Faim2 (NM_028224) Mouse Tagged ORF Clone
CAT#: MR204553
- TrueORF®
Faim2 (Myc-DDK-tagged) - Mouse Fas apoptotic inhibitory molecule 2 (Faim2), transcript variant 1
"NM_028224" in other vectors (3)
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CNY 2,400.00
Cited in 1 publication. |
CNY 300.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | 2900002L20Rik; Lfg; Lfg2; NMP25; Nmp35; Tmbim2 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MR204553 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACCCAGGGAAAGCTCTCTGTGGCTAACAAGGCCCCCGGGACTGAGGGGCAGCAGCACCAGGCAAATG GAGAGAAGAAGGATGCTCCGGCAGTGCCCTCGGCGCCACCCTCCTATGAGGAGGCCACCTCTGGAGAGGG GCTGAAGGCAGGGACCTTCCCCCAGGGCCCAACAGCTGTGCCACTCCATCCAAGCTGGGCCTACGTGGAC CCCAGCGGCAGCTCCGGCTATGAAGGTGGTTTCCCCGCAGGACATCACGAGCATTTCACCACCTTCAGCT GGGATGACCAGAAAGTTCGTCGGCTCTTCATCAGAAAGGTCTATACCATCCTATTGGTCCAGCTGCTGGT GACCTTGGCTGTGGTGGCTCTCTTTACCTTCTGTGATGTCGTTAAGGACTATGTCCAGGCTAACCCCGGC TGGTACTGGGCGTCCTATGCCGTGTTCTTTGCAACTTACCTGACTCTGGCTTGCTGTTCTGGACCCAGGA GACATTTCCCTTGGAACCTGATTCTGCTGACCATCTTTACCCTGTCCATGGCCTACCTCACTGGGATGCT GTCCAGTTACTACAACACCACATCTGTGCTGCTGTGCCTGGTCATCACGGCTCTCGTCTGCCTCTCGGTC ACCATCTTCAGTTTCCAGACCAAGTTTGACTTCACCTCCTGTCAGGGTGTGCTGTTTGTGCTGCTCATGA CCCTCTTCTTCAGTGGACTCCTCCTCGCTGTCCTCCTGCCCTTCCAATACGTCCCCTGGCTCCACGCGGT CTATGCTGTACTGGGAGCGGGTGTGTTCACGTTGTTCCTGGCCTTTGATACCCAGTTGCTGATGGGTAAC CGTCGACACTCGCTGAGCCCCGAGGAGTATATTTTTGGAGCCCTCAACATCTACTTAGACATTATCTATA TCTTCACCTTCTTCCTGCAGCTTTTTGGCACCAACCGGGAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR204553 protein sequence
Red=Cloning site Green=Tags(s) MTQGKLSVANKAPGTEGQQHQANGEKKDAPAVPSAPPSYEEATSGEGLKAGTFPQGPTAVPLHPSWAYVD PSGSSGYEGGFPAGHHEHFTTFSWDDQKVRRLFIRKVYTILLVQLLVTLAVVALFTFCDVVKDYVQANPG WYWASYAVFFATYLTLACCSGPRRHFPWNLILLTIFTLSMAYLTGMLSSYYNTTSVLLCLVITALVCLSV TIFSFQTKFDFTSCQGVLFVLLMTLFFSGLLLAVLLPFQYVPWLHAVYAVLGAGVFTLFLAFDTQLLMGN RRHSLSPEEYIFGALNIYLDIIYIFTFFLQLFGTNRE TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_028224 |
ORF Size | 954 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_028224.4, NP_082500.2 |
RefSeq Size | 4668 bp |
RefSeq ORF | 954 bp |
Locus ID | 72393 |
UniProt ID | Q8K097 |
MW | 35.3 kDa |
Gene Summary | Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. Plays a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development.[UniProtKB/Swiss-Prot Function] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
---|
EPO regulates neuroprotective Transmembrane BAX Inhibitor-1 Motif-containing (TMBIM) family members GRINA and FAIM2 after cerebral ischemia-reperfusion injury
,Habib, P;Stamm, AS;Zeyen, T;Noristani, R;Slowik, A;Beyer, C;Wilhelm, T;Huber, M;Komnig, D;Schulz, JB;Reich, A;,
Exp. Neurol.
,PubMed ID 31211943
[FAIM2]
|
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC207722 | Faim2 (untagged) - Mouse Fas apoptotic inhibitory molecule 2 (Faim2), transcript variant 1, (10ug) |
CNY 3,990.00 |
|
MR204553L3 | Lenti ORF clone of Faim2 (Myc-DDK-tagged) - Mouse Fas apoptotic inhibitory molecule 2 (Faim2), transcript variant 1 |
CNY 4,750.00 |
|
MR204553L4 | Lenti ORF clone of Faim2 (mGFP-tagged) - Mouse Fas apoptotic inhibitory molecule 2 (Faim2), transcript variant 1 |
CNY 4,750.00 |