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Cops2 (BC023096) Mouse Tagged ORF Clone
CAT＃: MR207016
- TrueORF®
Cops2 (Myc-DDK-tagged) - Mouse COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana) (cDNA clone MGC:18349
ORF Plasmid: tGFP
"BC023096" in other vectors (4)
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CNY 3,656.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | Sgn2, Trip15, alien-like, Csn2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR207016 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGGATGATTTCATGTGCGATGATGAGGAGGACTACGACCTGGAGTACTCTGAAGACAGTAACTCTG AGCCCAATGTGGATTTGGAAAATCAGTACTATAATTCCAAAGCACTGAAAGAAGATGACCCAAAAGCAGC ATTAAGCAGCTTCCAAAAGGTTTTGGAGCTTGAAGGTGAGAAGGGAGAATGGGGATTCAAAGCGCTAAAA CAGATGATCAAGATTAACTTCAAGTTGACAAACTTTCCAGAAATGATGAACAGATATAAGCAACTATTGA CCTATATTCGGAGTGCAGTCACCAGGAACTATTCTGAAAAGTCCATTAATTCTATCCTTGATTATATCTC CACTTCTAAACAGATGGATTTACTGCAGGAATTTTATGAAACAACACTGGAAGCTTTGAAAGATGCTAAG AATGATAGACTGTGGTTTAAGACAAACACAAAGCTTGGAAAATTATATTTAGAACGAGAAGAATATGGAA AGCTTCAAAAAATTTTACGACAGTTACATCAGTCTTGTCAGACTGATGATGGAGAAGATGACCTGAAAAA AGGTACCCAGTTATTAGAAATCTATGCTTTGGAAATTCAAATGTACACTGCACAGAAGAACAACAAAAAG CTTAAAGCACTCTATGAGCAATCACTTCACATCAAGTCTGCCATCCCTCACCCACTAATCATGGGTGTCA TCAGAGAATGCGGTGGTAAAATGCACTTGAGAGAAGGTGAATTTGAAAAGGCACACACTGATTTTTTTGA AGCCTTCAAGAATTATGATGAATCAGGAAGCCCAAGACGAACCACTTGTTTAAAATATTTGGTTTTAGCA AATATGCTAATGAAATCAGGAATAAATCCGTTTGACTCACAAGAGGCCAAGCCGTATAAAAATGATCCAG AAATTCTAGCAATGACAAATTTAGTAAGTGCCTATCAGAATAATGACATCACTGAATTTGAAAAGATTCT GAAAACAAATCACAGCAACATCATGGATGATCCTTTCATAAAAGAGCACATTGAAGAGCTTTTACGAAAC ATCAGAACACAAGTCCTCATAAAGTTAATTAAGCCTTACACAAGAATACATATTCCTTTTATTTCTAAGG AGCTAAACATAGACGTAGCTGATGTGGAGAGCTTGCTGGTGCAGTGCATACTGGATAACACTATTCATGG CCGAATTGATCAAGTCAACCAGCTCCTTGAACTGGATCATCAGAAGAGGGGTGGTGCCCGATACACTGCG CTAGATAAATGGACCAACCAACTAAATTCTCTGAACCAGGCTGTGGTCAGTAAACTGGCT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR207016 protein sequence
Red=Cloning site Green=Tags(s) MEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKALK QMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALKDAK NDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKK LKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLA NMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIKEHIEELLRN IRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTA LDKWTNQLNSLNQAVVSKLA TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | BC023096 |
| ORF Size | 1320 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC023096, AAH23096 |
| RefSeq Size | 1951 bp |
| RefSeq ORF | 1322 bp |
| Locus ID | 12848 |
| MW | 51.2 kDa |
| Gene Summary | Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC218154 | Cops2 (untagged) - Mouse COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana) (cDNA clone MGC:18349, (10ug) |
CNY 6,940.00 |
|
| MG207016 | Cops2 (tGFP-tagged) - Mouse COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana) (cDNA clone MGC:18349 |
CNY 2,760.00 |
|
| MR207016L3 | Lenti ORF clone of Cops2 (Myc-DDK-tagged) - Mouse COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana) (cDNA clone MGC:18349 |
CNY 4,370.00 |
|
| MR207016L4 | Lenti ORF clone of Cops2 (mGFP-tagged) - Mouse COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana) (cDNA clone MGC:18349 |
CNY 4,370.00 |
