Setx (NM_198033) Mouse Tagged ORF Clone

Specifications

Product Data
Type	Mouse Tagged ORF Clone
Tag	Myc-DDK
Synonyms	A130090N03; A930037J23Rik; Als4; AOA2; AW060766; mKIAA0625; SCAR1; Sen1
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	ORF Nucleotide Sequence (showhide) >MR217962 representing NM_198033 Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAGCACATGCTGTTGGTGTACTCCAGGTGGGTCTTCCACCATTGATGTCCTAAAGCGCTATGCATCTA GCACTGGGTCAAGTGAATTTCAGACAGCTGATGAAGACCTCTGCTACTGCTTAGAGTGTGTGGCTGAGTA CCACCGAGCCAGAGATGAGGTGCCGTTCTTGCACGAGGTTTTATGGGAGCTAGAAACCTTACGCCTCGTA AGTCACTTTGAGAAGTCCATGAAGGCAGAAGCTGAAGATGACGATGATTTATATATAGTAGACAACAATG GAGAGGAACAGCTGTTTGACTGTAGTGGCCAAGATTTTGAAAATAAGCTTCGAGTTCCTCTTTTTGAAAT ACTGAAGTACCCTTACTTGCTTCTGCATGAGCGTGTTAATGAACTGTGTGTGGAAGCGCTTTGCCGAATG GAACAAAACAATTGCTCCTTTCAGGTTTTTGACAAATATCCAGGCATCTATTTGTTTTTGGTTCATCCCA ATGAAATGGTTCGGCGATGGGCTATTCTGACTGCAAGAAACCTGGGGAAGGTGGACAGAGATGACTATTA TGACTTACAGGAAGTTTTAACTTGCCTTTTTAAAGTCATTGAGCTGGGGCTTTTGGAAAGTCCAGACATT TACACATCTTCTGTGCTTGAAAAAGGCAAACTGATCCTTTTGCCTGCACACATGTATGATACTACCAACT ACAAAAACTATTGGCTAGGTATTTGCATGTTGTTGACTATTCTTGAGGAGCAAGCCATGGATTCACTGTT GCTGGGCTCAGACAAGCAAAATGATTTTATGCAATCAATTCTTCACACCATGGAGAAGCAATCGGATGAT GATAGCATGGATCCTTTTTGGCCAGCATTACACTGTTTCATGGTGATTCTTGATCGCCTTGGATCTAAGG TATGGGGTCAACTTATTGACCCTATTGAAGCATTTCAAACCATCATTAACAACGAGAGCTACAACAGAGA GATCCAGAATATACGGAACAGCTCCATAAGGACCAAGTTAGAACCGGAGCCACATTTTGATGATATGGTG ACGTGCAGCCAGATTGTTTATAACTTTAATCCTGAAAAGACCAAAAAGGATTCTGGGTGGAGATCAGCCA TTTGTCCAGATTATTGTCCAAACATGTATGAAGAAATGGAAACATTAGCCAATGTACTTCAGTCAGATAT TGGTCAAGATATGCGTGTTCATAACAGCACCTTTCTGTGGTTCATACCTTTTGTTCAGTCACTCATGGAT CTTAAGGATTTGGGTGTGGCTTACATAGTAGAAGTTATTCATCATCTATACTCAGAAGTCAAAGATGTCC TCAACCAGACAGATGCTGTGTGTGACAAAGTCACTGAATTTTTTATTCTGATTTTAATATCAGTGATTGA GCTGCATAGAAATAAAAAATGCTTGCATCTGCTGTGGGTGAGTTCTCAGCAGTGGGTAGAAGCTGTTGTG AAGTGTGCCAAGCTTCCTACTACCGCATTTGTCCGGAGTTGTGAGAAGTCACCTGGAAGTACCTCCAGAG GAGCAGCAATAATGTCGTCCTTGGCGTTGCATTCGGTGCAGTCTAACTCTGTCCAGCTTGCTTGTGTACA GTTGATTAGAGGTCTCCTCAAAGAAGGTTATCAGCTTGGTCAGCAAACACTTTGTAAGCGGTTCTGGGAT AAGCTTAACTTATTCCTTCGAGGAAATTTGTCTCTGGGTTGGCAATTGACTGGTCAAGAAACCCATGAGT TACAAATGTGTTTGAAACAAATAATTAGAAACATAAAATTCAAAATGCCCCAATATAGCACTTTTGGGGA TTCAACTTCTACATTTAAAACCCCTCCATCTTTTAAAGAAGAAAGTGATAAAATAGACAGGAAGCATAAA AAAAACATTTATTGTTTGGAAAATTGCAGTCCAGTGTCTTCTAAAGAGCCAATGAAAGCTGACACCCATC GAGTATTGATGAAAGTAAATACTACAGAAGAGGAGAACTTCAAGCAGCATTACATTGATTTGAATGAAGA AGAGCAAGAGCCTCTTCCAGCTGAGTTGTGCTTGAAGCAGAAAAGTGAGGCCCTTTTTTCTGAAAGTGCT CAAGAGCAAGTTAAAATTAGCGCAGAGAAGTCTGGGAAAGAAAGCTCTTCATATGCACCATCAAATAGTA CTTCAAGAAATGGTCCAGAATGGGGATGTGACAGAGGAGTGATAATGTCAGCACATTCATTGACTGATTC TAGCAGTGATTTTATGGAACAGGTATCTACATCAAATGAAGATGTCTCATTAAAGGATGGCTCTGTTGGT AAAACTTCAAAACCAAGTTTCAAATTACAGAAAGATGAAATTTGTGCAAAGTTATCACATGTCATAAAGA AGCAAATCAGGAAAAGTACTTTGGTAGATAATATTATCGATCTAGAGGAAAATACAGCTATATCTGACCT TGAGAACTGTTCAGGAACAGATGGAGGAGCTCTAAAGGAAGATAGTATTGGACACAATGTCCCTTCAGAC CCTGTTCTGGATGACAAGCATGAAGAGCAAAAATCTCAAAACAGTTCATTATTCAAGAAAGAGATAAAGA GTGAGGAGTTGGATAATAGTAGTTCTGATGATGAAGACAAGCTTCAAATCCAGGAAGGCCGTGCTGACGA TGATTTGGTATCATTTACAGAAGTTACTGATACACTGGTGAAAGCTCCATGTGAGGGTCATGTAAAGATG GTAGTTGAATCAAGAGATAAGGAAATGAGAGAGAGTACAGCGTTGACTTCTAACTTGGTAGAAGGACAGG TGCCTCATGACAGTAGCAAGCCTTTGGTTGCAGGTCGTCAAATAGACCTCTGTAACATAACTTTAATATC TCAAACCACTGTTATTCAATTTCCATCAGGTTTAAGTAAACAGAATTCATTTCAGCTACAAAAAGGTGAT AAAAGATGTTTGACAGCTAACCAAAACAGTGCTGCCACCTGCCGTGGACAAGTTATTGTGATTTCAGATT CTGACGAAGAAGAGGATGAGGATGAAGATGAAAGAAGTAGTAGTGAGGAAAACATCAAACAGAGTAAAGC ATGCATAGGGAAAGACTGCTCAGAGCATCGTAGCTTGGCAGTTAATGCCAGTGTGGAGAAGCAGCTTGTA AAAGAGGAAGAAAGGTACCCTGTAGAATTTGAAGACTCTGAATCTCAGGTTTTTGAGTTTGAAAGCTCAT CTGAAGTCTTTTCAGTTTGGCAAGATCATAAAATAGACAGCAAAAACTCCCTTCAAGGGGAACAGAAGAG CTATGTAACTCATGTAGCTGATAGTACAAACAATAACTTGGGTTGTGGTGACTCTGTGTCTGAAGAGGTT GTTAGAAACAAAGCAGAGGGAGTTAAAGAGCATGCAGGACCACATAGTAGTGTTTCTGCTGAGGAATTTT GTAAAACTGGAGTAAAAAAACCTAAGAGGAAACGCTATGACAAAGTTACAGCTGAAGATCCTCAGAGGCC TTCCTCTTCTGTTGGAACTGATCAATTGCCTGATCGCAGAGATCTTACTGAAAGTGATTTAAAGAGTGCA GACATGGGGATGGCAACTCCCAGTTCAAGTGTTGAGAGAGATTCTACAATTTTACAGAAGTCTACAAAAT CTCGAACTCACTCAAAACCTGTTAGGAAAGTTCCAGCCTCTAAGGCAACTAAGAAAACACATTCAGACAC CAGAAGAGGACAGTCTAAGAGTTCATGTTACATAAGTTGTAGAACTTCTCCTGCTATTGTGCCACCAAAG AAGCTTCGTCAGTGTCCAGAGCCAACTTCAACAGTTGAAAAACTTGGTCTGAAAAAAGCCCCTAGGAAGG CATTTGAGTTGTCCCAGAGGTCTCTGGAGTGTATAGTCCAATTACGTGACCACGGGAAGACTGTTGGAGT AGTTGACGCCCCCAAGAAAGCTAAATTAATTTCTCCTCAGACTCTTTCTATCAAAAATAATAAGAAGCTT CTGACAAGCCAGGATCTTCAATTTCAAAGGCTTATGAGATCCAGATCACATAAAAAACGAGACTTTGATT ACAAAAATACTGATACTGTAAGAGTGTCACGCATAGTACAGGGATCAGATGTACTTGAAGCAGACTCTGA TGAGCCAGATGATCATAGAGTAAGTGAGCCACTTGCCATCAGTAATGAAAAACAGTTAGCAAAATGCATG CTTTCCAAAACAGAAGTGGCAGAAGCCTCTTCTGATCCTTGGGTGACAGGTATAACTTGTCTTGTGAACC AGTGTGAATCTAGAGTGTTAAGTGGAGGAGTGCCAACAGATGTGGTGATGGTCTCTGCTTCAGAGGACCC TGTGGATGGAGGTGCTGTCACAGTTCAAGTTGGGGAGGTGGCATCTGTGAAAGCTGCAGAGCCAGCGTCT AGTAGTGATACAGATGATGATGACAACTTATTCCTAACACAACATGATCCTCAAGATATGGATCTGTGCT CACAGTTGGAAAATAAAACCATTATCGTGGCTCATAAAAAAGATACAGTTCAGAGAGAAGATTCTTTAAG TCGGCCTCAGTTGGAGTCTTTGAGTATCACAAAGTGTAAATACAAAGACTGTGTCGAAACTACAAAAAAC CAGGGTGAATACTGCCCAAGACACTCTGAAGCTAAAGCAGCAGATGACGGCCTGTTCCGTAAACCTGGCT TGCCTCTTTCTGTAGCCAGGCCCTTGAGACCTACTACTACCAAGATATTTAGCTCAAGCAGCGCTTCACG AACTGCCAATCTTTCCAAGTCTTTGGAAAGTACTACACTTCAGCAGTCAGCACTAAAAAATAAGTCAAGT GGAGCGCAGCCTAATTTGAAGGTGACACCACCCTCTTCCATGGGTTCTCAGAAGCCAGTGGCTGAGGTGA AAAGTCTATGCAATATTTTTCATTTTCAGACTCCAAGCAGTTCCAGCAAACAGAGTTGCAAGCTTACATT TAGTGAGAACAGGCCTACATCAGCTGCTTCTCCAGTGAATATTCTCTTGCCATCGCAGTCTATCTTTGAC ACCTTCATTAAAGAGGTCTTAAAATGGAAATACCAAATGTTTTTGAACTTTGATAAGTGTGGTGCTCCAA CAAGTCTCTGTCAGTCTATCTCAAGACCTGTGCCTGTCCGATTTCAAGATTGTGCAGAATATTTTAATGT TTTTCTACCTTTGATTATATTGAATGCTTTTGAAACAGTGGCACAGGAATGGCTGAGCTCTCCAAATAAA GAGAATTTCTATCAGTTGCAATTACGAAAATTTCCAGCTGACTATAAAAAATACTGGGAGTTTCTGATTT ACTTGAACGAATCTGAACTTGCTAAACAGCTTCACCCAAAGGAAAATGATCTGGTGTTTCTGGCTCCTGA GAAGAGTTATATGGACAGGCATGGCATGCAAGATTGCAGTCACTATTACTGTGGCTATGTTCATAAGTTT CGTCGCACTTCAGTTATGCGCAGTGGGAAAGCTGAGTGTTCATTATGCATACAGACACAAGATACCTTGC CAGCCAGTGTAAAAAATCTTACAAGATGCATTGTGATCAGTTCTCTGGTAACTACACAGAGGAAATTGAA AGCCATGTCTCTGTTGAGTAGTCGGAACCAGTTGGCCAGAGCTGTTCTAAATCCAAACCCCATGGACTTC TGTACCAAAGATCTACTAACTACAACTTCTGAAAGAATTGTTGCCTACTTAAAAGACTTTAATGAAGACC AAAAGAAAGCCATAGAAACTGCATATGCCATGGTGAAACACTCACCATCCGTTGCCAAAATCTGTCTGAT TCATGGACCACCTGGAACAGGAAAATCCAAAACTATTGTTGGTCTCTTGTACCGCTTACTGACAGAGAAC CAGAGGAAGGGCCATTCAGATGAAAATTTCAATGCCAAAATCAAACAAAATCGAGTCCTCGTGTGTGCAC CTTCCAATGCGGCGGTTGATGAACTTATGAAAAAAATTATCCTCGAATTTAAAGAAAAATGTAAAGACAA GAAGAATCCTTTGGGAAACTGTGGAGATATAAATTTAGTACGACTAGGTCCAGAAAAGTCTATTAATACA GAGGTCTTAAAATTCAGTTTGGACAGCCAAGTCAACCATAGAATGAAAAAAGACTTGCCTTCTCATATTC AAGAAATGCTTAGAAGAAAAGAAATTCTAGATGCTCAACTTGATGAGCTTTCTCGTCAGCGAGCTCTGTG CCGAGGTGGGCGGGAGATGCAGAGGCAAGAATTAGATGAACACATTGCCATAGTCTCAAAAGAAAGGCAA GAACTTGCTTCGAAAATTAAAGAGGTTCAGGGACGCCCACAGAGAGCACAGAATACCATCATCTTGGAGT CCCATGTCATCTGCTGCACATTGAGCACTAGTGGTGGTTTATTGCTTGAGTCTGCTTTTCGAGGGCAAGG GGGTGTCCCCTTCAGTTGTGTCATCGTAGATGAGGCTGGGCAGTCTTGTGAAGTTGAGACACTTTCTCCA CTCATCCACCGCTGCAATAAACTTATCCTAGTAGGAGACCCCAAACAGCTCCCTCCCACAGTCATCTCTA TGAAAGCACAGGAGTATGGCTATGACCAGTCGATGATGGCCCGATTCTGCAAGCTGCTGGAAGAGAATGT GGAGCAGAACATGATTGGCAGGCTGCCGGTGTTACAGCTTACCATTCAGTACAGGATGCATCCAGACATA TGTCTTTTCCCTTCTAATTACGTTTATAACAAAAACCTGAAGACAAATAGATTGACTGAATCCATTCGAT GTTCATCAGAGTGGCCATTTCAGCCCTACCTCGTGTTTGATGTTGGAGATGGTTCAGAACGACGGGATAA TGACTCATATATAAATGTTCAAGAAATAAAGTTGGTGATGGAAATAATTAAACTTATTAAAGAGAAAAGA AAAGATATTTCCTTCCGAAATATTGGCATAATAACCCATTACAAGGCTCAGAAGACGATGATCCAGAAGG ATTTGGAGAAAGAATTTGATAAGAAAGGACCTGCAGAAGTGGACACAGTAGATGCCTTCCAGGGCCGGCA GAAAGACTGTATCATCGTTACCTGTGTCAGGGCAAGTGCTGTGCAAGGCTCAATAGGATTCCTGGCAAGT TTGCAGAGATTGAATGTCACCATTACACGAGCCAAGTATAGCCTCTTTATCCTTGGACATTTGAGGACTC TGATGGAAAACCAGCATTGGTATGAACTGATTCAGGATGCTCAGAAGCGTGGGGCCATTATTAAGACCAG TGACCCAAACTATAGACATGACGCAATGAAGATTCTGAAACTGAAGCCTGTGCTACAGAGGAGTCTGACC CATCCCCCAGCCACTGCCCCGGAGGCACCCAGACCCCAGGGTGGCTTGCCCAGCAACAGACTGGACAGTG GACTTGCCACAACATCTTTTGCTGCTTCTTTGTATCACACACCCTCTGATACTGTCACTTCAAAGGGACC TGAAAGGCCACTTCTTCAAGACCGACTTCGAGATCCACGACTACTCAGGAGATTGGATGCTGAAGCCAAG GGAACATTCCTGAAGGATCCACAGCCCGTTAGCCCCCAGCTCCCCGGGGTAGTTCATCTCTTGGGAGAGC CTGGCTTCCCTGTGGTTTTCCAGGACCTAGGTTTTGTTGTGCCGCCATCCACTGCCATTGTTGCTCCTCT GGGCAGCCACAGGTCACCTATGCAGGCTGAGCCACCACCTGCTCACCCTGCTGCTGCCGCCTCCACAAGT AAGAGGAAGTACAGTGACCCAGATGCTGGGCTCAGCCACAAAAGAGAACCCAGGGCCTTCAGTGGAGAGC AGGGGAGGCATGGCTCTGTGACTCATCACGTGCTGAGAAGCACTGACTGGGACAGGAGGAGGCTGGATGA CAGCAGTGCCAAGAGGAGACAATTTCTA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA Protein Sequence (showhide) >MR217962 representing NM_198033 Red=Cloning site Green=Tags(s) MSTCCWCTPGGSSTIDVLKRYASSTGSSEFQTADEDLCYCLECVAEYHRARDEVPFLHEVLWELETLRLV SHFEKSMKAEAEDDDDLYIVDNNGEEQLFDCSGQDFENKLRVPLFEILKYPYLLLHERVNELCVEALCRM EQNNCSFQVFDKYPGIYLFLVHPNEMVRRWAILTARNLGKVDRDDYYDLQEVLTCLFKVIELGLLESPDI YTSSVLEKGKLILLPAHMYDTTNYKNYWLGICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEKQSDD DSMDPFWPALHCFMVILDRLGSKVWGQLIDPIEAFQTIINNESYNREIQNIRNSSIRTKLEPEPHFDDMV TCSQIVYNFNPEKTKKDSGWRSAICPDYCPNMYEEMETLANVLQSDIGQDMRVHNSTFLWFIPFVQSLMD LKDLGVAYIVEVIHHLYSEVKDVLNQTDAVCDKVTEFFILILISVIELHRNKKCLHLLWVSSQQWVEAVV KCAKLPTTAFVRSCEKSPGSTSRGAAIMSSLALHSVQSNSVQLACVQLIRGLLKEGYQLGQQTLCKRFWD KLNLFLRGNLSLGWQLTGQETHELQMCLKQIIRNIKFKMPQYSTFGDSTSTFKTPPSFKEESDKIDRKHK KNIYCLENCSPVSSKEPMKADTHRVLMKVNTTEEENFKQHYIDLNEEEQEPLPAELCLKQKSEALFSESA QEQVKISAEKSGKESSSYAPSNSTSRNGPEWGCDRGVIMSAHSLTDSSSDFMEQVSTSNEDVSLKDGSVG KTSKPSFKLQKDEICAKLSHVIKKQIRKSTLVDNIIDLEENTAISDLENCSGTDGGALKEDSIGHNVPSD PVLDDKHEEQKSQNSSLFKKEIKSEELDNSSSDDEDKLQIQEGRADDDLVSFTEVTDTLVKAPCEGHVKM VVESRDKEMRESTALTSNLVEGQVPHDSSKPLVAGRQIDLCNITLISQTTVIQFPSGLSKQNSFQLQKGD KRCLTANQNSAATCRGQVIVISDSDEEEDEDEDERSSSEENIKQSKACIGKDCSEHRSLAVNASVEKQLV KEEERYPVEFEDSESQVFEFESSSEVFSVWQDHKIDSKNSLQGEQKSYVTHVADSTNNNLGCGDSVSEEV VRNKAEGVKEHAGPHSSVSAEEFCKTGVKKPKRKRYDKVTAEDPQRPSSSVGTDQLPDRRDLTESDLKSA DMGMATPSSSVERDSTILQKSTKSRTHSKPVRKVPASKATKKTHSDTRRGQSKSSCYISCRTSPAIVPPK KLRQCPEPTSTVEKLGLKKAPRKAFELSQRSLECIVQLRDHGKTVGVVDAPKKAKLISPQTLSIKNNKKL LTSQDLQFQRLMRSRSHKKRDFDYKNTDTVRVSRIVQGSDVLEADSDEPDDHRVSEPLAISNEKQLAKCM LSKTEVAEASSDPWVTGITCLVNQCESRVLSGGVPTDVVMVSASEDPVDGGAVTVQVGEVASVKAAEPAS SSDTDDDDNLFLTQHDPQDMDLCSQLENKTIIVAHKKDTVQREDSLSRPQLESLSITKCKYKDCVETTKN QGEYCPRHSEAKAADDGLFRKPGLPLSVARPLRPTTTKIFSSSSASRTANLSKSLESTTLQQSALKNKSS GAQPNLKVTPPSSMGSQKPVAEVKSLCNIFHFQTPSSSSKQSCKLTFSENRPTSAASPVNILLPSQSIFD TFIKEVLKWKYQMFLNFDKCGAPTSLCQSISRPVPVRFQDCAEYFNVFLPLIILNAFETVAQEWLSSPNK ENFYQLQLRKFPADYKKYWEFLIYLNESELAKQLHPKENDLVFLAPEKSYMDRHGMQDCSHYYCGYVHKF RRTSVMRSGKAECSLCIQTQDTLPASVKNLTRCIVISSLVTTQRKLKAMSLLSSRNQLARAVLNPNPMDF CTKDLLTTTSERIVAYLKDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTEN QRKGHSDENFNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGPEKSINT EVLKFSLDSQVNHRMKKDLPSHIQEMLRRKEILDAQLDELSRQRALCRGGREMQRQELDEHIAIVSKERQ ELASKIKEVQGRPQRAQNTIILESHVICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEVETLSP LIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFCKLLEENVEQNMIGRLPVLQLTIQYRMHPDI CLFPSNYVYNKNLKTNRLTESIRCSSEWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKEKR KDISFRNIGIITHYKAQKTMIQKDLEKEFDKKGPAEVDTVDAFQGRQKDCIIVTCVRASAVQGSIGFLAS LQRLNVTITRAKYSLFILGHLRTLMENQHWYELIQDAQKRGAIIKTSDPNYRHDAMKILKLKPVLQRSLT HPPATAPEAPRPQGGLPSNRLDSGLATTSFAASLYHTPSDTVTSKGPERPLLQDRLRDPRLLRRLDAEAK GTFLKDPQPVSPQLPGVVHLLGEPGFPVVFQDLGFVVPPSTAIVAPLGSHRSPMQAEPPPAHPAAAASTS KRKYSDPDAGLSHKREPRAFSGEQGRHGSVTHHVLRSTDWDRRRLDDSSAKRRQFL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Restriction Sites	SgfI-MluI      Cloning Scheme for this gene      Plasmid Map
ACCN	NM_198033
ORF Size	7938 bp
OTI Disclaimer	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation	This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_198033.2, NP_932150.2
RefSeq Size	10970 bp
RefSeq ORF	7941 bp
Locus ID	269254
UniProt ID	A2AKX3
MW	298 kDa
Gene Summary	Probable RNA/DNA helicase involved in diverse aspects of RNA metabolism and genomic integrity. Plays a role in transcription regulation by its ability to modulate RNA Polymerase II (Pol II) binding to chromatin and through its interaction with proteins involved in transcription. Contributes to the mRNA splicing efficiency and splice site selection. Required for the resolution of R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site, allowing XRN2 recruitment and XRN2-mediated degradation of the downstream cleaved RNA and hence efficient RNA polymerase II (RNAp II) transcription termination (By similarity). Required for the 3' transcriptional termination of PER1 and CRY2, thus playing an important role in the circadian rhythm regulation (PubMed:22767893). Involved in DNA double-strand breaks damage response generated by oxidative stress. In association with RRP45, targets the RNA exosome complex to sites of transcription-induced DNA damage (By similarity). Plays a role in the development and maturation of germ cells: essential for male meiosis, acting at the interface of transcription and meiotic recombination, and in the process of gene silencing during meiotic sex chromosome inactivation (MSCI) (PubMed:23593030). Plays a role in neurite outgrowth in hippocampal cells through FGF8-activated signaling pathways. Inhibits retinoic acid-induced apoptosis. May be involved in telomeric stability through the regulation of telomere repeat-containing RNA (TERRA) transcription (By similarity).[UniProtKB/Swiss-Prot Function]

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