Amotl2 (NM_019764) Mouse Tagged ORF Clone
CAT#: MR207385
- TrueORF®
Amotl2 (Myc-DDK-tagged) - Mouse angiomotin-like 2 (Amotl2)
ORF Plasmid: tGFP
"NM_019764" in other vectors (4)
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CNY 5,664.00
CNY 5,800.00
CNY 300.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | AW549739; C79691; Lccp; MASCOT; mKIAA0989 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MR207385 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAGGACACTGGAAGACTCCTCAGGGACAGTCCTGCACCGTCTCATCCAAGAGCAGCTGCGCTACGGCA ACCTGACAGAGACTCGCACTCTGCTGGCTATCCAGCAGCAGGCCCTGCGGGGTGGGGCTGGAGCTGGGGG CACGGGGAGCCCCCAGGCTTCCTTGGAGATCGGAGCACCCGAGGACAGTCAGGTGCTGCAGCAAGCCACC AGGCAGGAGCCCCAGGGCCAGGAGCATCAGGGTGGAGAGACCCACCTGGCAGAGAACAGGCTGTACCGGC TGTGCCCACAGCCCAGCAAAGGAGAAGAGTTGCCCACCTATGAGGAGGCCAAAGCCCATTCGCAGTACTA CGCAGCGCAGCAGGCAGGGTCCCGGCCGCATGTTGGGGACCGGGATCCTAGAGGAGGGGTGTCCGGAGGC GGCCGGCGACAGGATGAAGCTCTTCGAGAGCTGAGGCATGGCCATGTGCGCTCCTTGAGTGAACGGCTTC TGCAACTGTCCCTGGAAAGAAACGGTGCTCGGGTCCCCAGCCACATGAGCTCTTCCCACAGCTTCCCTCA GCTGGCCCGCAGCCAGCAGGGCCCCCAACCCCGAGGGCCCCCAGCTGAGGGCCCAGAGCCCCGCGGGCCA CCACCTCAGTACCCACACGCTGTAATGGCTCAGGAGACTGCGGCTGTCACTGACCCAAGATACCGACCCC GAAGCAGCCCACACTTCCAGCATGCCGAAGTCAGGATCCTGCAGGCCCAGGTACCACCGGTGTTCCTCCA GCAGCAGCAGTACCAGTACCTGCCGCAGCCCCAGGAGCACTCTCCACCCCTCCACCCGGCAGCTCTGGGC CATGGACCCCCAAGCTCCTTTGGTCCACCTGCAGTGGAGGGACCACCCAGTGCCCAGGCCACCTTGGGCA GTGCCCACCTGGCCCAGATGGAGACTGTACTGAGGGAGAATGCCAGGCTGCAGAGGGACAATGAGCGATT GCAGAGAGAGCTGGAGAGCACTTCAGAGAAGGCTGGCCGCATAGAAAAGCTGGAAAATGAAATCCAGCGG CTCTCTGAGGCCCACGAGAGCCTGATGAGGACCTCTTCCAAGCGTGAGGCCCTGGAGAAGACCATGAGGA ACAAGATGGACGGTGAGATGAGACGGTTGCAGGACTTCAACCGAGACCTTAGAGAGAGATTGGAATCGGC AAACCGCCACCTGGCAAGCAAGACCCAGGAAGCCCAGGCGGGCAGTCAGGACATGGTGGCGAAACTGCTT GCCCAGAGCTATGAGCAGCAACAGGAACAGGAGAAGCTGGAGCGGGAGATGGCACTGCTGCGTGGTGCCA TCGAGGACCAGCGGCGACATGCTGAACTGCTGGAGCAGGCTCTGGGCAATGCACAAAGCCGTGCCGCCCG GGCTGAAGAGGAGCTACGCAAAAAGCAGGCCTATGTGGAGAAGGTGGAGCGGCTGCAGCAGGCACTGGGG CAGTTGCAGGCTGCCTGTGAAAAGCGAGAGCAGTTGGAGCTGCGTCTGCGCACGCGCCTGGAGCAGGAAC TCAAAGCCTTGCGTGCACAGCAGAGGCAGACAGGCACCCTCGCAGGTGGTGGCGGCAGCCATGGTGGGTC CGCCGAGCTCAGTGCCCTGCGGCTGTCTGAACAGCTGCGGGAGAAGGAGGAACAGATCCTGGCTCTAGAG GCGGACATGACCAAGTGGGAACAGAAGTATTTGGAAGAACGGGCTATGAGGCAGTTCGCCATGGACGCGG CTGCCACTGCGGCTGCCCAGCGCGATACCACTCTCATCCGGCACTCCCCCCAGCCCTCGCCCAGCAGCAG TTTCAACGAGGGCCTGCTGCCAGGCAACCACAGGCACCAGGAGATGGAGAGCAGATTGAAGGTGCTCCAT GCTCAGATCCTAGAGAAGGATGCGGTGATCAAGGTCCTTCAGCAGCGCTCCAGGAAAGACCCTGGCAAGG CCACCCAGGGCACCCTACGGCCTGCCAAGTCGGTGCCGTCCATCTTCGCGGCTGCAGTGGGAACTCAGGG CTGGCAAGGGCTCGTATCCAGTGAGCGGCAAACTGATGCACGGCCAGCGGGAGACCGGGTCCCAGCAGAG GAGCCTCCGGCCACAGCTCCTCTCCCTGCCCACACCAAACATGGCAGCAGAGACGGGAGCACCCAGACGG ATGGCCCTGCAGACAACACCTCTGCCTGCTTGGCCTCAGAACCCGATGGCCTCCTGGGGTGCAACAGTAG CCAGAGGACACCCTCTCTGGACTCTATAGCTGCAACCAGAGTCCAGGATCTGTCAGACATGGTAGAAATA CTGATC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR207385 protein sequence
Red=Cloning site Green=Tags(s) MRTLEDSSGTVLHRLIQEQLRYGNLTETRTLLAIQQQALRGGAGAGGTGSPQASLEIGAPEDSQVLQQAT RQEPQGQEHQGGETHLAENRLYRLCPQPSKGEELPTYEEAKAHSQYYAAQQAGSRPHVGDRDPRGGVSGG GRRQDEALRELRHGHVRSLSERLLQLSLERNGARVPSHMSSSHSFPQLARSQQGPQPRGPPAEGPEPRGP PPQYPHAVMAQETAAVTDPRYRPRSSPHFQHAEVRILQAQVPPVFLQQQQYQYLPQPQEHSPPLHPAALG HGPPSSFGPPAVEGPPSAQATLGSAHLAQMETVLRENARLQRDNERLQRELESTSEKAGRIEKLENEIQR LSEAHESLMRTSSKREALEKTMRNKMDGEMRRLQDFNRDLRERLESANRHLASKTQEAQAGSQDMVAKLL AQSYEQQQEQEKLEREMALLRGAIEDQRRHAELLEQALGNAQSRAARAEEELRKKQAYVEKVERLQQALG QLQAACEKREQLELRLRTRLEQELKALRAQQRQTGTLAGGGGSHGGSAELSALRLSEQLREKEEQILALE ADMTKWEQKYLEERAMRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLPGNHRHQEMESRLKVLH AQILEKDAVIKVLQQRSRKDPGKATQGTLRPAKSVPSIFAAAVGTQGWQGLVSSERQTDARPAGDRVPAE EPPATAPLPAHTKHGSRDGSTQTDGPADNTSACLASEPDGLLGCNSSQRTPSLDSIAATRVQDLSDMVEI LI TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_019764 |
ORF Size | 2319 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_019764.2, NP_062738.2 |
RefSeq Size | 4191 bp |
RefSeq ORF | 2319 bp |
Locus ID | 56332 |
UniProt ID | Q8K371 |
MW | 85.3 kDa |
Gene Summary | Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC201937 | Amotl2 (untagged) - Mouse angiomotin-like 2 (Amotl2), (10ug) |
CNY 5,664.00 |
|
MG207385 | Amotl2 (tGFP-tagged) - Mouse angiomotin like 2 (Amotl2) |
CNY 6,370.00 |
|
MR207385L3 | Lenti ORF clone of Amotl2 (Myc-DDK-tagged) - Mouse angiomotin-like 2 (Amotl2) |
CNY 7,700.00 |
|
MR207385L4 | Lenti ORF clone of Amotl2 (mGFP-tagged) - Mouse angiomotin-like 2 (Amotl2) |
CNY 7,700.00 |