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Hdac10 (NM_199198) Mouse Tagged ORF Clone
CAT＃: MR209891
- TrueORF®
Hdac10 (Myc-DDK-tagged) - Mouse histone deacetylase 10 (Hdac10), transcript variant 1
ORF Plasmid: tGFP
"NM_199198" in other vectors (4)
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CNY 4,888.00
CNY 5,800.00
| Cited in 1 publication. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | AW548891; Hd10 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR209891 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGCACAGCACTTGTGTACCACGAGGACATGACAGCCACTCGACTGCTCTGGGATGACCCCGAGTGCG AAATTGAGTGCCCAGAGCGCCTGACAGCTGCCCTGGATGGCCTGCGGCAGCGTGGCCTGGAAGAAAGGTG CCTGTGTTTGTCAGCTTGTGAGGCATCAGAGGAAGAGTTGGGCTTGGTGCACAGCCCGGAATATATAGCC CTGGTGCAGAAGACCCAGACCCTGGATAAAGAGGAGCTCCACGCACTGTCTAAGCAGTACGATGCTGTCT ACTTTCACCCGGACACCTTTCACTGTGCCCGGCTGGCAGCGGGGGCTGCACTGCAGCTGGTCGATGCTGT GCTAACAGGAGCTGTGCACAATGGGCTTGCCCTGGTGAGGCCTCCAGGGCACCACAGTCAGAGGGCAGCT GCCAATGGATTCTGTGTGTTCAACAATGTGGCTCTAGCAGCCAAACATGCCAAGCAGAAATATGGGCTGC AGAGGATTCTCATTGTCGACTGGGATGTCCACCATGGCCAGGGCATCCAGTATATCTTCAACGATGACCC CAGTGTCCTTTATTTCTCTTGGCACCGCTATGAGCATGGAAGCTTCTGGCCGTTTCTCCCAGAGTCTGAT GCAGATGCAGTTGGCCAAGGGCAGGGCCAAGGTTTCACTGTCAATTTGCCCTGGAACCAGGTTGGGATGG GAAATGCCGACTATTTGGCTGCCTTTCTGCATGTGCTGCTCCCACTGGCCTTCGAGTTTGATCCTGAGTT GGTGCTGGTGTCGGCTGGATTTGACTCTGCTATCGGGGACCCTGAGGGGCAGATGCAGGCCACCCCTGAG TGCTTTGCCCATCTCACACAGCTGCTGCAGGTGCTGGCTGGTGGCCGGATTTGTGCTGTGTTGGAGGGTG GCTACCACTTGGAGTCCCTAGCACAGTCAGTGTGCATGATGGTGCAGACACTGCTTGGTGACCCCACACC TCCCCTTCTTGGGCTCATGGTGCCATGTCAGAGTGCCCTGGAGTCCATCCAGAGTGTCCAGACAGCCCAG ACCCCTTACTGGACAAGCCTCCAGCAAAATGTGGCCCCAGTTCTGAGTTCCAGCACCCACTCTCCTGAAG AGAGATCTCTGCGTCTGCTTGGTGAGAGCCCCACATGCGCAGTAGCAGAAGATTCACTGAGCCCCCTCCT GGACCAACTGTGCCTCCGCCCTGCACCTCCAATCTGCACAGCGGTGGCCTCGACTGTACCAGGTGCTGCT CTGTGCTTACCTCCTGGAGTGCTCCATCAAGAAGGGTCAGTCTTGAGGGAGGAGACCGAAGCCTGGGCCA GGCTTCACAAATCCCGGTTCCAGGATGAGGATCTTGCCACACTGGGGAAGATTCTGTGTCTCTTAGATGG AATCATGGATGGGCAGATAAGAAATGCCATAGCAACCACAACTGCCCTCGCCACAGCAGCAACATTGGAT GTACTCATTCAGCGATGCCTAGCTCGCAGAGCTCAGAGGGTGCTCTGTGTGGCCCTGGGACAACTGGATC GACCCCTGGACCTTGCAGATGATGGGAGAATTCTGTGGCTCAACATCCGGGGCAAGGATGCAGCCATCCA GTCCATGTTCCACTTCTCCACTCCACTGCCACAGACAACTGGAGGGTTTCTGAGCCTCATTCTGGGTCTG GTACTGCCCTTGGCCTATGGTTTCCAGCCTGATATGGTGTTGATGGCACTGGGGCCTGCCCATGGCCTGC AGAACGCTCAAGCTGCTCTCTTGGCTGCAATGCTTCGGAGCCCAGTAGGGGGCCGAATTCTAGCTGTAGT GGAAGAGGAATCCATACGCCTGCTTGCAAGGAGCCTGGCGCAGGCATTGCATGGAGAAACACCTCCCAGT CTGGGTCCTTTCTCGAAGGCCACTCCAGAGGAGATCCAGGCTCTGATGTTTCTAAAAGCTCGGCTGGAGG CTCGCTGGAAATTGCTGCAGGTGGCTGCTCCTCCACCA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR209891 protein sequence
Red=Cloning site Green=Tags(s) MGTALVYHEDMTATRLLWDDPECEIECPERLTAALDGLRQRGLEERCLCLSACEASEEELGLVHSPEYIA LVQKTQTLDKEELHALSKQYDAVYFHPDTFHCARLAAGAALQLVDAVLTGAVHNGLALVRPPGHHSQRAA ANGFCVFNNVALAAKHAKQKYGLQRILIVDWDVHHGQGIQYIFNDDPSVLYFSWHRYEHGSFWPFLPESD ADAVGQGQGQGFTVNLPWNQVGMGNADYLAAFLHVLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPE CFAHLTQLLQVLAGGRICAVLEGGYHLESLAQSVCMMVQTLLGDPTPPLLGLMVPCQSALESIQSVQTAQ TPYWTSLQQNVAPVLSSSTHSPEERSLRLLGESPTCAVAEDSLSPLLDQLCLRPAPPICTAVASTVPGAA LCLPPGVLHQEGSVLREETEAWARLHKSRFQDEDLATLGKILCLLDGIMDGQIRNAIATTTALATAATLD VLIQRCLARRAQRVLCVALGQLDRPLDLADDGRILWLNIRGKDAAIQSMFHFSTPLPQTTGGFLSLILGL VLPLAYGFQPDMVLMALGPAHGLQNAQAALLAAMLRSPVGGRILAVVEEESIRLLARSLAQALHGETPPS LGPFSKATPEEIQALMFLKARLEARWKLLQVAAPPP TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_199198 |
| ORF Size | 2001 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_199198.1, NP_954668.1 |
| RefSeq Size | 2424 bp |
| RefSeq ORF | 2001 bp |
| Locus ID | 170787 |
| UniProt ID | Q6P3E7 |
| MW | 72.1 kDa |
| Gene Summary | Polyamine deacetylase (PDAC), which acts preferentially on N(8)-acetylspermidine, and also on acetylcadaverine and acetylputrescine. Exhibits attenuated catalytic activity toward N(1),N(8)-diacetylspermidine and very low activity, if any, toward N(1)-acetylspermidine. Histone deacetylase activity has been observed in vitro. Has also been shown to be involved in MSH2 deacetylation. The physiological relevance of protein/histone deacetylase activity is unclear and could be very weak. May play a role in the promotion of late stages of autophagy, possibly autophagosome-lysosome fusion and/or lysosomal exocytosis in neuroblastoma cells. May play a role in homologous recombination. May promote DNA mismatch repair.[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
HDAC10 deletion promotes Foxp3+ T-regulatory cell function
,Dahiya, S;Beier, UH;Wang, L;Han, R;Jiao, J;Akimova, T;Angelin, A;Wallace, DC;Hancock, WW;,
Sci Rep
,PubMed ID 31949209
[HDAC10]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC204849 | Hdac10 (untagged) - Mouse histone deacetylase 10 (Hdac10), transcript variant 1, (10ug) |
CNY 4,888.00 |
|
| MG209891 | Hdac10 (tGFP-tagged) - Mouse histone deacetylase 10 (Hdac10) |
CNY 6,488.00 |
|
| MR209891L3 | Lenti ORF clone of Hdac10 (Myc-DDK-tagged) - Mouse histone deacetylase 10 (Hdac10), transcript variant 1 |
CNY 7,700.00 |
|
| MR209891L4 | Lenti ORF clone of Hdac10 (mGFP-tagged) - Mouse histone deacetylase 10 (Hdac10), transcript variant 1 |
CNY 7,700.00 |
