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Cdk12 (NM_001109626) Mouse Tagged ORF Clone
CAT＃: MR218603
- TrueORF®
Cdk12 (Myc-DDK-tagged) - Mouse cyclin-dependent kinase 12 (Cdk12), transcript variant 1
ORF Plasmid: tGFP
"NM_001109626" in other vectors (4)
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CNY 10,160.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | 1810022J16Rik; AI646528; Crk7; Crkrs; D11Ertd752e; Pksc |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR218603 representing NM_001109626
Red=Cloning site Blue=ORF Green=Tags(s) CTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCCGGCGC GCCC ATGCCCAATTCCGAGAGACATGGGGGCAAGAAGGACGGGAGCGGAGGAGCTTCTGGAACTTCGCAGCCGT CATCGGGAGGTGGCAGCTCCAACAGCAGGGAGCGTCACCGCTTGGTGTCGAAGCACAAGCGGCATAAGTC CAAGCACTCCAAAGACGTGGGGCTGGTGACCCCCGAAGCGGCATCTTTGGGTACCATAATCAAACCACTG GTGGAGTACGATGACATCAGCTCTGATTCAGACACCTTCTCCGATGACACGGCCTTCAAATCAGACCGGA GGGAGAACGAGGAACGTCGGGGAACGGATCGGAGCGATCGCCTGCACCGACATCGTCACCACCAGCACCG GCGGTCCCGAGACTTGCTAAAAACTAAACAGACGGAAAAGGAAAAAAATCAGGAAGTCTCCAAATCTGGA TCTATGAAGGACCGGGTATCGGGCAGTTCCAAACGG[AT]CCGTGGAGGGGAGTGATGATTATGGGAAGG CCCAGCTATCCAAAAGCGGCAGCAAGGAATCCAGGTCGTCCAAAATGCACAAGGAGAAGACCCGCAAAGA GCGAGAGTTAAAGTCTGGATACAAGGACCGGAGTAAAAGTCATCGGAAAAGGGAAACACCCAAAAGTTAC AAAACCGTGGCTAGCCCTAAACGGAGATCCAGGAGTCCCCATAGGAAATGGTCTGACAGTTCCAAGCAAG ATGACAGCCCTTCCGGAGCTTCTTATGGCCAAGACTACGATCTTAGCCCCCCAAGGTCTCACACTTCTAG CAACTATGACTCCTACAAGAAGAGTCCTGGAAGTACCTCAAGAAGGCAGTCAATCAGCCCACCTTACAAA GAGCCTTCTGCTTACCAGTCCAGCACTCGGTCACCCAGTCCTTACAGCCGACGACAGAGGTCTGTGAGTC CCTATAGCCGGAGACGGTCCTCCAGCTATGAAAGGAGCGGCTCTTACAGCGGGAGATCACCCAGCCCCTA TGGCCGAAGGCGATCAAGCAGCCCTTTCCTGAGCAAGAGGTCTCTGAGTCGGAGTCCACTCCCCAGTAGG AAATCCATGAAGTCCAGAAGTAGAAGTCCTGCATATTCAAGACACTCATCTTCTCATAGTAAAAAGAAGC GATCCGGGTCACGCAGTCGTCATTCCAGTATCTCACCTGTCAGGCTTCCATTGAATTCCAGCCTGGGAGC TGAACTCAGTAGAAAAAAGAAGGAAAGAGCAGCAGCTGCTGCAGCAGCAAAAATGGATGGAAAAGAGTCC AAGAGTTCACCTATAATTTTGCCTAAAAAAGAGAAACTTGAGGTGAAGGAGTCAGGGTTAGAGTCTAAAA AGTTACCCAGAAGTATAAAATCAGAAAAATCGACCCCAGATACTGAACTGGTTACTGTAGCACATTCAAA CCCAGAGGTAAAACATTGTTTAGACACAGGGAAGGTTAGGTTGGATGAGAACTTGCAGAAGCATCCTGCT AAGGATTTGAAAGCACAGGGAACAAAGGACGTTAAACCTGTAGCACCGAAAGAGGTGATTGTTACTTCAA AGGAGACAGAGACATCAGAAAAGGAGACCCTTCCACCTCTTCCCACAATTACTTCTCCACCCCCTTTACC AGCTACTACCCCTCCACCTCAGACACCCCCTTTGCCACCTTTGCCTCCACTACCAGCTATTCCGCTGCAG CCACCTCTGCCTCCTCCCCAACCACCATTTAGTCAAGTTCCTGTTTCAAGTACTTCAATTTTACCCTCTT CTCCTCACCCAAGGACATCTACTCTATCCTCTCAGACAAATTCTCAGCCCCCTGTACAGGTTTCTATGAA GACTCAAGTATCTATAACAGCTGCTATTCCACATCTGAAGACTTCAACATTGCCTCCTCTGCCCCTCCCT CCCCTATTACCTGGAGATGATGACATGGATAGTCCAAAAGAAACACTTCCTTCAAAGCCTGCAAAGAAAG AGAAGGAACAGAGGACTCGCCACTTGCTTACAGACTTGCCTCTTCCTCCTGAGCTACCAGGAGGAGATCC ATCGCCTCCAGATTCTCCAGAGCCAAAGGCAATTACACCACCTCAACAACCATATAAAAAGAGACCAAAA ATTTGTTGTCCACGTTATGGAGAAAGAAGACAAACAGAAAGTGATTGGGGGAAGCGCTGTGTGGACAAGT TTGACATTATTGGGATTATTGGAGAGGGGACCTATGGCCAAGTATATAAAGCCAAGGACAAAGACACAGG AGAACTAGTAGCTCTGAAGAAGGTTCGGCTGGACAATGAGAAAGAGGGCTTCCCAATCACAGCCATCCGG GAGATCAAGATTCTTCGTCAATTAGTTCACCAGAGTGTTGTAAACATGAAGGAAATTGTCACAGACAAAC AAGATGCACTGGATTTCAAGAAGGACAAAGGTGCCTTTTACCTTGTATTTGAATATATGGACCATGACTT AATGGGACTGCTTGAATCAGGTTTGGTGCACTTTTCTGAGGACCATATCAAGTCATTTATGAAACAGCTA ATGGAAGGACTGGATTACTGTCACAAAAAGAATTTCCTCCATCGGGATATTAAATGTTCTAACATTTTGC TGAATAACAGCGGGCAAATCAAACTGGCAGATTTTGGACTTGCTCGGCTCTATAACTCTGAAGAGAGTCG CCCTTACACAAACAAAGTCATCACTCTTTGGTATCGACCTCCAGAGCTTCTTCTTGGAGAGGAAAGATAC ACACCAGCCATTGATGTTTGGAGCTGTGGGTGCATCCTTGGAGAACTGTTCACAAAGAAACCTATTTTTC AAGCCAATTTAGAACTGGCTCAGCTAGAACTTATCAGTCGTCTCTGTGGTAGTCCTTGTCCAGCAGTGTG GCCTGATGTTATCAAGCTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATACAGGAGACGCCTAAGA GAAGAATTCTCTTTCATTCCTTCAGCGGCACTTGATCTATTGGACCACATGCTGACACTGGATCCTAGCA AGAGGTGCACAGCTGAACAGACCCTACAGAGTGACTTTCTTAAAGATGTGGAACTCAGCAAAATGGCACC TCCAGACCTACCTCACTGGCAGGATTGCCATGAATTGTGGAGTAAGAAACGTCGACGGCAGCGACAGAGT GGTATTGTGATAGAAGATCCACCTCCGTCCAAAGCTTCTAGAAAAGAAACTACCTCAGGGACAACAGCTG AGCCTGTGAAAAACAATAGCCCAGCACCACCTCAGCCTGCTCCTGTCAAGGCAGAGCCTGGTCCAGGGGA TGCAGTAGGCCTTGGTGACATCACACAGCAGTTGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTT CAGAGCCAAACTGACCTGAGCATCCCTCAGATGGCACAGCTGCTTAATATCCACTCCAATCCAGAGATGC AACAGCAGCTTGAAGCCTTGAATCAGTCTATTAGTGCACTGACTGAAGCCAGTTCCCAGCAGCAGGACTC AGAATCCATAGCCCCTGAAGAATCATTGAAGGAGGTACCTTCTGTACCTGTGGTCCTGCCTCCTGCTGAA CAGACAACTCCTGAAGCTTCAAACACACCAGCTGACATGCAGAATGTGTTGGCAGTTCTCTTGAGTCAGC TGATGAAAACCCAAGAGCCAGCAGGTAACCTGGAGGAAAACACCAATGACAAGAATAGTGGGCCACAGGG GCCCCGAAGAACTCCTACAATGCCACAGGAGGAGGCAGCAGCATGTCCTCCTCACATTCTTCCACCAGAG AAGAGGCCCCCTGAGCCCCCTGGACCTCCACCGCCGCCACCTCCACCCCCTCTGGTTGAAGGCGATCTTT CCAGCGCCCCCCAGGAGTTGAATCCCGCCGTGACAGCCGCCTTGCTGCAACTTTTATCCCAGCCTGAAGC AGAGCCTCCTGGCCACCTGCCACATGAGCACCAGGCCTTGAGACCAATGGAATACTCCACCCGATCCCAT CCAAACAGGACTTACGGAAATACTGATGGGCCTGAGACAGGGTTCAGTTCCGCTGACACTGATGAACGCA GTTCTGGTCCAGCCTTGACAGAATCTTTGGTTCAGACCCCGGTGAAGAACAGGACCTTCTCAGGCTCTGT GAGCCACCTTGGGGAGTCCAACAGCTACCAGGGCACAGGGTCAGTGCAGTTCCCAGGGGACCAGGACCTC CGTTTTACCAGGGTTCCCTTAGCATTACACTCAGTGGTTGGGCAACCATTCCTCAAGTCTGAGGGAAATA GCAACTCTGTGGTACATGCAGAGACCAAATTGCAAAACTATGGGGAGCTGGGACCGGGAACCACTGGGGC CAACAGCTCAGGAACAACGCTTCAGTGGGGGGGCCCAGCTCAGTCTTATGGAAAACCCTACAGGGGGGCT GCAAGAGTCCTACCACGAGGGGGAAGAGGGAGAGGAGTTCCTTAT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR218603 representing NM_001109626
Red=Cloning site Green=Tags(s) MPNSERHGGKKDGSGGASGTSQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDVGLVTPEAASLGTIIKPL VEYDDISSDSDTFSDDTAFKSDRRENEERRGTDRSDRLHRHRHHQHRRSRDLLKTKQTEKEKNQEVSKSG SMKDRVSGSSKRXXVEGSDDYGKAQLSKSGSKESRSSKMHKEKTRKERELKSGYKDRSKSHRKRETPKSY KTVASPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPPRSHTSSNYDSYKKSPGSTSRRQSISPPYK EPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSR KSMKSRSRSPAYSRHSSSHSKKKRSGSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES KSSPIILPKKEKLEVKESGLESKKLPRSIKSEKSTPDTELVTVAHSNPEVKHCLDTGKVRLDENLQKHPA KDLKAQGTKDVKPVAPKEVIVTSKETETSEKETLPPLPTITSPPPLPATTPPPQTPPLPPLPPLPAIPLQ PPLPPPQPPFSQVPVSSTSILPSSPHPRTSTLSSQTNSQPPVQVSMKTQVSITAAIPHLKTSTLPPLPLP PLLPGDDDMDSPKETLPSKPAKKEKEQRTRHLLTDLPLPPELPGGDPSPPDSPEPKAITPPQQPYKKRPK ICCPRYGERRQTESDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIR EIKILRQLVHQSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQL MEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERY TPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLR EEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQS GIVIEDPPPSKASRKETTSGTTAEPVKNNSPAPPQPAPVKAEPGPGDAVGLGDITQQLNQSELAVLLNLL QSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEASSQQQDSESIAPEESLKEVPSVPVVLPPAE QTTPEASNTPADMQNVLAVLLSQLMKTQEPAGNLEENTNDKNSGPQGPRRTPTMPQEEAAACPPHILPPE KRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRSH PNRTYGNTDGPETGFSSADTDERSSGPALTESLVQTPVKNRTFSGSVSHLGESNSYQGTGSVQFPGDQDL RFTRVPLALHSVVGQPFLKSEGNSNSVVHAETKLQNYGELGPGTTGANSSGTTLQWGGPAQSYGKPYRGA ARVLPRGGRGRGVPY TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
AscI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001109626 |
| ORF Size | 4455 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001109626.1, NP_001103096.1 |
| RefSeq Size | 7669 bp |
| RefSeq ORF | 4455 bp |
| Locus ID | 69131 |
| UniProt ID | Q14AX6 |
| MW | 164.1 kDa |
| Gene Summary | Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates 'Ser-5' in CTD repeats that are already phosphorylated at 'Ser-7', but can also phosphorylate 'Ser-2'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC224546 | Cdk12 (untagged) - Mouse cyclin-dependent kinase 12 (Cdk12), transcript variant 1, (10ug) |
CNY 19,000.00 |
|
| MG218603 | Cdk12 (tGFP-tagged) - Mouse cyclin-dependent kinase 12 (Cdk12) transcript variant 1, (10ug) |
CNY 14,350.00 |
|
| MR218603L3 | Lenti ORF clone of Cdk12 (Myc-DDK-tagged) - Mouse cyclin-dependent kinase 12 (Cdk12), transcript variant 1 |
CNY 14,920.00 |
|
| MR218603L4 | Lenti ORF clone of Cdk12 (mGFP-tagged) - Mouse cyclin-dependent kinase 12 (Cdk12), transcript variant 1 |
CNY 14,920.00 |
