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Kat2b (NM_001190846) Mouse Tagged ORF Clone
CAT＃: MG225908
- TrueORF®
Kat2b (tGFP-tagged) - Mouse K(lysine) acetyltransferase 2B (Kat2b) transcript variant 2, (10ug)
ORF Plasmid: DDK
"NM_001190846" in other vectors (3)
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CNY 6,370.00
Product images
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | A930006P13Rik; AI461839; AW536563; p/CAF; Pcaf |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MG225908 representing NM_001190846
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAGTCCTGAAATGGCAGAGGAGTCCTGTAAATGCAATGGCTGGAAGAACCCTAACCCCTCTCCTACTC CACCAAGAGGAGACCTCCAGCAGATAATTGTCAGTTTGACAGAATCCTGTCGAAGCTGTAGCCATGCCCT TGCTGCTCACGTTTCTCACTTGGAGAATGTGTCAGAGGAAGAGATGGACAGACTCCTGGGAATTGTGTTG GATGTGGAGTACCTCTTCACCTGCGTCCACAAAGAAGAAGATGCAGATACCAAACAAGTGTACTTCTACC TATTCAAGCTCTTGAGAAAGTCAATTTTACAAAGAGGAAAACCTGTGGTTGAAGGCTCCTTGGAGAAGAA GCCGCCATTTGAGAAGCCCAGTATTGAACAGGGTGTGAACAACTTCGTGCAGTACAAGTTTAGTCACTTG CCATCGAAAGAGAGGCAGACAACGATCGAGCTGGCCAAGATGTTTCTGAACCGCATCAACTACTGGCATC TGGAGGCTCCATCTCAGCGGAGACTACGGTCTCCCAATGATGACATCTCTGGATACAAGGAAAACTACAC AAGGTGGTTGTGCTACTGCAATGTACCGCAGTTCTGTGACAGCTTACCTCGGTACGAAACCACAAAGGTG TTTGGGAGAACATTGCTTCGCTCGGTCTTCACCATCATGAGACGACAGCTCTTGGAACAAGCCAGACAGG AAAAAGACAAACTGCCTCTTGAGAAACGCACGCTTATCCTCACACATTTCCCAAAGTTTCTGTCCATGTT GGAAGAAGAAGTGTATAGTCAAAATTCTCCTATCTGGGATCAGGATTTTCTCTCAGCCTCTTCCAGAACC AGCCCGCTAGGAATCCAAACAGTAATCAGTCCTCCTGTTACTGGGACAGCATTGTTCAGTTCAAATTCCA CTTCCCATGAGCAGATCAATGGAGGGAGAACAAGTCCTGGATGCAGAGGCTCTTCTGGGCTTGAAGCAAA CCCGGGAGAAAAGAGGAAAATGAACAACTCTCATGCTCCCGAGGAGGCCAAGAGATCTCGAGTGATGGGG GATATTCCCGTGGAATTGATCAATGAGGTCATGTCTACCATCACAGACCCTGCAGGGATGCTTGGACCAG AGACCAATTTTCTGTCAGCCCATTCGGCCAGAGATGAGGCGGCACGGCTGGAAGAACGCAGGGGTGTCAT TGAATTCCACGTGGTGGGCAACTCCCTGAACCAGAAACCAAACAAGAAGATCCTGATGTGGCTCGTGGGC CTCCAGAATGTGTTTTCCCACCAGCTGCCCAGAATGCCCAAAGAGTACATCACACGGCTCGTCTTTGACC CGAAACACAAAACCCTTGCTTTAATTAAAGATGGCCGTGTCATTGGTGGTATCTGTTTCCGGATGTTTCC ATCCCAGGGATTCACAGAGATTGTTTTCTGTGCAGTAACCTCAAATGAACAAGTCAAGGGCTATGGAACC CACCTGATGAACCATCTCAAAGAATACCACATAAAGCACGAGATCCTCAACTTCCTCACATATGCAGATG AGTATGCCATCGGCTATTTCAAGAAGCAGGGTTTCTCCAAAGAAATCAAAATACCTAAAACCAAATATGT TGGCTACATCAAGGATTATGAAGGGGCCACTTTGATGGGATGTGAGCTGAACCCTCAGATCCCATACACA GAGTTCTCTGTCATCATTAAAAAGCAGAAGGAGATCATTAAAAAGCTGATAGAAAGAAAACAAGCCCAGA TTCGAAAAGTCTACCCTGGACTTTCGTGTTTCAAAGATGGAGTTCGGCAGATTCCTATAGAAAGCATTCC TGGAATCAGAGAGACAGGCTGGAAACCAAGTGGAAAAGAGAAAAGTAAAGAGCCCAAAGACCCTGAGCAG CTTTACAGCACCCTCAAGAACATCCTGCAGCAGGTGAAGAACCATCCAAATGCTTGGCCTTTCATGGAAC CAGTGAAGAGAACAGAAGCTCCGGGATATTATGAAGTTATAAGGTTCCCCATGGATCTGAAAACCATGAG TGAACGCCTCAGGAACAGGTACTATGTGTCTAAGAAGTTATTCATGGCGGACTTGCAACGAGTGTTCACC AACTGCAAGGAGTACAACCCTCCCGAGAGCGAGTACTACAAATGCGCCAGCATCCTGGAGAAGTTCTTCT TCAGTAAAATTAAGGAAGCAGGGTTGATTGACAAG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >MG225908 representing NM_001190846
Red=Cloning site Green=Tags(s) MSPEMAEESCKCNGWKNPNPSPTPPRGDLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMDRLLGIVL DVEYLFTCVHKEEDADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHL PSKERQTTIELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPRYETTKV FGRTLLRSVFTIMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFLSASSRT SPLGIQTVISPPVTGTALFSSNSTSHEQINGGRTSPGCRGSSGLEANPGEKRKMNNSHAPEEAKRSRVMG DIPVELINEVMSTITDPAGMLGPETNFLSAHSARDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVG LQNVFSHQLPRMPKEYITRLVFDPKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGT HLMNHLKEYHIKHEILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPQIPYT EFSVIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPKDPEQ LYSTLKNILQQVKNHPNAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLRNRYYVSKKLFMADLQRVFT NCKEYNPPESEYYKCASILEKFFFSKIKEAGLIDK TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001190846 |
| ORF Size | 2205 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001190846.1, NP_001177775.1 |
| RefSeq Size | 4100 bp |
| RefSeq ORF | 2208 bp |
| Locus ID | 18519 |
| Gene Summary | Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Also acetylates non-histone proteins, such as ACLY, PLK4 and TBX5. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Involved in heart and limb development by mediating acetylation of TBX5, acetylation regulating nucleocytoplasmic shuttling of TBX5. Acts as a negative regulator of centrosome amplification by mediating acetylation of PLK4. Also acetylates spermidine (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MR225908 | Kat2b (Myc-DDK-tagged) - Mouse K(lysine) acetyltransferase 2B (Kat2b), transcript variant 2 |
CNY 5,384.00 |
|
| MR225908L3 | Lenti ORF clone of Kat2b (Myc-DDK-tagged) - Mouse K(lysine) acetyltransferase 2B (Kat2b), transcript variant 2 |
CNY 7,700.00 |
|
| MR225908L4 | Lenti ORF clone of Kat2b (mGFP-tagged) - Mouse K(lysine) acetyltransferase 2B (Kat2b), transcript variant 2 |
CNY 7,700.00 |
