACAGGACTCTAG


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI     
ACCN NM_001290413
Insert Size 1527 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation Clone contains native stop codon, and expresses the complete ORF without any c-terminal tag.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_001290413.1, NP_001277342.1
RefSeq Size 3065 bp
RefSeq ORF 1527 bp
Locus ID 22030
UniProt ID P39429
Gene Summary Regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis. Required for normal antibody isotype switching from IgM to IgG. Has E3 ubiquitin-protein ligase activity and promotes 'Lys-63'-linked ubiquitination of target proteins, such as BIRC3, RIPK1 and TICAM1. Is an essential constituent of several E3 ubiquitin-protein ligase complexes, where it promotes the ubiquitination of target proteins by bringing them into contact with other E3 ubiquitin ligases. Regulates BIRC2 and BIRC3 protein levels by inhibiting their autoubiquitination and subsequent degradation; this does not depend on the TRAF2 RING-type zinc finger domain. Isoform 2 does not seem to mediate activation of NF-kappa-B but inhibits isoform 1 activity. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR. In complex with BIRC2 or BIRC3, promotes ubiquitination of IKBKE.[UniProtKB/Swiss-Prot Function]
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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